Skip to main content
Journal of Medical Genetics logoLink to Journal of Medical Genetics
. 1976 Jun;13(3):208–211. doi: 10.1136/jmg.13.3.208

Pre-eclampsia/eclampsia in twin pregnancies.

A McFarlane, J S Scott
PMCID: PMC1013394  PMID: 933121

Abstract

A study of 1045 twin gestations with regard to known or likely zygosity and the incidence of pre-eclampsia/eclampsia failed to reveal differences between known dizygous twins and like-sex 'presumed' and 'estimated' monozygous twins except in the 'estimated' data for multigravidae. There was a threefold increase in the incidence for twins as opposed to singleton pregnancies. These results are discussed in relation to increased conceptus-mother antigenic differences. It is suggested that the risk of gestosis in twin pregnancy involves more than a summation of that operating in two singleton pregnancies.

Full text

PDF

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ADAMS E. M., MACGILLIVRAY I. Long-term effect of preeclampsia on blood-pressure. Lancet. 1961 Dec 23;2(7217):1373–1375. doi: 10.1016/s0140-6736(61)91196-5. [DOI] [PubMed] [Google Scholar]
  2. Cameron A. H. The Birmingham twin survey. Proc R Soc Med. 1968 Mar;61(3):229–234. [PMC free article] [PubMed] [Google Scholar]
  3. Enders T., Stern C. The Frequencies of Twins, Relative to Age of Mothers, in American Populations. Genetics. 1948 May;33(3):263–272. doi: 10.1093/genetics/33.3.263. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. James W. H. Excess of like sexed pairs of dizygotic twins. Nature. 1971 Jul 23;232(5308):277–278. doi: 10.1038/232277a0. [DOI] [PubMed] [Google Scholar]
  5. NAEYE R. L. THE FETAL AND NEONATAL DEVELOPMENT OF TWINS. Pediatrics. 1964 Apr;33:546–553. [PubMed] [Google Scholar]
  6. Nylander P. P. The determination of zygosity--a study of 608 pairs of twins born in Aberdeen. J Obstet Gynaecol Br Commonw. 1970 Jun;77(6):506–510. doi: 10.1111/j.1471-0528.1970.tb03557.x. [DOI] [PubMed] [Google Scholar]
  7. PLATT R., STEWART A. E., EMERY E. W. The aetiology, incidence, and heredity of pre-eclamptic toxaemia of pregnancy. Lancet. 1958 Mar 15;1(7020):552–556. doi: 10.1016/s0140-6736(58)91192-9. [DOI] [PubMed] [Google Scholar]
  8. SALZMANN K. D. Do transplacental hormones cause eclampsia? Lancet. 1955 Nov 5;269(6897):953–956. doi: 10.1016/s0140-6736(55)92793-8. [DOI] [PubMed] [Google Scholar]
  9. Selvin S. The number of pregnancies prior to the birth of twins. Ann Hum Genet. 1971 May;34(4):427–429. doi: 10.1111/j.1469-1809.1971.tb00255.x. [DOI] [PubMed] [Google Scholar]
  10. Stevenson A. C., Davison B. C., Say B., Ustuoplu S., Liya D., Abul-Einen M., Toppozada H. K. Contribution of fetal/maternal incompatibility to aetiology of pre-eclamptic toxaemia. Lancet. 1971 Dec 11;2(7737):1286–1289. doi: 10.1016/s0140-6736(71)90604-0. [DOI] [PubMed] [Google Scholar]
  11. Toivanen P., Hirvonen T. Sex ratio of newborns: preponderance of males in toxemia of pregnancy. Science. 1970 Oct 9;170(3954):187–188. doi: 10.1126/science.170.3954.187. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Medical Genetics are provided here courtesy of BMJ Publishing Group

RESOURCES