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. 1995 May;50(5):565–566. doi: 10.1136/thx.50.5.565

Bilateral sequential lung transplantation for end stage septic lung disease.

A Hasan 1, P A Corris 1, M Healy 1, N Wrightson 1, A D Gascoigne 1, D A Waller 1, I Wilson 1, C J Hilton 1, F K Gould 1, J Forty 1, et al.
PMCID: PMC1021232  PMID: 7597674

Abstract

BACKGROUND-- Bilateral sequential lung transplantation (BSLT) has been widely adopted as an alternative to combined heart and lung transplantation for the management of end stage septic lung disease in many transplant centres. METHODS-- A retrospective review was undertaken of the first 32 consecutive patients with septic lung disease to undergo BSLT at the Freeman Hospital. RESULTS-- Between April 1988 and October 1994 32 patients underwent BSLT. Survival at 30 days was 85% and actuarial survival at one year was 70%. Improved pulmonary function was seen in all surviving patients. CONCLUSION-- BSLT for septic lung disease offers comparable survival to heart-lung transplantation, with excellent functional results. Long term results may be superior because the disadvantages of transplanting the heart are avoided.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Burke C. M., Glanville A. R., Theodore J., Robin E. D. Lung immunogenicity, rejection, and obliterative bronchiolitis. Chest. 1987 Sep;92(3):547–549. doi: 10.1378/chest.92.3.547. [DOI] [PubMed] [Google Scholar]
  2. Burke C. M., Glanville A. R., Theodore J., Robin E. D. Lung immunogenicity, rejection, and obliterative bronchiolitis. Chest. 1987 Sep;92(3):547–549. doi: 10.1378/chest.92.3.547. [DOI] [PubMed] [Google Scholar]
  3. Dawkins K. D., Jamieson S. W., Hunt S. A., Baldwin J. C., Burke C. M., Morris A., Billingham M. E., Theodore J., Oyer P. E., Stinson E. B. Long-term results, hemodynamics, and complications after combined heart and lung transplantation. Circulation. 1985 May;71(5):919–926. doi: 10.1161/01.cir.71.5.919. [DOI] [PubMed] [Google Scholar]
  4. Forty J., Hasan A., Gould F. K., Corris P. A., Dark J. H. Single lung transplantation with simultaneous contralateral pneumonectomy for cystic fibrosis. J Heart Lung Transplant. 1994 Jul-Aug;13(4):727–730. [PubMed] [Google Scholar]
  5. Inui K., Schäfers H. J., Aoki M., Becker V., Ongsiek B., Kemnitz J., Haverich A., Borst H. G. Bronchial circulation after experimental lung transplantation. The effect of long-term administration of prednisolone. J Thorac Cardiovasc Surg. 1993 Mar;105(3):474–479. [PubMed] [Google Scholar]
  6. Inui K., Schäfers H. J., Aoki M., Becker V., Ongsiek B., Kemnitz J., Haverich A., Borst H. G. Bronchial circulation after experimental lung transplantation. The effect of long-term administration of prednisolone. J Thorac Cardiovasc Surg. 1993 Mar;105(3):474–479. [PubMed] [Google Scholar]
  7. Jones K., Higenbottam T., Wallwork J. Successful heart-lung transplantation for cystic fibrosis. Chest. 1988 Mar;93(3):644–645. doi: 10.1378/chest.93.3.644. [DOI] [PubMed] [Google Scholar]
  8. Morgan-Hughes N. J., Corris P. A., Healey M. D., Dark J. H., McComb J. M. Cardiovascular and respiratory effects of adenosine in humans after pulmonary denervation. J Appl Physiol (1985) 1994 Feb;76(2):756–759. doi: 10.1152/jappl.1994.76.2.756. [DOI] [PubMed] [Google Scholar]
  9. Novick R. J., Kaye M. P., Patterson G. A., Andréassian B., Klepetko W., Menkis A. H., McKenzie F. N. Redo lung transplantation: a North American-European experience. J Heart Lung Transplant. 1993 Jan-Feb;12(1 Pt 1):5–16. [PubMed] [Google Scholar]
  10. Pasque M. K., Cooper J. D., Kaiser L. R., Haydock D. A., Triantafillou A., Trulock E. P. Improved technique for bilateral lung transplantation: rationale and initial clinical experience. Ann Thorac Surg. 1990 May;49(5):785–791. doi: 10.1016/0003-4975(90)90023-y. [DOI] [PubMed] [Google Scholar]
  11. Pasque M. K., Cooper J. D., Kaiser L. R., Haydock D. A., Triantafillou A., Trulock E. P. Improved technique for bilateral lung transplantation: rationale and initial clinical experience. Ann Thorac Surg. 1990 May;49(5):785–791. doi: 10.1016/0003-4975(90)90023-y. [DOI] [PubMed] [Google Scholar]
  12. Ramirez J. C., Patterson G. A., Winton T. L., de Hoyos A. L., Miller J. D., Maurer J. R. Bilateral lung transplantation for cystic fibrosis. The Toronto Lung Transplant Group. J Thorac Cardiovasc Surg. 1992 Feb;103(2):287–294. [PubMed] [Google Scholar]
  13. Reitz B. A., Wallwork J. L., Hunt S. A., Pennock J. L., Billingham M. E., Oyer P. E., Stinson E. B., Shumway N. E. Heart-lung transplantation: successful therapy for patients with pulmonary vascular disease. N Engl J Med. 1982 Mar 11;306(10):557–564. doi: 10.1056/NEJM198203113061001. [DOI] [PubMed] [Google Scholar]
  14. Sharples L. D., Scott J. P., Dennis C., Higenbottam T. W., Stewart S., Wreghitt T., Large S. R., Wells F. C., Wallwork J. Risk factors for survival following combined heart-lung transplantation. The first 100 patients. Transplantation. 1994 Jan;57(2):218–223. doi: 10.1097/00007890-199401001-00011. [DOI] [PubMed] [Google Scholar]
  15. Shennib H., Noirclerc M., Ernst P., Metras D., Mulder D. S., Giudicelli R., Lebel F., Dumon J. F. Double-lung transplantation for cystic fibrosis. The Cystic Fibrosis Transplant Study Group. Ann Thorac Surg. 1992 Jul;54(1):27–32. doi: 10.1016/0003-4975(92)91135-v. [DOI] [PubMed] [Google Scholar]

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