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. 1992 Nov;55(11):1079–1083. doi: 10.1136/jnnp.55.11.1079

Pseudoaxonal Guillain-Barré syndrome: severe demyelination mimicking axonopathy. A case with pupillary involvement.

G N Fuller 1, J M Jacobs 1, P D Lewis 1, R J Lane 1
PMCID: PMC1015296  PMID: 1469406

Abstract

A patient with fulminant Guillain-Barré syndrome developed pupillary denervation, loss of all brain stem reflexes and a complete flaccid quadriparesis. Pathological studies confirmed this was due to a primarily demyelinating process and not an axonal form of Guillain-Barré syndrome.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Asbury A. K., Arnason B. G., Adams R. D. The inflammatory lesion in idiopathic polyneuritis. Its role in pathogenesis. Medicine (Baltimore) 1969 May;48(3):173–215. doi: 10.1097/00005792-196905000-00001. [DOI] [PubMed] [Google Scholar]
  2. Carroll W. M., Mastaglia F. L. 'Locked-in coma' in postinfective polyneuropathy. Arch Neurol. 1979 Jan;36(1):46–47. doi: 10.1001/archneur.1979.00500370076020. [DOI] [PubMed] [Google Scholar]
  3. Coad N. R., Byrne A. J. Guillain-Barré syndrome mimicking brainstem death. Anaesthesia. 1990 Jun;45(6):456–457. doi: 10.1111/j.1365-2044.1990.tb14333.x. [DOI] [PubMed] [Google Scholar]
  4. Cornblath D. R., Mellits E. D., Griffin J. W., McKhann G. M., Albers J. W., Miller R. G., Feasby T. E., Quaskey S. A. Motor conduction studies in Guillain-Barré syndrome: description and prognostic value. Ann Neurol. 1988 Apr;23(4):354–359. doi: 10.1002/ana.410230407. [DOI] [PubMed] [Google Scholar]
  5. Feasby T. E., Gilbert J. J., Brown W. F., Bolton C. F., Hahn A. F., Koopman W. F., Zochodne D. W. An acute axonal form of Guillain-Barré polyneuropathy. Brain. 1986 Dec;109(Pt 6):1115–1126. doi: 10.1093/brain/109.6.1115. [DOI] [PubMed] [Google Scholar]
  6. Hawkes C. H., Bryan-Smyth L. The electroencephalogram in the "locked-in" syndrome. Neurology. 1974 Nov;24(11):1015–1018. doi: 10.1212/wnl.24.11.1015. [DOI] [PubMed] [Google Scholar]
  7. Honavar M., Tharakan J. K., Hughes R. A., Leibowitz S., Winer J. B. A clinicopathological study of the Guillain-Barré syndrome. Nine cases and literature review. Brain. 1991 Jun;114(Pt 3):1245–1269. doi: 10.1093/brain/114.3.1245. [DOI] [PubMed] [Google Scholar]
  8. Jacobs J. M., Love S. Qualitative and quantitative morphology of human sural nerve at different ages. Brain. 1985 Dec;108(Pt 4):897–924. doi: 10.1093/brain/108.4.897. [DOI] [PubMed] [Google Scholar]
  9. Kanda T., Hayashi H., Tanabe H., Tsubaki T., Oda M. A fulminant case of Guillain-Barré syndrome: topographic and fibre size related analysis of demyelinating changes. J Neurol Neurosurg Psychiatry. 1989 Jul;52(7):857–864. doi: 10.1136/jnnp.52.7.857. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. McLeod J. G., Tuck R. R. Disorders of the autonomic nervous system: Part 2. Investigation and treatment. Ann Neurol. 1987 Jun;21(6):519–529. doi: 10.1002/ana.410210602. [DOI] [PubMed] [Google Scholar]
  11. Tuck R. R., McLeod J. G. Autonomic dysfunction in Guillain-Barré syndrome. J Neurol Neurosurg Psychiatry. 1981 Nov;44(11):983–990. doi: 10.1136/jnnp.44.11.983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Winer J. B., Hughes R. A. Identification of patients at risk of arrhythmia in the Guillain-Barré syndrome. Q J Med. 1988 Sep;68(257):735–739. [PubMed] [Google Scholar]

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