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. 1990 Nov;27(11):683–687. doi: 10.1136/jmg.27.11.683

Theoretical considerations on germline mosaicism in Duchenne muscular dystrophy.

T Grimm 1, B Müller 1, C R Müller 1, M Janka 1
PMCID: PMC1017258  PMID: 2277383

Abstract

A newly formulated mutation selection equilibrium for lethal X linked recessive traits such as Duchenne muscular dystrophy is presented, which allows for both male and female germline mosaicism. Estimates of the additional parameters used are given, thus allowing the incorporation of germline mosaicism into the calculation of genetic risks.

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Selected References

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