Table 2.
Urinary levels of tryptophan (TRP) and its metabolites: 5-hydroxyindoleacetic acid (5-HIAA), kynurenine (KYN), kynurenic acid (KYNA), and quinolinic acid (QA) in the control group and patients with diarrhea-predominant irritable bowel syndrome (IBS-D); all results expressed in units—mg/gCr; average ± SD.
| TRP and Its Metabolites | Group I (Control) |
Group II (IBS-D) |
p-Value |
|---|---|---|---|
| TRP | 11.4 ± 2.31 | 12.5 ± 2.21 | >0.05 |
| 5-HIAA | 4.92 ± 0.78 | 6.81 ± 0.91 | <0.001 |
| KYN | 0.67 ± 0.22 | 0.83 ± 0.21 | >0.01 |
| KYNA | 2.41 ± 0.66 | 2.17 ± 0.52 | >0.05 |
| QA | 6.18 ± 1.02 | 7.25 ± 0.87 | <0.01 |