Skip to main content
Journal of Medical Genetics logoLink to Journal of Medical Genetics
. 1977 Feb;14(1):16–19. doi: 10.1136/jmg.14.1.16

Immunoglobulin levels in dystrophia myotonica.

D F Roberts, W G Bradley
PMCID: PMC1013499  PMID: 839494

Abstract

Levels of immunoglobulins IgG, IgA, and IgM were measured in 38 patients with myotonic dystrophy, in normal members of their families, and in matched controls. Log IgG was significantly reduced in the patients. IgG investigation provides a further parameter to appraise the status of apparently unaffected members of myotonic dystrophy families.

Full text

PDF
16

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bundey S., Carter C. O., Soothill J. F. Early recognition of heterozygotes for the gene for dystrophia myotonica. J Neurol Neurosurg Psychiatry. 1970 Jun;33(3):279–293. doi: 10.1136/jnnp.33.3.279. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Grove D. I., O'Callaghan S. J., Burston T. O., Forbes I. J. Immunological function in dystrophia myotonica. Br Med J. 1973 Jul 14;3(5871):81–83. doi: 10.1136/bmj.3.5871.81. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Mancini G., Carbonara A. O., Heremans J. F. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry. 1965 Sep;2(3):235–254. doi: 10.1016/0019-2791(65)90004-2. [DOI] [PubMed] [Google Scholar]
  4. Polgar J. G., Bradley W. G., Upton A. R., Anderson J., Howat J. M., Petito F., Roberts D. F., Scopa J. The early detection of dystrophia myotonica. Brain. 1972;95(4):761–766. doi: 10.1093/brain/95.4.761. [DOI] [PubMed] [Google Scholar]
  5. Wochner R. D., Drews G., Strober W., Waldmann T. A. Accelerated breakdown of immunoglobulin G (IgG) in myotonic dystrophy: a hereditary error of immunoglobulin catabolism. J Clin Invest. 1966 Mar;45(3):321–329. doi: 10.1172/JCI105346. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. ZINNEMAN H. H., ROTSTEIN J. A study of gamma globulins in dystrophia myotonica. J Lab Clin Med. 1956 Jun;47(6):907–916. [PubMed] [Google Scholar]

Articles from Journal of Medical Genetics are provided here courtesy of BMJ Publishing Group

RESOURCES