Table 3.

Laboratory parameters at baseline and after six months ETI treatment.

Baseline						Follow-up
	Mean [t0]	SD [t0]	95% CI [t0] lower limit	95% CI [t0] upper limit	n	Mean [t6]	SD [t6]	95% CI [t6] lower limit	95% CI [t6] upper limit	n	Difference	SE	P-value
WBC (x10^3/μl)	8.9	3.2	8.1	9.6	69	6.4	2.1	5.9	6.9	68	−2.5	0.36	<0.001
HbA1c (%)	6.0	1.0	5.7	6.2	61	5.6	0.9	5.4	5.9	66	−0.3	0.08	0.0006
Kreatinin (mg/dl)	0.7	0.2	0.7	0.8	68	0.9	0.9	0.7	1.1	69	0.2	0.05	0.009
Bilirubin (total, mg/dl)	0.6	0.5	0.5	0.7	58	0.9	0.6	0.8	1.1	69	0.3	0.02	<0.001
Bilirubin (direct, mg/dl)	0.3	0.4	0.2	0.4	52	0.4	0.3	0.3	0.5	69	0.1	1.58	<0.001
AST (U/l)	25.8	9.9	23.4	28.2	69	28.2	16.1	24.3	32.1	69	2.4	2.37	0.13
ALT (U/l)	27.0	15.3	23.3	30.6	69	31.7	21.7	26.5	36.9	69	4.7	0.04	0.047
γGT (U/l)	31.9	40.9	22.0	41.8	68	35.6	57.0	21.9	49.3	69	3.6	2.6	0.177
CHE (U/l)	7.7	2.6	7.1	8.4	62	7.4	1.8	7.0	7.8	69	−0.3	0.2	0.131
GLDH (U/l)	6.8	12.0	3.2	10.5	43	5.7	6.0	4.3	7.2	67	−1.4	1.85	0.459
CRP (mg/l)	7.9	10.1	5.3	10.5	59	8.6	13.4	4.1	13.2	35	0.0	2.86	0.987
Albumin (g/l)	41.6	3.8	40.6	42.6	61	44.5	3.2	43.7	45.3	69	3.1	0.53	<0.001
IgG (g/l)	13.9	4.0	12.9	14.9	67	11.4	2.9	10.8	12.1	69	−2.5	0.27	<0.001
IgM (g/l)	1.1	0.7	0.9	1.4	26	1.2	0.7	1.0	1.3	69	−0.1	0.04	0.0589
IgE (kU/l)	187.3	340.1	99.5	275.2	60	186.9	495.9	67.7	306.0	69	18.0	50.17	0.717
IgA (g/l)	3.0	1.8	2.5	3.4	55	2.3	1.3	2.0	2.6	68	−0.6	0.09	<0.001
Albumin/Globulin ratio	3.3	1.1	3.0	3.5	59	4.2	1.2	3.9	4.5	68	0.9	0.09	<0.001
Sweat chloride (mmol/l)	95.3	21.6	88.7	102.0	44	48.6	20.1	39.7	52.6	41	−46.7	3.17	<0.001
Sodium (mmol/l)	138.1	2.1	137.7	138.7	69	139.8	2.0	139.3	140.3	67	1.6	0.32	<0.001
Chloride (mmol/l)	102.5	12.0	99.5	105.6	63	106.8	18.9	103.1	112.3	68	4.3	2.6	0.104