Skip to main content
Journal of Medical Genetics logoLink to Journal of Medical Genetics
. 1973 Dec;10(4):392–395. doi: 10.1136/jmg.10.4.392

The Genetic Variability of Thalassaemia. A Family Study

E De La Torre 1, E Svarch 1, B Colombo 1
PMCID: PMC1013064  PMID: 4774832

Abstract

Two step-brothers, homozygotes for β-thalassaemia, have been studied. One of them showed the characteristics of Cooley's anaemia, whereas the other was almost symptomless. The existence of two different β-thalassaemic genes is discussed in relation to the haematological and clinical findings.

Full text

PDF
392

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BETKE K., MARTI H. R., SCHLICHT I. Estimation of small percentages of foetal haemoglobin. Nature. 1959 Dec 12;184(Suppl 24):1877–1878. doi: 10.1038/1841877a0. [DOI] [PubMed] [Google Scholar]
  2. Bernini L. F. Rapid estimation of hemoglobin A2 by DEAE chromatography. Biochem Genet. 1969 Jan;2(4):305–310. doi: 10.1007/BF01458491. [DOI] [PubMed] [Google Scholar]
  3. Nienhuis A. W., Laycock D. G., Anderson W. F. Translation of rabbit haemoglobin messenger RNA by thalassaemic and non-thalassaemic ribosomes. Nat New Biol. 1971 Jun 16;231(24):205–208. doi: 10.1038/newbio231205a0. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Medical Genetics are provided here courtesy of BMJ Publishing Group

RESOURCES