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. 1990 Apr;27(4):236–239. doi: 10.1136/jmg.27.4.236

Becker muscular dystrophy: correlation of deletion type with clinical severity.

A M Norman 1, N S Thomas 1, H M Kingston 1, P S Harper 1
PMCID: PMC1017024  PMID: 2325103

Abstract

Molecular deletion screening with cDNA probes from the dystrophin gene was undertaken in patients with Becker muscular dystrophy from 58 separate families. Deletions were found in 41 (71%) of these families. Thirty-four (83%) of the deletions started in the same intron near the centre of the gene, and although there was no precise correlation between clinical severity and deletion pattern, the commonest deletion pattern, which was present in 49% of all deletion families, is associated with a mild phenotype.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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