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[Preprint]. 2023 Apr 17:2023.04.12.23288492. [Version 1] doi: 10.1101/2023.04.12.23288492

Reliability and Validity of self-reported Vascular Risk Factors in a Multi-Ethnic Community Based Study of Aging and Dementia

Annie J Lee, Didi Sanchez, Dolly Reyes-Dumeyer, Adam M Brickman, Rafael A Lantigua, Badri N Vardarajan, Richard Mayeux
PMCID: PMC10153321  PMID: 37131736

ABSTRACT

INTRODUCTION

The reliability and validity of self-reported cardiovascular and cerebrovascular risk factors remains inconsistent in aging research.

METHODS

We assessed the reliability, validity, sensitivity, specificity, and percent agreement of self-reported hypertension, diabetes, and heart disease, in comparison with direct measures of blood pressure, hemoglobin A1c (HbA1c), and medication use in 1870 participants in a multiethic study of aging and dementia.

RESULTS

Reliability of self-reported for hypertension, diabetes, and heart disease was excellent. Agreement between self-reports and clinical measures was moderate for hypertension (kappa: 0.58), good for diabetes (kappa: 0.76-0.79), and moderate for heart disease (kappa: 0.45) differing slightly by age, sex, education, and race/ethnic group. Sensitivity and specificity for hypertension was 88.6%-78.1%, for diabetes was 87.7%-92.0% (HbA1c > 6.5%) or 92.7%-92.8% (HbA1c > 7%), and for heart disease was 85.8%-75.5%.

DISCUSSION

Self-reported history of hypertension, diabetes, and heart disease are reliable and valid compared to direct measurements or medication use.

Full Text Availability

The license terms selected by the author(s) for this preprint version do not permit archiving in PMC. The full text is available from the preprint server.


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