Table 7. Comparison of side effects of trials NCT01586260, NCT02395666* with those of NCT02559778**.
ALT: alanine transaminase; AST: aspartate transaminase; INR: international normalized ratio
| Side effect | (NCT01586260, NCT02395666) (n=140) [41] | (NCT02559778) (n=20) [57] |
| Anemia | 6 | 10 |
| Neutrophil count decrease | 11 | 10 |
| Platelet count decrease | 2 | 14 |
| Febrile neutropenia | - | 11 |
| White blood cell decrease | 3 | 7 |
| Abdominal pain | 1 | - |
| Agitation | 1 | - |
| Alopecia | 2 | - |
| ALT elevation | 12 | 1 |
| AST elevation | 9 | 1 |
| Alkaline phosphatase elevation | 1 | - |
| Anorexia | 1 | 1 |
| Cellulitis | - | 1 |
| Dehydration | - | 1 |
| Diarrhea | 7 | 1 |
| Epistaxis | - | 2 |
| Fever | 4 | - |
| Hearing loss | 6 | - |
| Hypoglycemia | 1 | - |
| Hypokalemia | 2 | 6 |
| Hyponatremia | - | 3 |
| Hypophosphatemia | - | 5 |
| Infection (other) | 3 | 4 |
| Infection, middle ear | 6 | - |
| INR elevated | 1 | - |
| Insomnia | 1 | - |
| Nausea | - | 4 |
| Pain | 2 | - |
| Post-nasal drip | 1 | - |
| Rash | 3 | - |
| Sepsis | - | 3 |
| Skin infection | - | 1 |
| Thromboembolic event | - | 1 |
| Vomiting | 1 | 3 |
| Weight gain | 1 | - |
| Weight loss | - | 1 |