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. 2022 Oct 1;146(3):968–976. doi: 10.1093/brain/awac357

Figure 4.

Figure 4

Immunomodulation results in decreases in antigen specific antibodies. (A) Serum antibodies to O. volvulus antigen-16 (Ov16) or (B) O. volvulus tropomyosin (OVTmy1) in two patients prior to (black bars) and after (grey bars) plasmapheresis. Total IgG antibodies specific for O. volvulus antigens are shown on the left and IgG4 antibodies are shown on the right. (C) Serum antibodies to OV16 (IgG and IgG4) and OVTmy1 (IgG and IgG4) in a patient prior to (black bars) and after (grey bars) administration of intravenous immunoglobulin (IVIg).