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. 2023 Apr 23;5:100126. doi: 10.1016/j.bioflm.2023.100126

Table 1.

Novel approaches against Candida biofilms.

Approach Main thrust/techniques Representative references
Screening Chemical Libraries Identification of new compounds with anti-biofilm activity, alone or in combination 51, 52, 55, 56
High throughput screening (HTS)
Turbinmicin Produced by the microbiome of a marine animal 57, 58
Inhibits extracellular vesicle-delivered biofilm matrix
EntV Antifungal peptide produced by E. faecalis 60
Drug Repurposing Search for new therapeutic indications for existing drugs 68
Screening Repurposing libraries
Nanotechnology Nanomaterials, nanoparticles or nanoantibiotics 76, 78
Size of less than 100 nm in at least one of their three dimensions
Potent anti-biofilm activity, including against mixed biofilms
Othera Antimicrobial peptides 87–102
Targeting extracellular DNA
Probiotics
Hsp 90 inhibition
Modulators of quorum-sensing
Photodynamic therapy (PDT)
Catheter locks
Surface coatings
Inhibition of dispersion
a

this list is not all inclusive.