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. 2023 Apr 16;15(4):976. doi: 10.3390/v15040976

Table 5.

Logistic Regression Analysis for the efficacy of treatment with nirmatrelvir/ritonavir (prevention of hospitalization/intubation/death) based on treatment adherence (n = 200 Group A, partial compliance n = 5).

Variable OR (95% CI) p Value
COVID-19 vaccination

  • Complete scheme (2 booster doses)

 0.14 (0.09–0.18) <0.001

  • Incomplete scheme

 1.03 (0.97–1.23) <0.001

  • Unvaccinated

 1.25 (1.16–1.62) <0.001
Age (HR for each 10-year increase) 1.78 (1.63–1.94) <0.001
Male sex 1.04 (1.04–1.15) <0.001
Previous SARS-CoV-2 infection

  • Yes

 0.54 (0.47–0.71) <0.001

  • No

 1.02 (0.97–1.12) <0.001
Treatment adherence

  • Complete

 0.27 (0.15–0.47) <0.001

  • Partial

 1.12 (1.08- 1.56) <0.001