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. 2023 Feb 24;66(6):1057–1070. doi: 10.1007/s00125-023-05886-8

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Validation in the IMI DIRECT study. (a) Pie diagram of five clusters in the IMI DIRECT study (n=782). (b–f) Characteristics of the five type 2 diabetes clusters in the IMI DIRECT study: age, BMI, HbA_1c, HDL-cholesterol and C-peptide. Boxplot shows median, 25th percentile and 75th percentile. (g) Effect size plot of differentially expressed lncRNAs from the current study (DCS Hoorn) and the IMI DIRECT study. (h) Effect size plot of differentially expressed mRNAs from the current study (DCS Hoorn) and the IMI DIRECT study