Abstract
Three patients with polymyositis refractory to conventional steroid and immunosuppressive treatment, but responsive to cyclosporin A, are described. In a fourth patient cyclosporin A was used as a first line drug in combination with steroids in the treatment of life-threatening dermatomyositis. Cyclosporin A in the management of polymyositis/dermatomyositis requires formal assessment of its costs and benefits compared with conventional treatments.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Ansell B. M. Management of polymyositis and dermatomyositis. Clin Rheum Dis. 1984 Apr;10(1):205–213. [PubMed] [Google Scholar]
- Bendtzen K., Tvede N., Andersen V., Bendixen G. Cyclosporin for polymyositis. Lancet. 1984 Apr 7;1(8380):792–793. doi: 10.1016/s0140-6736(84)91301-1. [DOI] [PubMed] [Google Scholar]
- Carpenter S., Karpati G., Heller I., Eisen A. Inclusion body myositis: a distinct variety of idiopathic inflammatory myopathy. Neurology. 1978 Jan;28(1):8–17. doi: 10.1212/wnl.28.1.8. [DOI] [PubMed] [Google Scholar]
- Dawkins R. L., Mastaglia F. L. Cell-mediated cytotoxicity to muscle in polymyositis. Effect of immunosuppression. N Engl J Med. 1973 Mar 1;288(9):434–438. doi: 10.1056/NEJM197303012880903. [DOI] [PubMed] [Google Scholar]
- Ejstrup L. Severe dermatomyositis treated with cyclosporin A. Ann Rheum Dis. 1986 Jul;45(7):612–613. doi: 10.1136/ard.45.7.612-b. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Zabel P., Leimenstoll G., Gross W. L. Cyclosporin for acute dermatomyositis. Lancet. 1984 Feb 11;1(8372):343–343. doi: 10.1016/s0140-6736(84)90391-x. [DOI] [PubMed] [Google Scholar]