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. 1971 Mar;26(2):212–218. doi: 10.1136/thx.26.2.212

Primary intrapulmonary neurogenic sarcoma with hypertrophic pulmonary osteoarthropathy and asbestosis

P K Caves 1,1, J Jacques 1
PMCID: PMC1019129  PMID: 5576539

Abstract

A case of primary intrapulmonary neurogenic sarcoma with hypertrophic pulmonary osteoarthropathy and asbestosis is described. The essential histological features of this rare tumour are detailed, and the five authentic cases previously reported are reviewed. The pathogenesis of hypertrophic pulmonary osteoarthropathy and its occurrence in this case are discussed. After surgical removal of the tumour recurrence appeared in the chest within six months. It responded poorly to radiotherapy, and death from metastases occurred 16 months after operation.

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Selected References

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  1. BARTLEY T. D., AREAN V. M. INTRAPULMONARY NEUROGENIC TUMORS. J Thorac Cardiovasc Surg. 1965 Jul;50:114–123. [PubMed] [Google Scholar]
  2. BENOIT H. W., Jr, ACKERMAN L. V. Solitary pleural mesotheliomas. J Thorac Surg. 1953 Apr;25(4):346–357. [PubMed] [Google Scholar]
  3. BERMAN B. PULMONARY HYPERTROPHIC OSTEOARTHROPATHY. Arch Intern Med. 1963 Dec;112:947–953. doi: 10.1001/archinte.1963.03860060171019. [DOI] [PubMed] [Google Scholar]
  4. DIVELEY W., DANIEL R. A., Jr Primary solitary neurogenic tumors of the lung. J Thorac Surg. 1951 Feb;21(2):194–201. [PubMed] [Google Scholar]
  5. ELMES P. C., MCCAUGHEY W. T., WADE O. L. DIFFUSE MESOTHELIOMA OF THE PLEURA AND ASBESTOS. Br Med J. 1965 Feb 6;1(5431):350–353. doi: 10.1136/bmj.1.5431.350. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. FLAVELL G. Reversal of pulmonary hypertrophic osteoarthropathy by vagotomy. Lancet. 1956 Feb 11;270(6911):260–262. doi: 10.1016/s0140-6736(56)91186-2. [DOI] [PubMed] [Google Scholar]
  7. GINSBURG J., BROWN J. B. Increased oestrogen excretion in hypertrophic pulmonary osteoarthropathy. Lancet. 1961 Dec 9;2(7215):1274–1276. doi: 10.1016/s0140-6736(61)91139-4. [DOI] [PubMed] [Google Scholar]
  8. GINSBURG J. Observations on the peripheral circulation in hypertrophic pulmonary osteoarthropathy. Q J Med. 1958 Jul;27(107):335–352. [PubMed] [Google Scholar]
  9. HOLLING H. E., BRODEY R. S., BOLAND H. C. Pulmonary hypertrophic osteoarthropathy. Lancet. 1961 Dec 9;2(7215):1269–1274. doi: 10.1016/s0140-6736(61)91138-2. [DOI] [PubMed] [Google Scholar]
  10. HOLLING H. E., DANIELSON G. K., HAMILTON R. W., BLAKEMORE W. S., BRODEY R. S. HYPERTROPHIC PULMONARY OSTEOARTHROPATHY. J Thorac Cardiovasc Surg. 1963 Sep;46:310–321. [PubMed] [Google Scholar]
  11. Holling H. E. Pulmonary hypertrophic osteoarthropathy. Ann Intern Med. 1967 Jan;66(1):232–234. doi: 10.7326/0003-4819-66-1-232. [DOI] [PubMed] [Google Scholar]
  12. Hollis W. C. Hypertrophic osteoarthropathy secondary to upper-gastrointestinal-tract neoplasm. Case report and review. Ann Intern Med. 1967 Jan;66(1):125–130. doi: 10.7326/0003-4819-66-1-125. [DOI] [PubMed] [Google Scholar]
  13. Hourihane D. O., Lessof L., Richardson P. C. Hyaline and calcified pleural plaques as an index of exposure to asbestos. Br Med J. 1966 Apr 30;1(5495):1069–1074. doi: 10.1136/bmj.1.5495.1069. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. NEILSON D. B. Primary intrapulmonary neurogenic sarcoma. J Pathol Bacteriol. 1958 Oct;76(2):419–430. doi: 10.1002/path.1700760210. [DOI] [PubMed] [Google Scholar]
  15. Owen W. G. Mesothelial tumors and exposure to asbestos dust. Ann N Y Acad Sci. 1965 Dec 31;132(1):674–679. doi: 10.1111/j.1749-6632.1965.tb41144.x. [DOI] [PubMed] [Google Scholar]
  16. PETRIAT A., CORNET L., LEGER H., CASTAING R., TESSIER R. Neurinome primitif intra-pulmonaire. Presse Med. 1953 Nov 18;61(74):1526–1528. [PubMed] [Google Scholar]
  17. SEMPLE T., McCLUSKIE R. A. Generalized hypertrophic osteoarthropathy in association with bronchial carcinoma; a review, based on 24 cases. Br Med J. 1955 Mar 26;1(4916):754–759. doi: 10.1136/bmj.1.4916.754. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. TRIVEDI S. A. Neurilemmoma of the diaphragm causing severe hypertrophic pulmonary osteoarthropathy. Br J Tuberc Dis Chest. 1958 Jul;52(3):214–217. doi: 10.1016/s0366-0869(58)80133-1. [DOI] [PubMed] [Google Scholar]
  19. VOGL A., BLUMENFELD S., GUTNER L. B. Diagnostic significance of pulmonary hypertrophic osteoarthropathy. Am J Med. 1955 Jan;18(1):51–65. doi: 10.1016/0002-9343(55)90205-9. [DOI] [PubMed] [Google Scholar]
  20. WAGNER J. C., SLEGGS C. A., MARCHAND P. Diffuse pleural mesothelioma and asbestos exposure in the North Western Cape Province. Br J Ind Med. 1960 Oct;17:260–271. doi: 10.1136/oem.17.4.260. [DOI] [PMC free article] [PubMed] [Google Scholar]

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