Skip to main content
Journal of Medical Genetics logoLink to Journal of Medical Genetics
. 1988 Mar;25(3):186–190. doi: 10.1136/jmg.25.3.186

The frequency of consanguineous marriage among British Pakistanis.

A Darr 1, B Modell 1
PMCID: PMC1015484  PMID: 3351906

Abstract

An enquiry answered by 100 randomly selected British Pakistani mothers in the postnatal wards of two hospitals in West Yorkshire showed that 55 were married to their first cousins, while in only 33 cases had their mother been married to her first cousin. This suggests an increasing rate of consanguineous marriage in this relatively small group, by contrast with the decreasing rate observed in some other countries. The genetic implications merit further study.

Full text

PDF

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bundey S., Webb T. P., Thake A., Todd J. A community study of severe mental retardation in the West Midlands and the importance of the fragile X chromosome in its aetiology. J Med Genet. 1985 Aug;22(4):258–266. doi: 10.1136/jmg.22.4.258. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Gatrad A. R., Read A. P., Watson G. H. Consanguinity and complex cardiac anomalies with situs ambiguus. Arch Dis Child. 1984 Mar;59(3):242–245. doi: 10.1136/adc.59.3.242. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Imaizumi Y., Shinozaki N. Frequency of consanguineous marriages in Japan: geographical variations. Jinrui Idengaku Zasshi. 1984 Sep;29(3):381–385. doi: 10.1007/BF01871253. [DOI] [PubMed] [Google Scholar]
  4. Khlat M., Halabi S., Khudr A., Der Kaloustian V. M. Perception of consanguineous marriages and their genetic effects among a sample of couples from Beirut. Am J Med Genet. 1986 Oct;25(2):299–306. doi: 10.1002/ajmg.1320250215. [DOI] [PubMed] [Google Scholar]
  5. Law H. Y., Stanier P., Williamson R., Modell B., Ward R. H., Petrou M., Old J., Farrall M. Two unusual cases of first trimester prenatal diagnosis of cystic fibrosis using DNA probes. Prenat Diagn. 1987 Mar;7(3):215–221. doi: 10.1002/pd.1970070309. [DOI] [PubMed] [Google Scholar]
  6. Modell B., Petrou M., Ward R. H., Fairweather D. V., Rodeck C., Varnavides L. A., White J. M. Effect of fetal diagnostic testing on birth-rate of thalassaemia major in Britain. Lancet. 1984 Dec 15;2(8416):1383–1386. doi: 10.1016/s0140-6736(84)92070-1. [DOI] [PubMed] [Google Scholar]
  7. Old J. M., Fitches A., Heath C., Thein S. L., Weatherall D. J., Warren R., McKenzie C., Rodeck C. H., Modell B., Petrou M. First-trimester fetal diagnosis for haemoglobinopathies: report on 200 cases. Lancet. 1986 Oct 4;2(8510):763–767. doi: 10.1016/s0140-6736(86)90296-5. [DOI] [PubMed] [Google Scholar]
  8. Rao P. S., Inbaraj S. G. Inbreeding effects on fertility and sterility in southern India. J Med Genet. 1979 Feb;16(1):24–31. doi: 10.1136/jmg.16.1.24. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Medical Genetics are provided here courtesy of BMJ Publishing Group

RESOURCES