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Journal of Medical Genetics logoLink to Journal of Medical Genetics
. 1977 Apr;14(2):134–136. doi: 10.1136/jmg.14.2.134

Reproductive ability of an adult female with Silver-Russell syndrome.

H K Abramowicz, H M Nitowsky
PMCID: PMC1013531  PMID: 856957

Abstract

An adult female with typical features of Silver-Russell dwarfism gave birth to a viable infant. Despite the abnormalities in sexual development that may be associated with the Silver-Russell syndrome, fertility is not necessarily impaired, at least in females. The growth and development of children with the Silver-Russell syndrome have been studied (Silver, 1964; Tanner et al., 1975). There is, however, virtually no information available about adult patients with this syndrome. It is known that both male and female Silver-Russell dwarfs develop secondary sexual characteristics (Rimoin, 1969; McDowell and Sproles, 1973) but fertility of these patients has not been described previously.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brehme H., Schröter R. Hautleistenbefunde von 15 Patienten mit Russell-Silver-Syndrom. Humangenetik. 1967 Nov 29;5(1):28–35. doi: 10.1007/BF00286208. [DOI] [PubMed] [Google Scholar]
  2. Fuleihan D. S., Der Kaloustian V. M., Najjar S. S. The Russell-Silver syndrome: report of three siblings. J Pediatr. 1971 Apr;78(4):654–657. doi: 10.1016/s0022-3476(71)80469-9. [DOI] [PubMed] [Google Scholar]
  3. McDowell R. V., Sproles E. T., 3rd The Russell-Silver syndrome: a nine-year follow-up. Am J Dis Child. 1973 Dec;126(6):794–796. doi: 10.1001/archpedi.1973.02110190640011. [DOI] [PubMed] [Google Scholar]
  4. REISTER H. C., SCHERZ R. G. SILVER SYNDROME. A REPORT OF TWO CASES AND A REVIEW OF THE LITERATURE. Am J Dis Child. 1964 Apr;107:410–416. [PubMed] [Google Scholar]
  5. SILVER H. K. ASYMMETRY, SHORT STATURE, AND VARIATIONS IN SEXUAL DEVELOPMENT. A SYNDROME OF CONGENITAL MALFORMATIONS. Am J Dis Child. 1964 May;107:495–515. doi: 10.1001/archpedi.1964.02080060497011. [DOI] [PubMed] [Google Scholar]
  6. Tanner J. M., Lejarraga H., Cameron N. The natural history of the Silver-Russell syndrome: a longitudinal study of thirty-nine cases. Pediatr Res. 1975 Aug;9(8):611–623. doi: 10.1203/00006450-197508000-00001. [DOI] [PubMed] [Google Scholar]

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