Figure 1.

Exposure of the tooth pulp in the left mandibular molar of rats produces ipsilateral orofacial allodynia for up to 2 weeks. Effect of sham procedure or pulp exposure on mechanical withdrawal threshold on the ipsilateral side (A,C) or contralateral side (B,D). Orofacial sensitivity was measured with Von Frey filaments prior to pulp exposure procedure and again 1, 7, and 14 days post-exposure. N = 10/group. Ipsilateral and contralateral data are collected from the same rats. * p < 0.05 compared with baseline.