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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1991 Aug;54(8):683–688. doi: 10.1136/jnnp.54.8.683

Magnetic resonance imaging in monitoring the treatment of multiple sclerosis: concerted action guidelines.

D H Miller 1, F Barkhof 1, I Berry 1, L Kappos 1, G Scotti 1, A J Thompson 1
PMCID: PMC1014470  PMID: 1940938

Abstract

Serial gadolinium enhanced MRI of the brain detects much clinically silent disease activity in early relapsing-remitting and secondary progressive multiple sclerosis (MS), and thus has an important role in monitoring the effects of therapy. Based on the proceedings of a recent Commission of the European Communities (CEC) workshop and a review of the literature, guidelines are presented for using MRI to monitor treatment trials in MS. The guidelines consider: A) MRI system and techniques; B) patient selection; C) trial design; D) analysis of results. Priorities for future research are also indicated.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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