Abstract
A 14 month old girl was found to have a deletion of the whole of band 5q23. By comparing 19 other cases monosomic for a part of the 5q13-q31 segment, the constitutional 5q interstitial deletions fall into two groups: adult patients with Gardner-like symptoms and mental retardation associated with deletion 5q21-q22, and patients (mostly children) with unspecific signs and symptoms and different deletions.
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- Bodmer W. F., Bailey C. J., Bodmer J., Bussey H. J., Ellis A., Gorman P., Lucibello F. C., Murday V. A., Rider S. H., Scambler P. Localization of the gene for familial adenomatous polyposis on chromosome 5. Nature. 1987 Aug 13;328(6131):614–616. doi: 10.1038/328614a0. [DOI] [PubMed] [Google Scholar]
- Dudin G., Alexander D., Talj F., Deeb M., Musallam S., Der Kaloustian V. M. Interstitial deletion of band q12 of chromosome 5. Clin Genet. 1984 May;25(5):455–458. doi: 10.1111/j.1399-0004.1984.tb02016.x. [DOI] [PubMed] [Google Scholar]
- Dutrillaux B., Viegas-Pequignot E. High resolution R- and G-banding on the same preparation. Hum Genet. 1981;57(1):93–95. doi: 10.1007/BF00271176. [DOI] [PubMed] [Google Scholar]
- Herrera L., Kakati S., Gibas L., Pietrzak E., Sandberg A. A. Gardner syndrome in a man with an interstitial deletion of 5q. Am J Med Genet. 1986 Nov;25(3):473–476. doi: 10.1002/ajmg.1320250309. [DOI] [PubMed] [Google Scholar]
- Leppert M., Dobbs M., Scambler P., O'Connell P., Nakamura Y., Stauffer D., Woodward S., Burt R., Hughes J., Gardner E. The gene for familial polyposis coli maps to the long arm of chromosome 5. Science. 1987 Dec 4;238(4832):1411–1413. doi: 10.1126/science.3479843. [DOI] [PubMed] [Google Scholar]
- Rivera H., Rolón A., Sánchez-Corona J., Cantú J. M. De novo t(4;5)(q3100;q2200) with del(5)(q1500q2200). Tentative delineation of a 5q monosomy syndrome and assignment of the critical segment. Clin Genet. 1985 Jan;27(1):105–109. doi: 10.1111/j.1399-0004.1985.tb00193.x. [DOI] [PubMed] [Google Scholar]
- Van den Berghe H., Vermaelen K., Mecucci C., Barbieri D., Tricot G. The 5q-anomaly. Cancer Genet Cytogenet. 1985 Jul;17(3):189–255. doi: 10.1016/0165-4608(85)90016-0. [DOI] [PubMed] [Google Scholar]
- Yung J. F., Williamson N., Salafsky I., Hoo J. J. Deletion of band 5q21 in association with a de novo translocation involving 2p and 5q. J Med Genet. 1988 Aug;25(8):570–572. doi: 10.1136/jmg.25.8.570. [DOI] [PMC free article] [PubMed] [Google Scholar]