Abstract
Massive occurrence of polyglucosan bodies (PBs) was found within the surgically removed temporal lobe of a 34 year old woman with complex partial seizures. This peculiar feature is very unusual in neuropathological examinations of epileptogenic foci. This patient could not be included in any of the classic diseases in which PBs are found. She exhibited a localised form of glycogen storage disease.
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- Anzil A. P., Herrlinger H., Blinzinger K., Kronski D. Intraneuritic corpora amylacea. Demonstration in orbital cortex of elderly subjects by means of early postmortem brain sampling and electron microscopy. Virchows Arch A Pathol Anat Histol. 1974;364(4):297–301. doi: 10.1007/BF00432727. [DOI] [PubMed] [Google Scholar]
- Busard H. L., Renier W. O., Gabreëls F. J., Jaspar H. H., Slooff J. L., Janssen A. J., Van Haelst U. J. Lafora disease: a quantitative morphological and biochemical study of the cerebral cortex. Clin Neuropathol. 1987 Jan-Feb;6(1):1–6. [PubMed] [Google Scholar]
- Carpenter S., Karpati G. Sweat gland duct cells in Lafora disease: diagnosis by skin biopsy. Neurology. 1981 Dec;31(12):1564–1568. doi: 10.1212/wnl.31.12.1564. [DOI] [PubMed] [Google Scholar]
- Engel J., Jr, Driver M. V., Falconer M. A. Electrophysiological correlates of pathology and surgical results in temporal lobe epilepsy. Brain. 1975 Mar;98(1):129–156. doi: 10.1093/brain/98.1.129. [DOI] [PubMed] [Google Scholar]
- Gray F., Gherardi R., Marshall A., Janota I., Poirier J. Adult polyglucosan body disease (APBD). J Neuropathol Exp Neurol. 1988 Jul;47(4):459–474. doi: 10.1097/00005072-198807000-00007. [DOI] [PubMed] [Google Scholar]
- Jackson G. D., Berkovic S. F., Tress B. M., Kalnins R. M., Fabinyi G. C., Bladin P. F. Hippocampal sclerosis can be reliably detected by magnetic resonance imaging. Neurology. 1990 Dec;40(12):1869–1875. doi: 10.1212/wnl.40.12.1869. [DOI] [PubMed] [Google Scholar]
- Jensen I., Klinken L. Temporal lobe epilepsy and neuropathology. Histological findings in resected temporal lobes correlated to surgical results and clinical aspects. Acta Neurol Scand. 1976 Nov;54(5):391–414. doi: 10.1111/j.1600-0404.1976.tb04372.x. [DOI] [PubMed] [Google Scholar]
- Palmucci L., Anzil A. P., Luh S. Intra-astrocytic glycogen granules and corpora amylacea stain positively for polyglucosans: a cytochemical contribution on the fine structural polymorphism of particulate polysaccharides. Acta Neuropathol. 1982;57(2-3):99–102. doi: 10.1007/BF00685376. [DOI] [PubMed] [Google Scholar]
- RAMSEY H. J. ULTRASTRUCTURE OF CORPORA AMYLACEA. J Neuropathol Exp Neurol. 1965 Jan;24:25–39. doi: 10.1097/00005072-196501000-00003. [DOI] [PubMed] [Google Scholar]
- Robitaille Y., Carpenter S., Karpati G., DiMauro S. D. A distinct form of adult polyglucosan body disease with massive involvement of central and peripheral neuronal processes and astrocytes: a report of four cases and a review of the occurrence of polyglucosan bodies in other conditions such as Lafora's disease and normal ageing. Brain. 1980 Jun;103(2):315–336. doi: 10.1093/brain/103.2.315. [DOI] [PubMed] [Google Scholar]
- Roukema P. A. Oderkerk CH: Isolation and preliminary characterization of corpora amylacea from human brain. Psychiatr Neurol Neurochir. 1970 Mar-Apr;73(2):87–96. [PubMed] [Google Scholar]
- Yagishita S., Itoh Y., Nakano T., Amano N., Yokoi S., Hasegawa O., Tanaka T. Pleomorphic intra-neuronal polyglucosan bodies mainly restricted to the pallidium. A case report. Acta Neuropathol. 1983;62(1-2):159–163. doi: 10.1007/BF00684936. [DOI] [PubMed] [Google Scholar]