Table 2.
Lung function parameters and BMI at baseline and after six months ETI treatment. BMI values are indicated for all adult patients whereas BMI z-Score is provided for juveniles.
| Baseline |
Follow-up |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean [t0] | SD [t0] | 95% CI [t0] lower limit | 95% CI [t0] upper limit | n | Mean [t6] | SD [t6] | 95% CI [t6] lower limit | 95% CI [t6] upper limit | n | Difference | SE | P-value | |
| FVC (%) | 86.1 | 15.2 | 82.5 | 89.8 | 69 | 91.6 | 17.6 | 87.3 | 95.9 | 67 | 5.7 | 1.57 | <0.001 |
| FEV 1 (%) | 69.3 | 21.3 | 64.2 | 74.4 | 69 | 79.4 | 21.0 | 74.3 | 84.5 | 67 | 10.0 | 1.31 | <0.001 |
| FEV1/FVC | 0.8 | 0.2 | 0.8 | 0.8 | 69 | 0.9 | 0.4 | 0.8 | 1.0 | 67 | 0.1 | 0.05 | 0.015 |
| MEF 25 (%) | 44.2 | 33.3 | 36.2 | 52.2 | 69 | 60.0 | 42.1 | 49.7 | 70.3 | 67 | 15.5 | 2.45 | <0.001 |
| sReff (%) | 184.6 | 93.2 | 161.5 | 207.7 | 65 | 144.7 | 92.5 | 121.8 | 167.6 | 65 | −36.8 | 7.92 | <0.001 |
| RV (%) | 142.9 | 51.9 | 130.1 | 155.6 | 66 | 123.3 | 34.5 | 114.7 | 131.8 | 65 | −17.7 | 4.66 | <0.001 |
| TLC (%) | 105.2 | 13.1 | 102.0 | 108.4 | 66 | 105.5 | 12.1 | 102.5 | 108.5 | 65 | 0.6 | 0.95 | 0.125 |
| RV/TLC | 1.4 | 0.5 | 1.3 | 1.5 | 66 | 1.2 | 0.3 | 1.1 | 1.2 | 65 | −0.2 | 0.05 | <0.001 |
| BMI | 21.7 | 2.8 | 20.9 | 22.5 | 52 | 22.4 | 2.8 | 21.6 | 23.2 | 51 | 0.7 | 0.39 | <0.001 |
| BMI z-Score | −0.4 | 1.2 | −1.0 | 0.3 | 17 | 0.1 | 1.0 | −0.4 | 0.6 | 17 | 0.5 | 0.001 | 0,027 |