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(a) Sketch of the (Poly-1/ICMV) multilayers decorated microneedle surfaces. (b) Microneedle application into the skin. (c) Hydrolytic degradation of Poly-1 releasing the ICMV. (d) ICMV delivery to skin APCs. Reprinted with permission from DeMuth et al. [92]. Copyright (2012) American Chemical Society.
