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. 1993 Apr;56(4):419–422. doi: 10.1136/jnnp.56.4.419

Coding of movement direction and amplitude in Parkinson's disease: are they differentially impaired (or unimportant)?

D L Jones 1, J G Phillips 1, J L Bradshaw 1, R Iansek 1, J A Bradshaw 1
PMCID: PMC1014962  PMID: 8482965

Abstract

A recent study suggested that the preparation of movement direction, but not amplitude, may be selectively impaired by Parkinson's disease (PD). The authors examined the reprogramming of direction only, amplitude only, and direction and amplitude together, and included a control condition in which neither parameter was reprogrammed. The findings suggested that neither direction nor amplitude coding was differentially impaired in PD. Thus the structures affected by PD may not be uniquely involved in specifying only the direction or the amplitude of future movements; these structures probably have more complex higher-level roles.

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Selected References

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