American Heart Association EPI|Lifestyle Scientific Sessions: 2022 Meeting Highlights

Elisabeth L P Sattler; Oluwabunmi Ogungbe; Amelia S Wallace; Zahra Aryan; Noelle Castilla‐Ojo; Jin Dai; Ileana De Anda‐Duran; Kathryn Foti; Charles A German; Eric T Hyde; Scott R Jafarian‐Kerman; Karla N Kendrick; Ben King; Adam Edward Lang; Olive Tang; Ruth‐Alma Turkson‐Ocran; Luis A Rodriguez; Frances M Wang; Mingyu Zhang, PhD; Marie‐France Hivert; Pamela L Lutsey

doi:10.1161/JAHA.122.028695

. 2023 Apr 12;12(8):e028695. doi: 10.1161/JAHA.122.028695

American Heart Association EPI|Lifestyle Scientific Sessions: 2022 Meeting Highlights

Elisabeth L P Sattler ^1,^2,^*,^✉, Oluwabunmi Ogungbe ^3,^4,^*, Amelia S Wallace ^5,^6,^*, Zahra Aryan ⁷, Noelle Castilla‐Ojo ⁸, Jin Dai ⁹, Ileana De Anda‐Duran ¹⁰, Kathryn Foti ¹¹, Charles A German ¹², Eric T Hyde ¹³, Scott R Jafarian‐Kerman ¹⁴, Karla N Kendrick ¹⁵, Ben King ¹⁶, Adam Edward Lang ^17,¹⁸, Olive Tang ^5,^6,¹⁹, Ruth‐Alma Turkson‐Ocran ⁸, Luis A Rodriguez ²⁰, Frances M Wang ^5,⁶, Mingyu Zhang PhD ^5,^6,²¹, Marie‐France Hivert ^21,²², Pamela L Lutsey ²³

^¹Department of Clinical and Administrative Pharmacy, College of Pharmacy, University of Georgia, GA, Athens, USA

^²Department of Nutritional Sciences, College of Family and Consumer Sciences, University of Georgia, GA, Athens, USA

^³Johns Hopkins University School of Nursing, MD, Baltimore, USA

^⁴Johns Hopkins University School of Medicine, MD, Baltimore, USA

^⁵Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, MD, Baltimore, USA

^⁶Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, MD, Baltimore, USA

^⁷Department of Medicine, Rutgers New Jersey Medical School, NJ, Newark, USA

^⁸Beth Israel Deaconess Medical Center, Harvard Medical School, MA, Boston, USA

^⁹Department of Epidemiology, Fielding School of Public Health, University of California, CA, Los Angeles, USA

^¹⁰Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, LA, New Orleans, USA

^¹¹Department of Epidemiology, University of Alabama at Birmingham School of Public Health, AL, Birmingham, USA

^¹²Department of Medicine, University of Chicago, IL, Chicago, USA

^¹³Herbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, CA, La Jolla, USA

^¹⁴Department of Internal Medicine, Hackensack Meridian Raritan Bay Medical Center, NJ, Perth Amboy, USA

^¹⁵Winchester Hospital, MA, Winchester, USA

^¹⁶Department of Health Systems and Population Health Sciences, Tilman J Fertitta Family College of Medicine, University of Houston, TX, Houston, USA

^¹⁷Department of Primary Care, McDonald Army Health Center, VA, Fort Eustis, USA

^¹⁸Department of Family Medicine and Population Health, Virginia Commonwealth University School of Medicine, VA, Richmond, USA

^¹⁹Johns Hopkins University School of Medicine, MD, Baltimore, USA

^²⁰Division of Research, Kaiser Permanente Northern California, CA, Oakland, USA

^²¹Department of Population Medicine, Harvard Pilgrim Health Care Institute, Harvard Medical School, MA, Boston, USA

^²²Diabetes Unit, Massachusetts General Hospital, MA, Boston, USA

^²³Division of Epidemiology and Community Health, University of Minnesota, MN, Minneapolis, USA

^*

Correspondence to: Elisabeth L. P. Sattler, PhD, RPh, Department of Clinical and Administrative Pharmacy, College of Pharmacy, Department of Nutritional Sciences, College of Family and Consumer Sciences, University of Georgia, 250 W. Green St, Athens, GA 30602. Email: lilian@uga.edu

^*

E. L. P. Sattler, O. Ogungbe, and A. S. Wallace are co‐first authors.

^✉

Corresponding author.

PMCID: PMC10227275 PMID: 37042282

The 2022 American Heart Association (AHA) Council on Epidemiology and Prevention and Council on Lifestyle and Cardiometabolic Health sponsored EPI|Lifestyle Scientific Sessions were held from March 1, 2022 to March 4, 2022 in Chicago, IL. This annual AHA subspecialty conference represents a joint platform for the Council on Lifestyle and Cardiometabolic Health (Lifestyle) and the Council on Epidemiology and Prevention (EPI) to promote population science around cardiovascular health and the prevention of heart diseases and stroke. The 2022 conference theme was “Green World, Heart‐Healthy Living” and focused on the links between cardiovascular health, food sustainability, and the environment. The conference hosted an international audience of researchers, offering the opportunity for networking and in‐depth discussion. Despite the ongoing COVID‐19 pandemic, conference participation was high, with nearly 500 scientists, clinicians, public health officials, and trainees attending. The conference hosted >300 poster presentations (including e‐posters), 13 moderated poster sessions with 73 presentations, and 10 oral abstract sessions with 68 presentations. The 2022 meeting was chaired by Dr Pamela Lutsey from the University of Minnesota who represented the EPI Council and Dr Marie‐France Hivert from Harvard Medical School representing the Lifestyle Council. The vice‐chairs were Drs. Alvaro Alonso from Emory University (EPI Council) and Monica Serra from the University of Texas Health in San Antonio (Lifestyle Council).

AHA'S CONTINUED INVESTMENT IN HEALTH EQUITY AND SOCIAL JUSTICE

In his opening remarks, AHA president (2021–2022) and past chair of the AHA Council on Epidemiology and Prevention Dr Donald Lloyd‐Jones, from Northwestern University recognized the continued importance of addressing the impacts of structural racism and social determinants on cardiovascular health. He highlighted AHA's grassroots advocacy network—You're the Cure—and their continued investment in health equity and social justice research through funding of Strategically Focused Health Equity Research Networks focused on Disparities in Maternal–Infant Health Outcomes ($20 million), the Prevention of Hypertension ($20 million), and The Science of Diverse Enrollment in Clinical Trials ($4.3 million).

KEYNOTE SESSIONS

The opening keynote session, entitled “Air Pollution, Green World and Healthy Heart Living,” featured Dr Sanjay Rajagopalan from the Case Western Reserve University and Dr Christopher Gardner from Stanford University. The conference chairs, Drs. Lutsey and Hivert, moderated the session. Dr Rajagopalan began with an overview of ways in which climate change may impact cardiovascular health, then presented a summary of the intersection between pollution and cardiovascular health and highlighted the need for multidisciplinary efforts to combat climate change for both human and planetary health. Additional information about personal measures that can be taken are provided in a 2020 AHA scientific statement focused on personal‐level protective actions against particulate matter air pollution exposure, of which Dr Rajagopalan was first author. ¹ Dr Gardner followed with an overview of the relationship between food sustainability and cardiovascular health. To preserve planetary resources for the future, he argued that structural‐level changes are needed in agricultural production, and that individual‐level changes are needed to reduce food waste and change dietary patterns. He suggested that while we should move towards “plant‐forward” primarily plant‐based diets, which can also incorporate nonplant‐based items. Additionally, he stressed that plant‐forward diets can and should be “unapologetically delicious” and invited public health messaging to highlight the pleasure and flavorful choices of heart‐healthy foods. His talk echoed a recent AHA scientific statement emphasizing the need to create an environment that facilitates adherence to heart‐healthy dietary patterns. ²

MEMORIAL LECTURES AND SPECIAL SESSIONS

David Kritchevsky Memorial Lecture

The David Kritchevsky Memorial Lectureship honors the legacy of Dr Kritchevsky, whose research had a substantial influence on our knowledge of the role of diet in the pathophysiology of atherosclerosis. ³ The 2022 honoree was Dr Alice Lichtenstein, Director of the Cardiovascular Laboratory at the Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging and professor of Nutrition Science and Policy at Tufts University. Her talk, entitled “Nutrition in the 21st Century: Getting our Bearings,” discussed the 2021 AHA Dietary Guidance to improve Cardiovascular Health, ² which was a multidisciplinary effort sponsored by the AHA Councils on Lifestyle and Cardiometabolic Health; Atherosclerosis, Thrombosis and Vascular Biology; Cardiovascular Radiology and Intervention; Clinical Cardiology; and the Stroke Council. In her talk, Dr Lichtenstein highlighted the importance of evidence‐based, heart‐healthy dietary patterns and their elements. She stressed that heart‐healthy dietary patterns are adaptable to an array of preferences and lifestyles and help promote the goal of sustainability.

Richard D. Remington Methodology Lecture

Dr Miguel Hernan, Director of the CAUSALab and Professor of Biostatistics and Epidemiology at Harvard University, delivered the Richard D. Remington Methodology Lecture, entitled “Do Lifestyle Interventions Work? The Promises and Challenges of Causal Inference from Cohort Studies.” Dr Hernan highlighted the need for causal knowledge about comparative effectiveness and safety in decision‐making. However, because trials may be costly, unethical, impractical, or untimely, he explained that it is important to use cohort data well. While data from observational cohorts may have issues because of measurement error and confounding, the data can be improved by linking it to other existing data sources, including biobanks, and collecting data that complements traditional self‐reported data.

William B. Kannel, MD Memorial Lectureship in Preventive Cardiology

Dr Dan Roden, Director of the Oates Institute for Experimental Therapeutics, Senior Vice President for Personalized Medicine, and Professor of Medicine at Vanderbilt University Medical Center provided the 2022 William B. Kannel Memorial Lecture, which honors Dr Kannel's contributions to the field of cardiovascular epidemiology. ⁴ Dr Roden's talk, entitled “Big Data and Little Data Approaches to Personalizing Medicine,” focused on using genomics and genetics data to help shape individualized care.

AHA Scientific Updates

The AHA Scientific Updates session featured the recently published Heart Disease and Stroke Statistics, Scientific Statements, and Initiatives from the AHA. The moderators of this session were Dr Kiarri Kershaw, from Northwestern University, and Dr Elaine Urbina from the University of Cincinnati.

Dr Connie Tsao, from Harvard University, presented the 2022 AHA Report on Heart Disease and Stroke Statistics on behalf of the AHA Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee. ⁵ The report provides up‐to‐date statistics on heart disease, stroke, and cardiovascular disease (CVD) risk factors in the AHA's My Life Check—Life's Simple 7, and the latest data on major clinical heart and circulatory disease conditions and associated outcomes. The latest data included in the report highlight that 2 million CVD events could be prevented annually if the US adult population would attain high CVH, and that if all US adults showed a slight improvement from a low to a moderate level of CVH, about 1.2 million CVD events could be prevented annually.

Dr Véronique Roger from the National Heart, Lung, and Blood Institute (NHLBI) presented early experiences with the Research Goes Red registry. ⁶ This registry, launched by the AHA and Verily in 2019, is an online platform that engages women and provides data about women's cardiovascular health to guide future research priorities. Planned future directions highlighted by Dr Roger include increasing the reach and diversity of participants and engaging researchers to leverage this platform to conduct high‐quality patient‐centered research.

Dr Bethany Barone Gibbs, from the University of Pittsburgh, introduced the recent AHA Scientific Statement on supporting physical activity in populations during life events and transitions. ⁷ This Scientific Statement provides a synthesis of data on changes in physical activity and sedentary behavior during life events and transitions such as pregnancy, parenting, retirement, death of a loved one, or major illness. Additionally, it provides guidance for health care professionals to identify such changes and promote physical activity during these times of life events and transitions.

Dr Stephen Juraschek, from Harvard University, introduced GoFresh (Groceries for Black Residents of Urban Food Deserts), a study which is a part of the AHA‐funded Health Equity Research Network, the Addressing Social Determinants to Prevent Hypertension (also known as RESTORE) Network. ⁸ Their team plans to test the effectiveness of an intervention facilitating virtually ordered, home‐delivered groceries meeting the Dietary Approaches to Stop Hypertension eating pattern and coaching by dietitians in lowering blood pressure among Black adults with untreated high blood pressure who live in neighborhoods considered food deserts in the Boston area. Future study optimization steps include identifying subgroups that will benefit the most from these interventions.

Dr Joshua Joseph, from The Ohio State University, presented the recent AHA Scientific Statement on the comprehensive management of cardiovascular risk factors for adults with type 2 diabetes (T2D). ⁹ This statement provides updates to the 2015 AHA/American Diabetes Association Scientific Statement ¹⁰ and emphasizes the importance of lifestyle interventions, pharmacological therapy, and surgical interventions to combat the epidemic of obesity and metabolic syndrome, precursors of prediabetes, diabetes, and CVDs.

American Society for Preventive Cardiology Annual Debate

The topic of the annual American Society of Preventive Cardiology Annual Debate was “Primordial Prevention: Is Pharmacological Intervention in Early Life Worth the Risk?” The session was moderated by Dr Alvaro Alonso from Emory University and Dr Laura Rasmussen‐Torvik, from Northwestern University. Dr Claudia Fox, associate professor of pediatrics at University of Minnesota advocated for pharmacological interventions in primordial prevention, while Dr Laura Hayman, professor of nursing at the University of Massachusetts Boston advocated for lifestyle‐based interventions.

Dr Fox started the debate by highlighting the obesity epidemic in children, especially during the COVID‐19 pandemic. She discussed prior studies describing the link between childhood obesity and adulthood obesity and cardiometabolic disease. She defined obesity as a disease rather than a behavior and one that requires early‐life intervention. She highlighted new effective medications on the market and in development and asserted that these treatments address early physiological risk factors more effectively than lifestyle interventions. She also shared important clinical perspectives, as many families with children with obesity feel ‘shamed’ for multiple years before being offered pharmacologic options that address the biology of weight regulation.

Dr Hayman responded with a case for nonpharmacological primordial prevention in children. She shared results demonstrating the value of early dietary and physical activity intervention on childhood metabolic risk profiles. She emphasized that the long‐term, potential harms of pharmacological intervention for primordial prevention in children and adolescents are not well‐understood. With much audience engagement, Drs. Fox and Hayman agreed on the need to tailor primordial prevention. Lifestyle interventions may suffice for children who can adopt them, but pharmaceuticals may be necessary for those who are at the highest risk of developing cardiovascular complications early in life.

ORAL ABSTRACT PRESENTATIONS

In addition to the keynote and named lecture sessions, oral abstracts, and moderated posters were presented on a range of topics.

Social Determinants and Health Disparities

In the Social Determinants and Health Disparities session, moderated by Dr Nrupen Bhavsar from Duke University and Dr Mahasin Mujahid from the University of California, Berkeley, presenters highlighted findings from diverse study populations focused on the measurement and implications of individual and neighborhood factors for disparities in cardiovascular health.

Yuemeng Li from the University of Washington leveraged data from the National Health Interview Survey to highlight variability in levels of acculturation among immigrants from Asian subgroups and the association of higher acculturation with worse cardiovascular health among Asian subpopulations. ¹¹

Dr Michael Bancks from Wake Forest University demonstrated the association between self‐reported experiences of discrimination in multiple domains and the risk of dementia over 17 years in the MESA (Multi‐Ethnic Study of Atherosclerosis) study. This association remained robust even after adjustment for demographic, socioeconomic, and clinical risk factors. ¹²

Dr Jingchuan Guo from the University of Florida found racial and geographic disparities in prescribing novel cardioprotective medications, including sodium‐glucose co‐transporter 2 inhibitors and glucagon‐like peptide 1 agonists. Both neighborhood‐ and individual‐level factors were associated with profound prescribing differences in the OneFlorida+ cohort. ¹³

Next, Joshua Garfein from the University of Pittsburgh shared their work using Optum's deidentified Clinformatic database They found stark racial and ethnic differences in engagement with cardiac rehabilitation and the modification of this relationship by household income. ¹⁴

Andrew Johns from Tulane University presented findings highlighting the disconnect between perceived neighborhood disorder compared with an objective 38‐domain score among a convenience sample of participants in the Healthy Neighborhoods Project in New Orleans, LA.

Finally, Dr Nwabunie Nawana from Houston Methodist Research Institute shared findings on the association between higher neighborhood socioeconomic disadvantage, as measured by the area deprivation index, and higher prevalence of class III obesity (body mass index [BMI] ≥ 40 kg/m²) in the Houston Methodist outpatient population. ¹⁵

Diabetes and Obesity

The 2022 Diabetes and Obesity session was moderated by Dr Liliana Aguayo from Emory University and Dr Elizabeth Selvin from Johns Hopkins University.

Dr Lauren Berube from New York University presented findings that adults with prediabetes randomized to a personalized diet had greater reductions in energy intake from carbohydrates and sugars than those assigned to a standard diet in the first 3 months, but dietary changes were similar by 6 months. ¹⁶

An analysis of the CHAMPION trial (Randomized Trial of a Healthy Weight Intervention for Youth With Mental Illness), a weight control intervention for children with serious emotional disturbances, was presented by Dr Nae‐Yuh Wang on behalf of Dr Gail Daumit from Johns Hopkins University. The study found that BMI Z‐scores in the active intervention arm decreased substantially compared with the control arm, even during the COVID‐19 pandemic. ¹⁷

Next, Dr Michael Bancks from Wake Forest University presented an analysis from the Look AHEAD (Action for Health in Diabetes) trial that evaluated the effects of an intensive lifestyle intervention, compared with a control group receiving diabetes support and education, to reduce CVD risk among participants stratified by hemoglobin A1c at baseline. The intensive lifestyle intervention, compared with the control, was associated with higher CVD risk only among those with high hemoglobin A1c at baseline hemoglobin A1c ≥8.7%. ¹⁸

Presenting on behalf of Dr Patricia Chavez, Dr Ayana April‐Sanders from the Albert Einstein College of Medicine and colleagues analyzed data from the Echocardiographic Study of Latinos‐2 and found that early stages of worsening glucose homeostasis (ie, changing from normal to prediabetic) were associated with adverse cardiac structural and functional changes. ¹⁹

Based on data from Black Caribbean men in the Tobago Health Study, Dr Megan Marron from the University of Pittsburgh found that displacement of sedentary time with light physical activity, but not moderate‐to‐vigorous physical activity, was significantly associated with a less harmful distribution of ectopic fat. ²⁰

Finally, Aylin Memili from the University of North Carolina used 25 years of data from the ARIC (Atherosclerosis Risk in Communities) study and latent class mixed models to derive 4 subclasses of longitudinal measures of obesity. The Genome‐Wide Association Study (GWAS) of the 4 obesity subclasses showed unique genetic architecture, suggesting that CVD risk may be heterogeneous across populations with obesity. ²¹

Recent Advances in Omics

This session was moderated by Dr Ravi Shah from Northwestern University and Dr Christy Avery from the University of North Carolina.

Dr Yi Li from Boston University, using data from the Framingham Heart Study Offspring Cohort, found several metabolites associated with AHA's cardiovascular health score; a subset, primarily lipids and tricarboxylic acid cycle intermediates, partially mediated the relationship between the cardiovascular health score and incident heart failure. ²²

Shutong Du from Johns Hopkins University identified protein biomarkers associated with diet quality, as assessed by the Alternative Healthy Eating Index‐2010, the Alternative Mediterranean Diet, the Dietary Approaches to Stop Hypertension diet, and the Healthy Eating Index‐2015 scores, using data from ARIC Study visit 3. They identified proteins representative of a range of healthy dietary patterns and proteins that were specific to a single healthy dietary pattern. ²³

Dr Carolina Downie from the University of North Carolina presented the results of a GWAS evaluating potential modification by genetic variations in the effect of thiazide diuretics on low‐density lipoprotein cholesterol, high‐density lipoprotein cholesterol, and triglyceride concentrations. The thiazide low‐density lipoprotein cholesterol GWAS identified 1 locus which harbored several genome‐wide significant variants that modified the effect of thiazide diuretic use on low‐density lipoprotein cholesterol. ²⁴

Dr Danielle Haslam from Harvard University examined the relationship between a novel metabolomic profile reflecting artificially sweetened beverage consumption and T2D risk among US adults, using data from the Nurses' Health Study, the Nurses' Health Study II, and the Health Professionals Follow‐Up Study. The study did not identify a robust metabolomic profile of artificially sweetened beverage intake; however, the objective and replicable artificially sweetened beverage‐derived metabolomic profile was associated with higher incident T2D risk. ²⁵

Dr Adam Ware from the University of Utah and colleagues examined the number of pediatric patients undergoing genetic testing for familial hypercholesteremia and evaluated differences between genotype positive and negative probands. They found over half of the tested pediatric patients were genotype positive. Patients who were genotype‐positive were more likely to meet clinical criteria for familial hypercholesteremia, have higher total cholesterol, and low‐density lipoprotein cholesterol compared with genotype‐negative probands, and undergo more screening tests. ²⁶

Dr Nicole Armstrong from the University of Alabama at Birmingham presented results of a case–control single‐variant GWAS in patients with apparent treatment‐resistant hypertension. Gene‐based tests were stratified by race and functional impact of variants. Among Black patients only, they identified and replicated a ZFHX3 variant, previously shown to be associated with atrial fibrillation, systolic BP, hydrochlorothiazide‐induced metabolic effects, and ischemic stroke. ²⁷

Nutrition

A selection of oral abstracts on nutrition followed the Kritchevsky Memorial Lecture. These were moderated by Dr Maya Vadiveloo from the University of Rhode Island and Dr Monica Serra from the University of Texas Health San Antonio.

Dr Matti Marklund from the University of New South Wales modeled the potential benefits and risks of implementing a potassium‐enriched salt substitution campaign in India. By replacing table salt with the substitute, they estimated that hypertension‐related deaths would decrease substantially. However, deaths from hyperkalemia would increase slightly, primarily in those with chronic kidney disease. Overall, it was found that the intervention would prevent deaths in the total population and in those with chronic kidney disease. ²⁸

Dr Yi‐Yun Chen from the Albert Einstein College of Medicine, using the HCHS‐SOL (Hispanic Community Health Study/Study of Latinos), evaluated adherence to the alternate Mediterranean diet, the Healthy Eating Index‐2015, and the healthful plant‐based diet index among Hispanic/Latino individuals from 6 backgrounds, and the relationship between level of adherence and CVD risk. Adherence to healthy dietary patterns was highest in Mexican individuals and lowest in Puerto Rican individuals. Non‐US born Hispanic/Latino individuals, compared with US‐born individuals, showed higher adherence levels to healthy eating patterns. Adherence to healthy dietary patterns resulted in lower CVD risk in all groups of various Hispanic/Latino origin. ²⁹

Dr Luis Maldonado from the University of Southern California and colleagues found that in a low‐income Hispanic/Latina pregnancy cohort in Los Angeles, there were significant associations between higher intake of solid fats, refined grains, and cheese in the diet in the third trimester and presence of hypertensive disorders of pregnancy. ³⁰

Dr Yuni Choi from the University of Minnesota found that nutritionally rich, plant‐centered diets were associated with more favorable gut microbiome in individuals with heart failure. ³¹ Higher diet quality was associated with a higher abundance of Enterobacter and a lower abundance of Catenibacterium.

Novel Risk Factors

This session was moderated by Dr Nicholas Smith from the University of Washington and Dr Sachin Agarwal from Columbia University.

Based on data from >600 000 US military veterans with a median follow‐up of 5 years, Dr Andrea Schneider from University of Pennsylvania and her colleagues found that traumatic brain injury was associated with a risk of incident stroke. ³² The risk was stronger for hemorrhagic stroke compared with ischemic stroke and compared with transient ischemic attack.

Using data from the Women's Health Initiative Clinical Trials and Observational Study, Sophie Buchheit from Brown University reported a dose–response relationship between home radon exposure and elevated risk of developing stroke. Radon exposure was measured based on addresses linked to US Environmental Protection Agency‐predicted, county‐level, indoor, screening radon gas concentrations. ³³

Sarah Turecamo from the National Institutes of Health observed that rurality was associated with an increased risk of incident heart failure, which was independent of socioeconomic status and other traditional CVD risk factors in Southern Community Cohort Study participants who received Centers for Medicare and Medicaid Services. Whether rurality in this study represents the distance to health care remains to be elucidated. ³⁴

Dr Laila Al‐Shaar from the Pennsylvania State College of Medicine presented findings showing dietary sulfur amino acid intake was significantly associated with a higher risk of CVD, CVD mortality, and all‐cause mortality in men and women, even after adjustment for nondietary and dietary risk factors.

Dr Curtis Tilves from Johns Hopkins University examined the association of gut microbiota diversity and composition with trunk fat mass among a racially diverse sample of adults aged ≥20 years, using data from the Baltimore Longitudinal Study of Aging. Results indicated that beta diversity, but not alpha diversity, was associated with trunk fat mass. They further found 4 bacterial species (R. gnavus, Clostridium, Blautia, Dorea spp.) to be associated with trunk fat mass. ³⁵

Dr Leo Buckley from Harvard University and colleagues performed a proteome‐wide analysis to identify estimated glomerular filtration rate‐related pathways associated with incident heart failure, using data from the ARIC visits 3 and 5. They reported on 18 proteins associated with kidney dysfunction that were linked to an increased risk of heart failure. They further found complement and coagulation cascades and cytokine‐cytokine receptor interaction pathways to be enriched within proteins associated with incident heart failure. ³⁶

Physical Activity and Sleep

The physical activity and sleep session was moderated by Dr Sarah Camhi from the University of San Francisco and Dr Deborah Young from Kaiser Permanente, Southern California.

Eric Hyde from San Diego State University and the University of California, San Diego, compared self‐reported and objectively measured physical activity for predicting CVD events among older women in the Objective Physical Activity and Cardiovascular Health Study. They evaluated adherence to the physical activity component of AHA's Life's Simple 7 score using 2 self‐reported metrics and 2 accelerometry metrics and found that the accelerometry‐measured physical activity resulted in more accurate Life's Simple 7 scores than self‐reported physical activity. ³⁷

Dr Erin Dooley from the University of Alabama at Birmingham explored associations between multimorbidity (≥2 chronic conditions) and 24‐hour movement as measured by a wrist‐worn ActiGraph device in National Health and Nutrition Examination Survey participants. Movement decreased as the number of chronic conditions increased. Obesity, diabetes, stroke, chronic kidney disease, cancer, depression, and memory problems, specifically, were each associated with lower 24‐hour movement activity. ³⁸

Dr Angelique Brellenthin from Iowa State University compared the effect of aerobic, resistance, and combined aerobic/resistance exercise on sleep quality, duration, efficiency, and latency with the use of the Pittsburgh Sleep Quality Index. Participants were randomly assigned to 1 year of aerobic, resistance, or combined aerobic/resistance exercise or to a control group. Sleep quality scores improved across all groups, including the control group. Sleep duration increased in the resistance exercise group among those with <7 hours of sleep at baseline. In addition, the resistance exercise group showed increases in sleep efficiency and decreases in sleep latency. ³⁹

Dr Julio Fernandez‐Mendoza from Pennsylvania State University examined associations of sleep‐disordered breathing from childhood through young adulthood and carotid intima‐media thickness using data from the Penn State Child Cohort. Sleep‐disordered breathing, as measured by cumulative apnea/hypopnea index at 3 time points, was associated with greater carotid intima‐media thickness in young adulthood, but the association diminished after controlling for BMI, suggesting that obesity plays an important role in the association of sleep‐disordered breathing and carotid intima‐media thickness in young adulthood. ⁴⁰

Dr Kelsie Full, from the University of Minnesota explored associations of sleep regularity with measures of subclinical CVD using data from the MESA Sleep Study. Those with irregular sleep duration were more likely to have high coronary artery calcium, carotid plaque, and an abnormal ankle‐brachial index compared with those with regular sleep duration. Those with irregular sleep timing were >3 times as likely to have high coronary artery calcium burden compared with those with regular sleep timing. ⁴¹

Dr Lora Burke from the University of Pittsburgh and her team examined the effect of self‐monitoring plus personalized feedback or self‐monitoring alone on adherence to dietary, physical activity, and weight loss goals in participants in the Smarter Randomized Control Trial. The effect of the active intervention on adherence to the dietary goal was significant but adherence to physical activity goals was not significant. ⁴²

Jeremiah and Rose Stamler Research Award for New Investigators Finalist Presentations

The 2022 session was particularly poignant given the recent passing of Jeremiah Stamler on January 26, 2022, at 102 years of age. The session was moderated by Dr Martha Daviglus from the University of Illinois Chicago and Dr Erin Michos from Johns Hopkins University.

First, Dr Natalie Cameron from Northwestern University conducted an age‐period‐cohort analysis and found maternal age, delivery year, and maternal birth year were associated with hypertensive disorders of pregnancy rates among nulliparous individuals with singleton live births. Higher maternal age was associated with a higher risk of hypertensive disorders of pregnancy. Additionally, higher rates of hypertensive disorders of pregnancy were found in recent years (2000–2004), compared with past years (1980–1984), highlighting the need for preventive efforts. Dr Cameron was the 2022 Stamler Research Award winner. ⁴³

Next, Wendy Wang from the University of Minnesota presented evidence from real‐world data (US MarketScan data 2013–2019) on the beneficial cardiovascular effects of sodium‐glucose co‐transporter 2 inhibitors in patients with T2D. Compared with various other diabetes medications, sodium‐glucose co‐transporter 2 inhibitors use was associated with reduced rates of stroke, atrial fibrillation, myocardial infarction, and heart failure, complementing results from the large randomized controlled cardiovascular outcomes trials. ⁴⁴

Dr Hao Ma from Tulane University presented on the relationship between the timing of alcohol intake and the risk of T2D. This study found that moderate alcohol intake, when ingested with a meal, was associated with the lowest risk of incident T2D; this finding was largely driven by wine, as opposed to beer or liquor, intake. ⁴⁵ He acknowledged that individuals who drink with meals also frequently have different dietary patterns from others, which could be one of the major confounding factors unaccounted in this analysis.

Finally, Amelia Wallace from Johns Hopkins University presented on the risk of progression from prediabetes to T2D and demonstrated differences in risk based on different definitions of prediabetes. Her research found that fasting glucose, hemoglobin A1c, and BMI were the strongest predictors of progression. ⁴⁶

Notably, Dr Andrew Agbaje from the University of Eastern Finland was nominated for his work on adolescent arterial stiffness and elevated resting heart rates in young adulthood, but was unable to present during this session. ⁴⁷

Biomarkers and Risk Prediction

The session on biomarkers and risk prediction followed Dr Miguel Hernan's Richard D. Remington Methodology Lecture. This session was moderated by Dr Alanna M. Chamberlain from the Mayo Clinic and Dr Phil Gona from the University of Massachusetts Boston.

Dr Matthew Belanger from Yale University presented results from the DASH‐Sodium (Dietary Approaches to Stop Hypertension ‐ Sodium) trial which showed that consuming a Dietary Approaches to Stop Hypertension diet over 12 weeks significantly reduced biomarkers of subclinical cardiac injury and systemic inflammation, high‐sensitivity cardiac troponin I, and high‐sensitivity CRP (C‐reactive protein). ⁴⁸

Dr Yoriko Heianza from Tulane University used data from the POUNDS (Preventing Obesity Using Novel Dietary Strategies) Lost trial to examine whether weight‐loss diet‐induced changes in primary and secondary bile acids were associated with the improvements in lipid profiles. They found that primary and secondary bile acid subtype changes attributable to the implementation of a weight‐loss diet were associated with improved lipid profiles. ⁴⁹

Dr Matthew Huber from the University of Washington discussed the relationship between proteins and incident coronary heart disease in community‐dwelling older adults enrolled in the Cardiovascular Health Study. Ten proteins showed associations with incident coronary heart disease; one specific protein, macrophage metalloelastase, may have a potential causal relationship with coronary heart disease risk. ⁵⁰

Dr Junia de Brito from the University of Minnesota used Now Everybody Together for Amazing and Healthful Kids (also known as NET‐Works) data to show that high BMI in early childhood resulted in a sustained trajectory of accelerated weight gain throughout childhood. They discovered that cumulative exposure to high BMI bears a significant risk for elevated levels of inflammatory biomarkers CRP and leptin, and reduced levels of the anti‐inflammatory biomarker adiponectin. ⁵¹

Hypertension

This session was moderated by Dr Michelle Meyer from the University of North Carolina, and Dr Paul Muntner from the University of Alabama at Birmingham.

Oluwasegun Akinyelure from the University of Alabama at Birmingham showed that social determinants of health accounted for one fifth of the excess risk in uncontrolled BP among Black adults compared with White adults in the REGARDS (The Reasons for Geographic and Racial Differences in Stroke) study. Interventions to improve social determinants of health may improve BP control and reduce disparities in CVD among Black populations. ⁵²

Amanda Clarke from Eastern Virginia Medical School presented early findings from the HEALS Med‐Tech intervention, a 12‐month lifestyle program aimed at reducing BP compared with standard care. The intervention was comprised of a behavioral lifestyle intervention focused on¹ healthy eating and living spiritually, (2) medication management and social support, and (3) telehealth services to address health care access barriers. Preliminary results demonstrated a significant reduction of systolic and diastolic blood pressure as a result of the intervention compared with the control. ⁵³

Dr Ayana April‐Sanders from Albert Einstein College of Medicine reported on the prevalence and patient characteristics associated with hypertension treatment and control in the Montefiore Health System. The findings showed that rates of hypertension treatment and control in the Montefiore health system were lower than the national average; Asian and White adults had a better BP control compared with Black and Hispanic adults. ⁵⁴

Dr Kendra Sims from the University of California, San Francisco examined the association between neighborhood factors and hypertension in older adults in the Health and Retirement Study. The findings showed that recent homeownership and residing in a census tract with recent in‐migration was associated with reduced likelihood of hypertension. ⁵⁵

Dr Timothy Plante from University of Vermont examined the relationship between inflammatory cytokines and incident hypertension using REGARDS study data, which provided insight that hypertension origins may be inflammatory in nature. ⁵⁶

Finally, Dr Michelle Odden from Stanford University presented trends in hypertension diagnosis, treatment, and control among Veterans Affairs nursing home residents; there was a modest trend towards reduction in antihypertensive therapy. In addition, Black and Hispanic residents and those with chronic conditions were less likely to have BP controlled to guideline standards. ⁵⁷

COVID‐19 Updates

The session on COVID‐19 and Cardiovascular Health Updates was moderated by Dr David Goff, from the NHLBI, and Dr Shamarial Roberson, from Indelible Business Solutions Inc.

Dr Ryan Demmer from the University of Minnesota discussed several key methodological limitations that preclude causal inference between postacute sequelae of COVID‐19 and adverse cardiovascular outcomes following the resolution of acute infection, including the lack of rigorous preinfection and prepandemic phenotyping to rule out confounding by cardiovascular disease risk factors known to increase risk for both COVID‐19 and future cardiovascular events, and the lack of knowledge on underlying biological mechanisms of long‐COVID.

Dr Oluwabunmi Ogungbe from Johns Hopkins University discussed results from a systematic review and meta‐analysis examining associations between biomarkers of subclinical myocardial injury, coagulopathy, and inflammation with severe COVID‐19 and death among hospitalized patients. The study team observed a high prevalence of comorbid conditions (hypertension/T2D) in the sample and found elevated biomarkers to be significantly associated with severe COVID‐19 and death. ⁵⁸

Dr Adovich Rivera from Northwestern University discussed findings from a study that assessed the relationship of antecedent statin use with death, intubation, and ICU admission in patients admitted for COVID‐19. Compared with nonusers, antecedent statin users had a lower risk of composite adverse outcomes, but there was no significant difference in mortality between the 2 groups. Antecedent statin use was associated with a lower risk of intensive care unit admissions but not with intubation or in‐hospital mortality. ⁵⁹

Dr Luisa Alvarez from the Albert Einstein College of Medicine discussed racial/ethnic differences in the association between social determinants of health and hospitalization and mortality among patients who were positive for COVID‐19, using ambulatory care data from Bronx Montefiore Health System. Among White patients, greater use of public transportation was associated with higher odds of hospitalization. Greater household size was associated with lower odds of mortality among Hispanic patients, but increased odds of mortality among White patients. ⁶⁰

Dr Sahishnu Patel from the Medical College of Wisconsin examined prehospital patient characteristics associated with Type II non–ST‐segment–elevation myocardial infarction among hospitalized patients with COVID‐19 using data from the AHA COVID‐19 Cardiovascular Disease Quality Improvement Registry. Those who were Hispanic and used antihyperglycemic medication before admission had lower odds of Type II non–ST‐segment–elevation myocardial infarction. Meanwhile, those with chronic kidney disease, CAD, chronic heart failure, and hypertension had higher odds of Type II non–ST‐segment–elevation myocardial infarction. ⁶¹

Aging and Brain Health

The session was moderated by Dr Kelley Gabriel from the University of Alabama Birmingham and Dr Priya Palta from Columbia University.

Dr Mark Lee from the University of Minnesota and colleagues used nationally representative survey data to show that about two‐fifths of the dementia cases in the US are attributable to modifiable risk factors. The greatest effects were observed for hypertension, obesity, and physical inactivity. Among Black and Hispanic Americans, modifiable risk factors accounted for approximately one half of dementia cases. ⁶²

Dr Christopher Schaich from Wake Forest University showed that among older MESA participants, poor glycemic control, as indicated by higher visit‐to‐visit fasting glucose variability at 5 follow‐up visits, was associated with higher odds of cognitive decline. Adults at high risk of T2D during mid‐ to late‐life may be particularly affected. ⁶³

Chelsea Liu from Harvard University presented an analysis of the role of mid‐life hypertension, diabetes, BMI, and smoking as potential vascular mediators in the association between education and dementia in the ARIC study. They found that half of the associations were mediated through these vascular risks. The association was weaker among high‐risk patients with incident stroke. ⁶⁴

Dr Xiaoran Liu from the Rush University presented results using Chicago Health and Aging Project (1993–2012) data indicating that Black individuals had a higher dietary consumption of animal products, sugar‐sweetened beverages, and whole grains compared with White individuals. He also reported an association between higher healthful plant‐based diet index scores and a slower rate of global cognitive decline in Black individuals, but not in White individuals. These results suggest that dietary patterns differ by race and provide information for the development of tailored dietary recommendations for cognitive decline prevention. ⁶⁵

Dr Monik Jimenez from Harvard University evaluated the heterogeneity in stroke symptoms among Hispanic/Latino participants from the HCHS‐SOL in midlife. She and colleagues found the prevalence of ≥1 stroke symptom was higher among those with mixed heritage. The findings demonstrate the high burden of stroke symptoms in relatively young individuals and differences across heritage groups, indicating the need for targeted stroke recognition education. ⁶⁶

Frances Wang from Johns Hopkins University presented online‐panel survey results showing a general trend in older adults considering the preventive benefits of medications for stroke and myocardial infarction (eg, statins, aspirin) over their side‐effects. This suggests that older adults tend to prioritize the benefits of preventive therapies and that integrating individualized patient preferences is an essential step in developing precision treatment strategies. ⁶⁷

Preventive Cardiology

After the Kannel Memorial Lecture, oral abstracts on preventive cardiology were moderated by Dr Sadiya Khan from Northwestern University and Dr Ambarish Pandey from the University of Texas Southwestern Medical Center.

Dr Alexander Berry from Geisinger explored familial hypercholesterolemia subtype data from the UK Biobank. They found all 4 subtypes of familial hypercholesterolemia resulted in an increased CVD risk if left untreated. ⁶⁸

Dr Susan Hennessy from the University of California, San Francisco, CA, found that the primary missed opportunities related to the control of hypertension in premenopausal women were lack of health care access, uncontrolled hypertension, and lack of hypertension awareness, using National Health and Nutrition Examination Survey data. Non‐Hispanic Black and Hispanic women were more likely to have a lack of health care access compared with the average US population. ⁶⁹

Toluwa Omole from the University of Pittsburgh conducted a retrospective analysis of patients with incident, nonvalvular atrial fibrillation with 2015 to 2020 data from a large, regional health center, and showed that among people with atrial fibrillation, those living in the areas with the highest levels of deprivation were less likely to receive any anticoagulation and were less likely to receive a direct oral anticoagulant than those living in areas with the lowest levels of deprivation. ⁷⁰

Dr Alexander Heilman from the University of Colorado used Veterans Affairs Health Care System data to examine initiation of primary prevention after diabetes diagnosis and found that rates of statin initiation and lipid control were suboptimal in the first 5 years after diabetes diagnosis in the Veterans Affairs Health Care System. ⁷¹

Dr Michael Hammond from Northwestern University concluded the session with a study using data from the National Health and Nutrition Examination Survey; they found statin use is low in individuals with borderline or intermediate CVD risk who have risk‐enhancing factors that may qualify them for statin therapy. ⁷²

Pregnancy/Maternal and Childhood

Dr Noel Mueller from Johns Hopkins University and Dr Sarah de Ferranti from Boston Children's Hospital moderated the session.

Dr Nour Makarem from Columbia University used data from the Nulliparous Pregnancy Outcomes Study to show that first‐time pregnant women with the closest adherence to the alternative Mediterranean diet pattern had significantly lower odds of developing any adverse pregnancy outcomes, including preeclampsia/eclampsia and gestational diabetes. Higher intakes of vegetables, fruits, legumes, and fish and a lower intake of red meat were associated with lower odds of adverse pregnancy outcomes. ⁷³

Dr Jewel Scott from University of Pittsburgh reported on socioeconomic and pregnancy‐related differences in BP phenotypes in the decade following pregnancy – higher BMI, Black race, having a baby small‐for‐gestational age, and hypertension disorder in pregnancy were associated with sustained hypertension later in life (up to 10 years after delivery of the index pregnancy). ⁷⁴

Dr Rebecca Jones from Emory University reported on diet behaviors in early life and childhood using data from the Early Childhood Longitudinal Study Birth cohort. Findings showed tracking of BMI Z‐score in US children and emphasized the importance of obesity intervention within the first 2 years of life.

Sudeep Neupane, on behalf of Dr Liang Wang from Baylor University, presented on a study using data from the National Institute of Child Health and Human Development SECCYD (Study of Early Child Care and Youth Development) to show that poverty status, in addition to non‐White race and higher birthweight, was associated with obesity in US children. Findings highlight the need for system‐level interventions to address childhood obesity. ⁷⁵

Rachel Kohler from West Virginia University presented on follow‐up care insufficiencies from a school‐based cross‐sectional cholesterol screening program and reported on the insufficiency of follow‐up care for kids with probable familial hypercholesterolemia. ⁷⁶

National Heart, Lung, and Blood Institute Cardiovascular Epidemiology, Biostatistics, and Prevention Trainee Session

The 2 NHLBI hybrid trainee sessions included work from 15 trainees from 9 institutions, ⁷⁷ , ⁷⁸ , ⁷⁹ , ⁸⁰ featured several National Institutes of Health‐funded cohort studies, and covered a wide range of topics. The first session was moderated by Dr Duke Appiah from Texas Tech University and Dr Paul Mutner from the University of Alabama at Birmingham. The second session was moderated by Dr Elizabeth Selvin from Johns Hopkins University and Dr Nicole Redmond from the NHLBI.

Major themes included diet and food security, psychosocial and emotional risk factors, physical activity, and biomarkers. Three studies showed that higher physical activity was associated with improved CVD and CVD risk factors, including lower risk for ischemic stroke, ⁸¹ lower markers of inflammation, ⁸² improved mental health, and improved cardiometabolic health among survivors of childhood maltreatment. ⁸³ Two studies using cohorts of adolescents and young adults showed that unhealthy eating behaviors were associated with both experiences of interpersonal racism ⁸⁴ and parent perception of their children as overweight. ⁸⁵ A study using data from the coronary artery risk development in young adults (CARDIA) cohort showed that food insecurity was highest among women and Black participants, and that women with food insecurity were less likely to have BP controlled. ⁸⁶ Another study in the CARDIA study cohort found that modifiable risk factors may explain the increased risk of dementia in older women compared with older men. ⁸⁷ Two studies from the ARIC study cohort showed that decreases in diet quality were associated with a higher risk of chronic kidney disease progression, but the use of dietary supplements had no effect on the risk of chronic kidney disease progression. ⁸⁸

EARLY CAREER COMMITTEE EVENTS

Rapid Fire Oral Abstracts

Dr Bethany Gibbs from the University of Pittsburgh moderated the first Early Career Committee event and provided an insightful and heartfelt keynote to the audience, describing her early career experience, underscoring the importance of excellent mentorship to help advance skills and achieve success as an independent research investigator.

Four finalists (Table 1) competed in the Rapid‐Fire Oral Abstract Competition composed of a 3‐minute presentation and 7 minutes of question‐and‐answer interaction with the judges: Immediate‐past AHA president (2021 to 2022) Dr Donald Lloyd‐Jones, Dr Priya Palta, and Dr Elizabeth Selvin. Tung Nguyen won first place for research on work in gene deletion (Nup93) on the impairment of endothelial structure. The year's runner‐up was Brittany Pope from University of South Carolina, who described the role of estrogen in regulating social stress responses in murine models.

Table 1.

Rapid‐Fire Oral Abstract Competition

Finalists	Presentation Title
Tung Nguyen, BS (First Place) Doctoral Student University of Illinois Chicago	Nup93 Deletion Impairs Endothelial Barrier Integrity and Cell Migration Through Induced Cellular Senescence
Brittany (Pope) Pate, BS (Second Place) Doctoral Student University of South Carolina	Estrogen‐Specific Regulation of Social Stress Susceptibility in Female Rats
Jacob Adams, BS Master's Student University of Alabama at Birmingham	Effects of High‐Intensity Interval Training Versus Moderate‐ Intensity Training on Cardiometabolic Health Markers in Individuals With Spinal Cord Injury: A Pilot Study
Patricia Pagan Lassalle, MS Doctoral Student University of North Carolina at Chapel Hill	Do 24‐Hour Beneficial Behaviors Associated With COVID‐19 Prevalence Differ by Cancer History?
Samantha Vega, MPH Doctoral Student University of Illinois Chicago	Using geographic information science to Investigate COVID‐19 Attributed Gentrification in Chicago

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COUNCIL NETWORKING LUNCHEONS

Two sessions, hosted by the EPI and Lifestyle Councils, featured presentations, and panel discussions from both early‐career and more senior investigators (Table 2).

Table 2.

Discussants for the Lifestyle and EPI Council Luncheons

Lifestyle Council: “Thriving as a Researcher in Virtual and Hybrid Environments”
Panelists	Dr Mercedes Carnethon	Mary Harris Thompson Professor and Vice Chair of Preventive Medicine at Northwestern University
	Dr William E. Kraus	Richard and Pat Johnson University Distinguished Professor, Professor of Medicine at Duke University
	Dr Leanna Ross	Postdoctoral Research Fellow at Duke University
	Dr Timothy Plante	Assistant Professor of Medicine, University of Vermont
EPI Council: “EPI Goes Green for Heart Health!”
Moderator	Dr Sadiya Khan	Assistant Professor of Medicine at Northwestern University and Chair of EPI Council Early Career Committee
Panelists	Dr Holly Gooding	Associate Professor of Pediatrics at Emory University
	Dr Tiffany Powell‐Wiley	Stadtman Investigator and Chief of the Social Determinants of Obesity and Cardiovascular Risk Laboratory at NHLBI and Adjunct Investigator at NIMHD
	Dr David Goff Jr	Director of the Division of Cardiovascular Sciences at NHLBI

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EPI indicates Council on Epidemiology and Prevention; and NHLBI, National Heart, Lung, and Blood Institute.

During the Lifestyle Council luncheon panel discussion themed “Thriving as a Researcher in Virtual and Hybrid Environments,” Dr Leanna Ross shared a practical virtual adaptation example to address study participants' attrition and improve recruitment and retention. Dr Mercedes Carnethon highlighted challenges faced by subgroups of participants, including the unprecedented need for more educational support faced by many studies. Dr William Kraus shed light on ethical requirements to conduct research remotely and indicated that of 3 models of clinical study participation: (1) onsite, (2) hybrid, and (3) home‐based. In his experience, the hybrid model was the least desirable as participants preferred either absolute in‐person/on‐site interactions or home‐based visits over hybrid. Dr Timothy Plante and Dr Carnethon discussed COVID‐19–related isolation and work‐life balance. They emphasized the importance of healthy breaks and downtime to maintain energy and prevent burnout. Drs. Ross and Kraus stressed the importance of task prioritizations, including allocating productive morning time to self and avoiding early or after‐hours meetings. Virtual T32 fellow seminars and empowering the postdoctoral association committees inside academic centers were suggested as methods to overcome networking barriers.

At the EPI Council Luncheon themed “EPI Goes Green for Heart Health,” Dr Holly Gooding highlighted the successful work described in her recent paper on preventive cardiovascular interventions in an adolescent health clinic. Dr Tiffany Powell‐Wiley described her experiences and findings on environmental factors (eg, built environment, neighborhood resources, and impoverishment) that impact obesity and related disorders and her work to develop policy and community‐level interventions for promoting healthy behavior change. Dr David Goff shared observations from his unique role overseeing the allocation of funds by NHLBI and how the paradigm has changed under the current administration to support the investigation of environmental and climate‐driven influences on cardiovascular health.

Networking Roundtables

On Wednesday and Friday, attendees had the opportunity to discuss several topics with colleagues at networking roundtables (Table 3).

Table 3.

Networking Roundtables

Topic	Moderators
Wednesday, March 2, 2022
Meet the Keynote Speakers	Sanjay Rajagopalan, MD, FACC, FAHA Professor of Medicine and Director of the Cardiovascular Research Institute at Case Western Reserve University Christopher D. Gardner, PhD, FAHA Professor of Medicine and Director of Nutrition Studies at Stanford University
Sleep	Marie‐Pierre St‐Onge, PhD, FAHA, CCSH Associate Professor of Nutritional Medicine and Director of Sleep Center of Excellence at Columbia University
How to Publish Meaningfully	Ruth‐Alma Turkson‐Ocran, PhD, MPH, APRN Clinical Investigator and Instructor of Medicine at Beth Israel Deaconess Medical Center & Harvard Medical School Joshua Joseph, MD, MPH, FAHA Assistant Professor of Endocrinology, Diabetes and Metabolism at The Ohio State University Wexner Medical Center
Physical Activity in Pregnancy	Kara Whitaker, PhD, MPH, FAHA Assistant Professor of Health Promotion at The University of Iowa Bethany Barone Gibbs, PhD, FAHA Associate Professor of Epidemiology at The University of Pittsburgh
Health Literacy	Jared Magnani, MD, MSc, FAHA Associate Professor of Medicine at The University of Pittsburgh La Princess C. Brewer, MD, MPH Assistant Professor of Medicine at The Mayo Clinic
Genetic Epidemiology	Kari North, PhD, FAHA Professor of Epidemiology at University of North Carolina
Friday, March 4, 2022
Meet the Remington Lecturer	Miguel Hernán, MD, DrPH Professor of Biostatistics and Epidemiology at Harvard T.H. Chan School of Public Health
Meet the Kannel Lecturer	Dan M. Roden, MD, FAHA Professor of Medicine and Pharmacology at Vanderbilt University Medical Center
Navigating Microaggressions and Implicit Bias	Monik Jimenez, ScD, FAHA Assistant Professor of Medicine & Associate Epidemiologist at Harvard Medical School & Brigham and Women's Hospital Cheryl Anderson, PhD, MPH, FAHA Professor and Dean of the University of California San Diego Herbert Wertheim School of Public Health and Human Longevity Science
Behavioral Interventions	Anne Thorndike, MD, MPH, FAHA Associate Professor of Medicine at Harvard Medical School & Massachusetts General Hospital Mark Periera, PhD, MPH Professor of Epidemiology at University of Minnesota
Cardiac Biomarkers	Chiadi Ndumele, MD, PhD, MHS, FAHA Assistant Professor of Medicine at Johns Hopkins University
Social Determinants of Health Across the Lifecourse	Tiffany M. Powell‐Wiley MD, MPH, FAHA Stadtman Investigator and chief of the Social Determinants of Obesity and Cardiovascular Risk Laboratory at the National Heart, Lung, and Blood Institute

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Council Awards

Several council awards were presented, including the Council on Epidemiology and Prevention Conference Awards (Table 4), and the Council on Lifestyle and Cardiometabolic Health Conference Awards (Table 5).

Table 4.

Council on Epidemiology and Prevention Conference Awards

Awards	Presenter and Title
Roger R. Williams Award for Genetic Epidemiology and the Prevention and Treatment of Atherosclerosis	Leo F Buckley, PharmD Proteins Linking Chronic Kidney Disease to Incident Heart Failure in Adults With Chronic Kidney Disease: The Atherosclerosis Risk in Communities Study
Trudy Bush Fellowships for Cardiovascular Disease Research in Women's Health	Nour Makarem, PhD A Mediterranean Diet Pattern Is Associated With Lower Risk of Adverse Pregnancy Outcomes in US Women: Results from the NuMoM2b Cohort Mary Rooney, PhD, MPH Performance of Glycated Albumin as a Marker of Hyperglycemia During Pregnancy: Results from the National Health and Nutrition Examination 1999–2004 Bhavya Varma, MD Associations Between Endogenous Sex Hormone Levels and Adipokine Levels in the Multi‐ethnic Study of Atherosclerosis (MESA)
Epidemiology and Prevention Mentoring Award	Tiffany M. Powell‐Wiley, MD, MPH, FAHA
Sandra A. Daugherty Award for Excellence in Cardiovascular Disease or Hypertension Epidemiology and Prevention	Timothy B. Plante, MD, MHS (Winner) Inflammatory Cytokines and Incident Hypertension in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study Kelsie M. Full, PhD, MPH (Finalist) Sleep Regularity and Subclinical Markers of Cardiovascular Disease: The Multi Ethnic Study Of Atherosclerosis (MESA) Jessica Reese, PhD (Finalist) Dyslipidemia and the Incidence of Subclinical and Clinical Cardiovascular Disease in Adolescents and Young Adults: The Strong Heart Family Study (SHFS) Yacob Tedla, PhD (Finalist) Association of Elevated High‐Sensitive Cardiac Troponin T and Low Ankle‐Brachial Index With Incident Cardiovascular Events. The Multi‐Ethnic Study of Atherosclerosis and the Cardiovascular Health Study
Jeremiah and Rose Stamler Research Award for New Investigators	Natalie A. Cameron, MD (Winner) Trends in Hypertensive Disorders of Pregnancy Among Nulliparous Individuals With Singleton Live Births in the United States: An Age‐Period‐Cohort Analysis Between 1995–2019 Andrew Agbaje, MD, MPH (Finalist) Adolescent Arterial Stiffness Precedes Elevated Resting Heart Rate in Young Adulthood: A 7‐year Temporal Longitudinal Analysis Using Cross‐Lagged Structural Equation Model Hao Ma, MD, PhD (Finalist) Moderate Alcohol Drinking With Meals Is Related to Lower Incidence of Type 2 Diabetes Amelia S. Wallace, MS (Finalist) Remission of Prediabetes in Middle‐Age and Risk of Long‐Term Complications Wendy Wang, MPH (Finalist) Real‐World Evidence Demonstrating the Association of SGLT2 Inhibitors With Reduced Cardiovascular Disease in Patients With Type 2 Diabetes
Epidemiology and Prevention Early Career Travel Grant	Lily D. Yan, MD, MSc Pablo Martinez‐Amezcua, MD, PhD, MHS Oluwabunmi Ogungbe, MPH Haley W. Parker, MS, RD
Epidemiology and Prevention Underrepresented Racial and Ethnic Groups Travel Grant	Hamdi S. Adam, MPH Jonathan J. Ruiz‐Ramie, PhD, MS Lola R. Ortiz‐Whittingham Janiya C. Sutton

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SGLT2 indicates sodium‐glucose co‐transporter 2.

Table 5.

Council on Lifestyle and Cardiometabolic Health Conference Awards

Awards	Presenter and Title
Award for Excellence in Research Addressing Cardiovascular Health Equity	Luis Enrique Maldonado, PhD, MPH Maternal Dietary Patterns During Late Pregnancy Are Linked to Hypertensive Disorders of Pregnancy Among a Low‐Income Predominantly Hispanic/Latina Pregnancy Cohort in Los Angeles
Scott Grundy Award for Excellence in Metabolism Research	Michael P. Bancks, PhD, MPH Differential Effect of An Intensive Lifestyle Intervention on Risk for Cardiovascular Events According to Baseline Level of Glycated Hemoglobin Kei Hang Katie Chan, PhD, MPH Identification of Genetic Signals For “Diabesity” ‐‐‐ Type 2 Diabetes and Obesity ‐‐ Among African American and European American Participants in Four Cohorts of the TOPMed Consortium Christopher L. Schaich, PhD, MS Higher Visit‐to‐Visit Variability in Fasting Glucose and Hemoglobin A1c Is Associated With Decline in Global Cognitive Performance: The Multi‐Ethnic Study of Atherosclerosis (MESA)
Steven N. Blair Award for Excellence in Physical Activity Research	Erin Dooley, MS, PhD Multimorbidity Is Associated With Lower 24‐Hour Total Movement Activity Among US Adults
Mark Bieber Award	Alex Chang, MD, MS Telehealth Versus Self‐Directed Lifestyle Intervention to Promote Healthy Blood Pressure: A Randomized Controlled Trial
Early Investigator Travel Award	Yi‐Yun Chen, MD, MSc Serena Jingchuan Guo, MD, PhD Xiaoran Liu, PhD, MSc, FAHA Mercedes Sotos‐Prieto, PhD

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CONCLUSIONS

The 2022 AHA EPI|Lifestyle Scientific Sessions, held in Chicago, IL, brought back the exciting and empowering atmosphere of an in‐person conference for investigators from all over the world with an interest in sharing the latest evidence and insights on the prevention and treatment of CVDs. Last year's focus on emerging cardiovascular science on food sustainability and environmental health will likely become even more pressing in years to come. The 2023 AHA EPI|Lifestyle Scientific Sessions which featured several presentations on scientific advances and innovations to optimize individual and population cardiovsacular health was in held in Boston, MA, in March 2023.

Sources of Funding

A.S.W., O.T., and F.W. are supported by National Institutes of Health/National Heart, Lung, and Blood Institute grant T32HL007024. K.N.K. is supported by Health Resources and Services Administration grant T32HP32715. D.A.D. is supported by National Institutes of Health/National Institute on Aging grant 2RF1AG041200‐06 and American Heart Association grant 20SFRN35360180. E.T.H. is supported by National Institutes of Health/National Heart, Lung, and Blood Institute grant T32HL07989114. M.Z. is supported by American Heart Association award number 827990. R.A.T.O. is supported by the American Heart Association's Health Equity Research Network on the Prevention of Hypertension grant 878488 and the National Institutes of Health's National Heart, Lung, and Blood Institute grant 3RO1HL158622‐01S1. O.O. is supported by the American Heart Association's Health Equity Research Network on the Prevention of Hypertension grant 882415 and the Strategically Focused Research Network Center Science of Diversity in Clinical Trilas grant 953550. The views expressed in this publication are those of the authors and do not necessarily reflect the official policy of the American Heart Association, the National Institutes of Health, the Department of Defense, the Department of the Army, the US Army Medical Department, or the US Government.

Disclosures

Ruth‐Alma Turkson‐Ocran serves on the JAHA Editorial Board.

For Sources of Funding and Disclosures, see page 14.

All abstracts published in conjunction with the American Heart Association's EPI|Lifestyle 2022 Scientific Sessions can be found online here: https://www.ahajournals.org/toc/circ/145/Suppl_1

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28. Marklund M, Gupta R, Tullu FT, Neal B, Wu JH. Abstract 019: estimated benefits and risks of lowering sodium through potassium‐enriched salt substitution in India: a modeling study. Circulation. 2022;145:A019. doi: 10.1161/circ.145.suppl_1.019 [DOI] [Google Scholar]
29. Chen Y‐Y, Chen G‐C, Abittan N, Xing J, Mossavar‐Rahmani Y, Sotres‐Alvarez D, Mattei J, Daviglus M, Isasi CR, Hu FB, et al. Abstract 020: healthy dietary patterns and risk of cardiovascular disease in US Hispanics/Latinos: the Hispanic community health study/study of Latinos (HCHS/SOL). Circulation. 2022;145:A020. doi: 10.1161/circ.145.suppl_1.020 [DOI] [PMC free article] [PubMed] [Google Scholar]
30. Maldonado LE, Toledo‐Corral CM, Dunton G, Farzan S, Breton CV, Bastain TM. Abstract 021: maternal dietary patterns during late pregnancy are linked to hypertensive disorders of pregnancy among a low‐income predominantly Hispanic/Latina pregnancy cohort in Los Angeles. Circulation. 2022;145:A021. doi: 10.1161/circ.145.suppl_1.021 [DOI] [Google Scholar]
31. Choi Y, Yuzefpolskaya M, Bohn B, Molinsky R, Pinsino A, Braghieri L, Johnson A, Duprez D, Colombo PC, Jacobs DR, et al. Abstract 022: association of nutritionally‐Rich Plant‐centered diets with gut microbial diversity and composition Columbia heart failure‐microbiome study. Circulation. 2022;145:A022. doi: 10.1161/circ.145.suppl_1.022 [DOI] [Google Scholar]
32. Schneider AL, Peltz C, Li Y, Bahorik A, Gardner R, Boscardin WJ, Yaffe K. Abstract 024: traumatic brain injury and long‐term risk of stroke among U.S. military veterans. Circulation. 2022;145:A024. doi: 10.1161/circ.145.suppl_1.024 [DOI] [PMC free article] [PubMed] [Google Scholar]
33. Buchheit SF, Collins JM, Anthony K, S‐aM L, Stewart J, Gondalia R, Manson JE, Reiner AP, Schwartz G, Vitolins M, et al. Abstract 025: radon exposure and incident stroke risk in the Women's Health Initiative. Circulation. 2022;145:A025. doi: 10.1161/circ.145.suppl_1.025 [DOI] [PMC free article] [PubMed] [Google Scholar]
34. Turecamo S, Xu M, Joo J, Dixon D, Gupta DK, Lipworth L, Roger VL. Abstract 026: rurality and incident heart failure risk in the southern community cohort study. Circulation. 2022;145:A026. doi: 10.1161/circ.145.suppl_1.026 [DOI] [Google Scholar]
35. Tilves C, Tanaka T, Differding MK, Spira AP, Ferrucci L, Mueller NT. Abstract 028: microbiota composition and diversity is associated with trunk fat: findings from Baltimore longitudinal study of aging. Circulation. 2022;145:A028. doi: 10.1161/circ.145.suppl_1.028 [DOI] [Google Scholar]
36. Buckley LF, Dorbala P, Grams M, Coresh J, Matsushita K, Claggett B, Demmer R, Ballantyne CM, Hoogeveen RC, Yu B, et al. Abstract 029: proteins linking chronic kidney disease to incident heart failure in adults with chronic kidney disease: the atherosclerosis risk in communities study. Circulation. 2022;145:A029. doi: 10.1161/circ.145.suppl_1.029 [DOI] [Google Scholar]
37. Hyde ET, Nguyen S, Lamonte MJ, Tinker L, Lacroix AZ, Bellettiere J. Abstract 036: influence of physical activity measurement on the association between Life'S simple 7 and cardiovascular disease in older women. Circulation. 2022;145:A036. doi: 10.1161/circ.145.suppl_1.036 [DOI] [Google Scholar]
38. Dooley EE, Chen L, Palta P, Martinez‐Amezcua P, Hornikel B, Muntner P, Lewis CE, Gabriel KP. Abstract 037: multimorbidity is associated with lower 24‐hour total movement activity among US adults. Circulation. 2022;145:A037. doi: 10.1161/circ.145.suppl_1.037 [DOI] [Google Scholar]
39. Brellenthin AG, Lee D‐c. Abstract 038: comparative effects of aerobic, resistance, and combined exercise on sleep. Circulation. 2022;145:A038. doi: 10.1161/circ.145.suppl_1.038 [DOI] [Google Scholar]
40. Fernandez‐Mendoza J, Gao Z, Vachhani B, Brandt K, Shah K, Liao J, He F, Calhoun S, Vgontzas AN, Liao D, et al. Abstract 039: association of a cumulative exposure to sleep disordered breathing from childhood through young adulthood with carotid intima‐media thickness. Circulation. 2022;145:A039. doi: 10.1161/circ.145.suppl_1.039 [DOI] [Google Scholar]
41. Full KM, Huang T, Shah N, Allison MA, Michos ED, Duprez D, Redline S, Lutsey PL. Abstract 040: sleep regularity and subclinical markers of cardiovascular disease: the multi ethnic study of atherosclerosis (MESA). Circulation. 2022;145:A040. doi: 10.1161/circ.145.suppl_1.040 [DOI] [PMC free article] [PubMed] [Google Scholar]
42. Burke LE, Bizhanova Z, Conroy MB, Parmanto B, Kariuki JK, Cheng J, Beatrice B, India L, Wang Y, Pulantara IW, et al. Abstract 041: effect of personalized feedback messages on adherence to the dietary, physical activity and weight loss goals‐ the smarter RCT. Circulation. 2022;145:A041. doi: 10.1161/circ.145.suppl_1.041 [DOI] [Google Scholar]
43. Cameron NA, Petito L, Shah N, Perak AM, Catov JM, Bello NA, Capewell S, Oflaherty ME, Lloyd‐jones DM, Greenland P, et al. Abstract 042: trends in hypertensive disorders of pregnancy among nulliparous individuals with singleton live births in the United States: an age‐period‐cohort analysis between 1995–2019. Circulation. 2022;145:A042. doi: 10.1161/circ.145.suppl_1.042 [DOI] [Google Scholar]
44. Wang W, Chen LY, Walker R, Chow L, Norby FL, Alonso A, Pankow JS, Lutsey PL. Abstract 043: real‐world evidence demonstrating the association of SGLT2 inhibitors with reduced cardiovascular disease in patients with type 2 diabetes. Circulation. 2022;145:A043. doi: 10.1161/circ.145.suppl_1.043 [DOI] [PMC free article] [PubMed] [Google Scholar]
45. Ma H, Wang X, Li X, Heianza Y, Qi L. Abstract 044: moderate alcohol drinking with meals is related to lower incidence of type 2 diabetes. Circulation. 2022;145:A044. doi: 10.1161/circ.145.suppl_1.044 [DOI] [PMC free article] [PubMed] [Google Scholar]
46. Wallace AS, Rooney MR, Echouffo Tcheugui J, Grams M, Selvin E. Abstract 046: remission of prediabetes in middle‐age and risk of long‐term complications. Circulation. 2022;145:A046. doi: 10.1161/circ.145.suppl_1.046 [DOI] [Google Scholar]
47. Agbaje AO, Barker AR, Tuomainen T‐P. Abstract 045: adolescent arterial stiffness precedes elevated resting heart rate in young adulthood: a 7‐year temporal longitudinal analysis using cross‐lagged structural equation model. Circulation. 2022;145:A045. doi: 10.1161/circ.145.suppl_1.045 [DOI] [Google Scholar]
48. Belanger MJ, Kovell LC, Turkson‐Ocran R‐A, Mukamal KJ, Liu X, Appel LJ, Miller ER, Sacks FM, Christenson RH, Rebuck H, et al. Abstract 047: effects of the Dash diet on change in high‐sensitivity cardiac troponin I over time: results from the Dash‐sodium trial. Circulation. 2022;145:A047. doi: 10.1161/circ.145.suppl_1.047 [DOI] [PMC free article] [PubMed] [Google Scholar]
49. Heianza Y, Xue Q, Rood J, Clish C, Bray G, Sacks F, Qi L. Abstract 048: changes in bile acid metabolism, circulating microRNA‐34a, and improvements in lipid profiles in response to weight‐loss diets: the pounds lost trial. Circulation. 2022;145:A048. doi: 10.1161/circ.145.suppl_1.048 [DOI] [Google Scholar]
50. Huber M, Bis J, Brody J, Sitlani C, Austin T, Katz D, Psaty B, Floyd JS. Abstract 050: plasma proteomics and incident coronary heart disease: the cardiovascular health study. Circulation. 2022;145:A050. doi: 10.1161/circ.145.suppl_1.050 [DOI] [Google Scholar]
51. de Brito JN, Pereira MA, Kelly AS, Erickson DJ, Sherwood NE, Mason SM, Loth KA, French S, Kunin‐Batson A. Abstract 051: association between body mass index trajectories from early to middle childhood and biomarkers of cardiometabolic risk among children living in low‐income and racially/ethnically diverse households. Circulation. 2022;145:A051. doi: 10.1161/circ.145.suppl_1.051 [DOI] [Google Scholar]
52. Akinyelure OP, Jaeger BC, Oparil S, Carson AP, Safford M, Howard G, Muntner P, Hardy ST. Abstract 052: social determinants of health and uncontrolled blood pressure in a National Cohort of Black and White US adults. Circulation. 2022;145:A052. doi: 10.1161/circ.145.suppl_1.052 [DOI] [PMC free article] [PubMed] [Google Scholar]
53. Clarke AW, El Moudden I, Newby OM, Wood L, Dodani S. Abstract 053: heals med‐tech: a telehealth based behavioral lifestyle hypertension control program for high‐risk African Americans presenting at primary care clinics. Circulation. 2022;145:A053. doi: 10.1161/circ.145.suppl_1.053 [DOI] [Google Scholar]
54. April‐Sanders AK, Golestaneh L, Zhang L, Swett K, Meissner P, Bellin EY, Rodriguez C. Abstract 054: hypertension treatment and control in a New York city healthcare system. Circulation. 2022;145:A054. doi: 10.1161/circ.145.suppl_1.054 [DOI] [PMC free article] [PubMed] [Google Scholar]
55. Sims KD, Hystad PW, Batty GD, Smit E, McGregor JC, Odden MC. Abstract 055: neighborhood‐wide association study of hypertension in the health and retirement study. Circulation. 2022;145:A055. doi: 10.1161/circ.145.suppl_1.055 [DOI] [Google Scholar]
56. Plante TB, Juraschek SP, Howard G, Howard VJ, Tracy RP, Judd SE, Kamin Mukaz D, Zakai NA, Long DL, Cushman M. Abstract 056: inflammatory cytokines and incident hypertension in the REasons for geographic and racial differences in stroke (REGARDS) study. Circulation. 2022;145:A056. doi: 10.1161/circ.145.suppl_1.056 [DOI] [Google Scholar]
57. Odden MC, Li Y, Graham L, Steinman M, Lee S, Marcum Z, Liu C, Jing B, Fung K, Peralta CA. Abstract 057: trends in blood pressure diagnosis, treatment, and control among nursing home residents, 2007–2018. Circulation. 2022;145:A057. doi: 10.1161/circ.145.suppl_1.057 [DOI] [PMC free article] [PubMed] [Google Scholar]
58. Ogungbe O, Kumbe B, Fadodun OTL, Meyer D, Asala A, Davidson P, Dennison Himmelfarb C, Post W, Commodore‐mensah Y. Abstract 058: subclinical myocardial injury, coagulopathy, and inflammation in Covid‐19: a meta‐analysis. Circulation. 2022;145:A058. doi: 10.1161/circ.145.suppl_1.058 [DOI] [PMC free article] [PubMed] [Google Scholar]
59. Rivera A, Al‐Heeti O, Petito L, Williams JL, Feinstein MJ, Taiwo B, Achenbach C. Abstract 060: association of antecedent statin use with outcomes of people with Covid‐19 admitted at northwestern medicine health system. Circulation. 2022;145:A060. doi: 10.1161/circ.145.suppl_1.060 [DOI] [Google Scholar]
60. Alvarez L, April‐Sanders AK, Lee UJ, Golestaneh L, Bellin E, Rodriguez C. Abstract 061: social determinants of health and ambulatory outcomes among Covid‐19 positive patients: differences by race/ethnicity. Circulation. 2022;145:A061. doi: 10.1161/circ.145.suppl_1.061 [DOI] [Google Scholar]
61. Patel S, Visotcky A, Devine A, Kode V, Kotlo S, Aljadah M, Sparapani R, Kulinski JP. Abstract 059: COVID‐19 and type II NSTEMI: a comprehensive overview. Circulation. 2022;145:A059. doi: 10.1161/circ.145.suppl_1.059 [DOI] [Google Scholar]
62. Lee M, Whitsel EA, Avery CL, Hughes TM, Griswold M, Sedaghat S, Gottesman RF, Mosley T, Heiss GM, Lutsey PL. Abstract 062: racial and ethnic differences in the population burden of dementia attributable to modifiable risk factors in the United States. Circulation. 2022;145:A062. doi: 10.1161/circ.145.suppl_1.062 [DOI] [Google Scholar]
63. Schaich CL, Bancks M, Hayden K, Ding J, Rapp S, Bertoni AG, Fitzpatrick AL, Heckbert SR, Hughes TM, Mongraw‐chaffin M. Abstract 063: higher visit‐to‐visit variability in fasting glucose and HbA1c is associated with decline in global cognitive performance: the multi‐ethnic study of atherosclerosis (MESA). Circulation. 2022;145:A063. doi: 10.1161/circ.145.suppl_1.063 [DOI] [Google Scholar]
64. Liu C, Ma Y, Hofman A, Waziry R, Koton S, Pike JR, Windham BG, Power MC, Sharrett AR, Gottesman RF. Abstract 065: educational attainment and dementia risk: mediation by vascular risk factors at mid‐life in the atherosclerosis risk in communities (ARIC) study. Circulation. 2022;145:A065. doi: 10.1161/circ.145.suppl_1.065 [DOI] [Google Scholar]
65. Liu X, Dhana K, Barnes L, Tangney C, Aggarwal P, Agarwal N, Holland T, Rajan K. Abstract 066: a healthy plant‐based diet was associated with slower cognitive decline in African Americans: a biracial community‐based cohort of older adults. Circulation. 2022;145:A066. doi: 10.1161/circ.145.suppl_1.066 [DOI] [PMC free article] [PubMed] [Google Scholar]
66. Jimenez MC, Lopez J, Castaneda SF, Daviglus ML, Kaplan R, Lopez L, perreira k, Rodriguez F, Wassertheil‐smoller SW, Sotres‐Alvarez D, et al. Abstract 064: prevalence of stroke symptoms among Hispanic/Latino adults in the Hispanic community health study/study of Latinos (HCHS/SOL). Circulation. 2022;145:A064. doi: 10.1161/circ.145.suppl_1.064 [DOI] [Google Scholar]
67. Wang FM, Yebyo HG, Boyd C, Puhan MA, Matsushita K, Blaha MJ, Schoenborn N. Abstract 067: outcome preferences related to cardiovascular preventive therapies in older adults: an online survey. Circulation. 2022;145:A067. doi: 10.1161/circ.145.suppl_1.067 [DOI] [Google Scholar]
68. Berry AS, Jones L, Sturm AC, Gidding S, Oetjens MT. Abstract 068: investigation of familial hypercholesterolemia subtypes in the UK biobank. Circulation. 2022;145:A068. doi: 10.1161/circ.145.suppl_1.068 [DOI] [Google Scholar]
69. Hennessy S, Penko J, Coxson P, Wei P, Atum A, Boylan R, Bibbins‐Domingo K. Abstract 069: missed opportunities for the control of hypertension in premenopausal women in the US. Circulation. 2022;145:A069. doi: 10.1161/circ.145.suppl_1.069 [DOI] [Google Scholar]
70. Omole TD, Garrard W, Mulukutla SR, Thoma FW, Zhu J, Magnani JW. Abstract 070: area deprivation index is associated with oral anticoagulation provision in incident atrial fibrillation. Circulation. 2022;145:A070. doi: 10.1161/circ.145.suppl_1.070 [DOI] [PMC free article] [PubMed] [Google Scholar]
71. Heilman A, Warsavage T, Liu W, Raghavan S. Abstract 071: gaps in statin initiation and target lipid reduction arise early after diabetes diagnosis. Circulation. 2022;145:A071. doi: 10.1161/circ.145.suppl_1.071 [DOI] [Google Scholar]
72. Hammond MM, Cameron N, Bah I, Beltrame K, Khan S, Shah NS. Abstract 072: statin eligibility and use for primary prevention among US adults across strata of atherosclerotic cardiovascular disease risk. Circulation. 2022;145:A072. doi: 10.1161/circ.145.suppl_1.072 [DOI] [PMC free article] [PubMed] [Google Scholar]
73. Makarem N, Chau K, Miller EC, Gyamfi‐Bannerman C, Tous I, Booker WA, Catov JM, Haas D, Grobman W, Levine L, et al. Abstract 073: a mediterranean diet pattern is associated with lower risk of adverse pregnancy outcomes in US women: results from the NuMoM2b cohort. Circulation. 2022;145. doi: 10.1161/circ.145.suppl_1.073 [DOI] [PMC free article] [PubMed] [Google Scholar]
74. Scott J, Hauspurg A, Muldoon MF, Davis EM, Catov JM. Abstract 075: sociodemographic and pregnancy related differences in blood pressure phenotypes a decade following pregnancy. Circulation. 2022;145:A075. doi: 10.1161/circ.145.suppl_1.075 [DOI] [Google Scholar]
75. Wang L, Morelen D, Alamian A. Abstract 077: association between key family and individual factors and the risk of obesity in offspring: findings from a prospective cohort study. Circulation. 2022;145:A077. doi: 10.1161/circ.145.suppl_1.077 [DOI] [PMC free article] [PubMed] [Google Scholar]
76. Kohler RA, Poffenberger P, lilly C, Pyles LA. Abstract 078: mid‐ to long‐ term follow‐up care insufficiencies from a cross‐sectional school‐ based cholesterol screening program. Circulation. 2022;145:A078.doi: 10.1161/circ.145.suppl_1.078 [Google Scholar]
77. Acevedo‐Fontanez A, Cvejkus R, zmuda j, Wheeler V, Rosano C, Miljkovic I, Kuipers AL. Abstract MP22: myosteatosis is associated with worse cognition in African Caribbean women. Circulation. 2022;145:AMP22. doi: 10.1161/circ.145.suppl_1.MP22 [DOI] [Google Scholar]
78. Molinsky R, Ikramuddin S, Siddiqui F, Demmer R. Abstract P168: the association between bariatric surgery and cardiometabolic risk factors: the National Health and Nutrition Examination Survey. Circulation. 2022;145:AP168. doi: 10.1161/circ.145.suppl_1.P168 [DOI] [Google Scholar]
79. Anthony KM, Trani E; Monbureau TO , Hill MJM, Loehr LR, Harris KM, Aiello AE, Hummer RA, Whitsel EA. Abstract P154: reliability of cardiovascular disease surveillance in the National Longitudinal Study of Adolescent to Adult Health. Circulation. 2022;145:AP154. doi: 10.1161/circ.145.suppl_1.P154 [DOI] [Google Scholar]
80. Tristao Parra M, Sada I, Gold R, Eastman A, Vella CA, Price C, Miljkovic I, Allison MA. Abstract P087: distinct associations between abdominal muscle density and area with N‐terminal pro‐b‐type natriuretic peptide among Mesa participants. Circulation. 2022;145:AP087. doi: 10.1161/circ.145.suppl_1.P087 [DOI] [Google Scholar]
81. Peter KM, Evenson KR, Cuthbertson C, Howard AGG, Lee Im M. Abstract MP27: associations of accelerometer‐measured physical activity and sedentary behavior with incident ischemic stroke: the Women's health study (WHS). Circulation. 2022;145:AMP27. doi: 10.1161/circ.145.suppl_1.MP27 [DOI] [Google Scholar]
82. Booker R, Newton RL, Norris KC, Thorpe RJ, Carnethon MR, Holmes ME. Abstract P075: an innovative statistical approach to investigate the association of movement behaviors on high‐sensitivity C‐reactive protein: the Jackson heart study. Circulation. 2022;145:AP075. doi: 10.1161/circ.145.suppl_1.P075 [DOI] [PMC free article] [PubMed] [Google Scholar]
83. Cammack AL, Suglia SF. Abstract MP44: adolescent team sports participation, adiposity, and inflammation among young adult child maltreatment survivors. Circulation. 2022;145:AMP44. doi: 10.1161/circ.145.suppl_1.MP44 [DOI] [Google Scholar]
84. Cory H, Mason S, Slaughter‐Acey J, Neumark‐Sztainer D. Abstract MP69: adolescent experiences of racism: associations with cardiovascular disease risk‐related behaviors in a diverse population‐based sample. Circulation. 2022;145:AMP69. doi: 10.1161/circ.145.suppl_1.MP69 [DOI] [Google Scholar]
85. Burnette B, Hazzard V, Hahn S, Neumark‐Sztainer DR. Abstract P209: like parent, like child? Examining associations among parent and emerging adult intuitive eating. Circulation. 2022;145:AP209. doi: 10.1161/circ.145.suppl_1.P209 [DOI] [Google Scholar]
86. Taher S, Wong M, Carnethon MR, Kandula N, Kiefe CI, Kershaw K. Abstract MP04: food insecurity and blood pressure control: the coronary artery risk in young adults (CARDIA) study. Circulation. 2022;145:AMP04. doi: 10.1161/circ.145.suppl_1.MP04 [DOI] [Google Scholar]
87. Petrea RE, Kojis D, Scott MR, Beiser AS, Romero JR, De Carli C, Seshadri S. Abstract MP62: sex‐specific associations of vascular risk factors and brain MRI measures in the Framingham offspring. Circulation. 2022;145:AMP62. doi: 10.1161/circ.145.suppl_1.MP62 [DOI] [Google Scholar]
88. Mendoza CE, Faurot KR, Lash J, Sotres‐Alvarez D, Daviglus ML, Heiss GM. Abstract P022: MS #279 ‐ use of dietary supplements and risk of chronic kidney disease in the Hispanic community health study/study of Latinos (HCHS/SOL). Circulation. 2022;145:AP022. doi: 10.1161/circ.145.suppl_1.P022 [DOI] [Google Scholar]

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[jah38304-bib-0049] 49. Heianza Y, Xue Q, Rood J, Clish C, Bray G, Sacks F, Qi L. Abstract 048: changes in bile acid metabolism, circulating microRNA‐34a, and improvements in lipid profiles in response to weight‐loss diets: the pounds lost trial. Circulation. 2022;145:A048. doi: 10.1161/circ.145.suppl_1.048 [DOI] [Google Scholar]

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[jah38304-bib-0051] 51. de Brito JN, Pereira MA, Kelly AS, Erickson DJ, Sherwood NE, Mason SM, Loth KA, French S, Kunin‐Batson A. Abstract 051: association between body mass index trajectories from early to middle childhood and biomarkers of cardiometabolic risk among children living in low‐income and racially/ethnically diverse households. Circulation. 2022;145:A051. doi: 10.1161/circ.145.suppl_1.051 [DOI] [Google Scholar]

[jah38304-bib-0052] 52. Akinyelure OP, Jaeger BC, Oparil S, Carson AP, Safford M, Howard G, Muntner P, Hardy ST. Abstract 052: social determinants of health and uncontrolled blood pressure in a National Cohort of Black and White US adults. Circulation. 2022;145:A052. doi: 10.1161/circ.145.suppl_1.052 [DOI] [PMC free article] [PubMed] [Google Scholar]

[jah38304-bib-0053] 53. Clarke AW, El Moudden I, Newby OM, Wood L, Dodani S. Abstract 053: heals med‐tech: a telehealth based behavioral lifestyle hypertension control program for high‐risk African Americans presenting at primary care clinics. Circulation. 2022;145:A053. doi: 10.1161/circ.145.suppl_1.053 [DOI] [Google Scholar]

[jah38304-bib-0054] 54. April‐Sanders AK, Golestaneh L, Zhang L, Swett K, Meissner P, Bellin EY, Rodriguez C. Abstract 054: hypertension treatment and control in a New York city healthcare system. Circulation. 2022;145:A054. doi: 10.1161/circ.145.suppl_1.054 [DOI] [PMC free article] [PubMed] [Google Scholar]

[jah38304-bib-0055] 55. Sims KD, Hystad PW, Batty GD, Smit E, McGregor JC, Odden MC. Abstract 055: neighborhood‐wide association study of hypertension in the health and retirement study. Circulation. 2022;145:A055. doi: 10.1161/circ.145.suppl_1.055 [DOI] [Google Scholar]

[jah38304-bib-0056] 56. Plante TB, Juraschek SP, Howard G, Howard VJ, Tracy RP, Judd SE, Kamin Mukaz D, Zakai NA, Long DL, Cushman M. Abstract 056: inflammatory cytokines and incident hypertension in the REasons for geographic and racial differences in stroke (REGARDS) study. Circulation. 2022;145:A056. doi: 10.1161/circ.145.suppl_1.056 [DOI] [Google Scholar]

[jah38304-bib-0057] 57. Odden MC, Li Y, Graham L, Steinman M, Lee S, Marcum Z, Liu C, Jing B, Fung K, Peralta CA. Abstract 057: trends in blood pressure diagnosis, treatment, and control among nursing home residents, 2007–2018. Circulation. 2022;145:A057. doi: 10.1161/circ.145.suppl_1.057 [DOI] [PMC free article] [PubMed] [Google Scholar]

[jah38304-bib-0058] 58. Ogungbe O, Kumbe B, Fadodun OTL, Meyer D, Asala A, Davidson P, Dennison Himmelfarb C, Post W, Commodore‐mensah Y. Abstract 058: subclinical myocardial injury, coagulopathy, and inflammation in Covid‐19: a meta‐analysis. Circulation. 2022;145:A058. doi: 10.1161/circ.145.suppl_1.058 [DOI] [PMC free article] [PubMed] [Google Scholar]

[jah38304-bib-0059] 59. Rivera A, Al‐Heeti O, Petito L, Williams JL, Feinstein MJ, Taiwo B, Achenbach C. Abstract 060: association of antecedent statin use with outcomes of people with Covid‐19 admitted at northwestern medicine health system. Circulation. 2022;145:A060. doi: 10.1161/circ.145.suppl_1.060 [DOI] [Google Scholar]

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[jah38304-bib-0061] 61. Patel S, Visotcky A, Devine A, Kode V, Kotlo S, Aljadah M, Sparapani R, Kulinski JP. Abstract 059: COVID‐19 and type II NSTEMI: a comprehensive overview. Circulation. 2022;145:A059. doi: 10.1161/circ.145.suppl_1.059 [DOI] [Google Scholar]

[jah38304-bib-0062] 62. Lee M, Whitsel EA, Avery CL, Hughes TM, Griswold M, Sedaghat S, Gottesman RF, Mosley T, Heiss GM, Lutsey PL. Abstract 062: racial and ethnic differences in the population burden of dementia attributable to modifiable risk factors in the United States. Circulation. 2022;145:A062. doi: 10.1161/circ.145.suppl_1.062 [DOI] [Google Scholar]

[jah38304-bib-0063] 63. Schaich CL, Bancks M, Hayden K, Ding J, Rapp S, Bertoni AG, Fitzpatrick AL, Heckbert SR, Hughes TM, Mongraw‐chaffin M. Abstract 063: higher visit‐to‐visit variability in fasting glucose and HbA1c is associated with decline in global cognitive performance: the multi‐ethnic study of atherosclerosis (MESA). Circulation. 2022;145:A063. doi: 10.1161/circ.145.suppl_1.063 [DOI] [Google Scholar]

[jah38304-bib-0064] 64. Liu C, Ma Y, Hofman A, Waziry R, Koton S, Pike JR, Windham BG, Power MC, Sharrett AR, Gottesman RF. Abstract 065: educational attainment and dementia risk: mediation by vascular risk factors at mid‐life in the atherosclerosis risk in communities (ARIC) study. Circulation. 2022;145:A065. doi: 10.1161/circ.145.suppl_1.065 [DOI] [Google Scholar]

[jah38304-bib-0065] 65. Liu X, Dhana K, Barnes L, Tangney C, Aggarwal P, Agarwal N, Holland T, Rajan K. Abstract 066: a healthy plant‐based diet was associated with slower cognitive decline in African Americans: a biracial community‐based cohort of older adults. Circulation. 2022;145:A066. doi: 10.1161/circ.145.suppl_1.066 [DOI] [PMC free article] [PubMed] [Google Scholar]

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[jah38304-bib-0067] 67. Wang FM, Yebyo HG, Boyd C, Puhan MA, Matsushita K, Blaha MJ, Schoenborn N. Abstract 067: outcome preferences related to cardiovascular preventive therapies in older adults: an online survey. Circulation. 2022;145:A067. doi: 10.1161/circ.145.suppl_1.067 [DOI] [Google Scholar]

[jah38304-bib-0068] 68. Berry AS, Jones L, Sturm AC, Gidding S, Oetjens MT. Abstract 068: investigation of familial hypercholesterolemia subtypes in the UK biobank. Circulation. 2022;145:A068. doi: 10.1161/circ.145.suppl_1.068 [DOI] [Google Scholar]

[jah38304-bib-0069] 69. Hennessy S, Penko J, Coxson P, Wei P, Atum A, Boylan R, Bibbins‐Domingo K. Abstract 069: missed opportunities for the control of hypertension in premenopausal women in the US. Circulation. 2022;145:A069. doi: 10.1161/circ.145.suppl_1.069 [DOI] [Google Scholar]

[jah38304-bib-0070] 70. Omole TD, Garrard W, Mulukutla SR, Thoma FW, Zhu J, Magnani JW. Abstract 070: area deprivation index is associated with oral anticoagulation provision in incident atrial fibrillation. Circulation. 2022;145:A070. doi: 10.1161/circ.145.suppl_1.070 [DOI] [PMC free article] [PubMed] [Google Scholar]

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[jah38304-bib-0074] 74. Scott J, Hauspurg A, Muldoon MF, Davis EM, Catov JM. Abstract 075: sociodemographic and pregnancy related differences in blood pressure phenotypes a decade following pregnancy. Circulation. 2022;145:A075. doi: 10.1161/circ.145.suppl_1.075 [DOI] [Google Scholar]

[jah38304-bib-0075] 75. Wang L, Morelen D, Alamian A. Abstract 077: association between key family and individual factors and the risk of obesity in offspring: findings from a prospective cohort study. Circulation. 2022;145:A077. doi: 10.1161/circ.145.suppl_1.077 [DOI] [PMC free article] [PubMed] [Google Scholar]

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[jah38304-bib-0077] 77. Acevedo‐Fontanez A, Cvejkus R, zmuda j, Wheeler V, Rosano C, Miljkovic I, Kuipers AL. Abstract MP22: myosteatosis is associated with worse cognition in African Caribbean women. Circulation. 2022;145:AMP22. doi: 10.1161/circ.145.suppl_1.MP22 [DOI] [Google Scholar]

[jah38304-bib-0078] 78. Molinsky R, Ikramuddin S, Siddiqui F, Demmer R. Abstract P168: the association between bariatric surgery and cardiometabolic risk factors: the National Health and Nutrition Examination Survey. Circulation. 2022;145:AP168. doi: 10.1161/circ.145.suppl_1.P168 [DOI] [Google Scholar]

[jah38304-bib-0079] 79. Anthony KM, Trani E; Monbureau TO , Hill MJM, Loehr LR, Harris KM, Aiello AE, Hummer RA, Whitsel EA. Abstract P154: reliability of cardiovascular disease surveillance in the National Longitudinal Study of Adolescent to Adult Health. Circulation. 2022;145:AP154. doi: 10.1161/circ.145.suppl_1.P154 [DOI] [Google Scholar]

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PERMALINK

American Heart Association EPI|Lifestyle Scientific Sessions: 2022 Meeting Highlights

Elisabeth L P Sattler, PhD, RPh

Oluwabunmi Ogungbe, PhD, MPH, RN

Amelia S Wallace, PhD, MS

Zahra Aryan, MD, MPH

Noelle Castilla‐Ojo, BS

Jin Dai, MS

Ileana De Anda‐Duran, MD, MPH

Kathryn Foti, PhD, MPH

Charles A German, MD, MS

Eric T Hyde, MPH

Scott R Jafarian‐Kerman, MD, MSCI

Karla N Kendrick, MD, MPH

Ben King, PhD, MPH

Adam Edward Lang, PharmD

Olive Tang, MD, PhD

Ruth‐Alma Turkson‐Ocran, PhD, MPH, APRN

Luis A Rodriguez, PhD, MPH, RD

Frances M Wang, PhD, MS

Mingyu Zhang PhD, MHS

Marie‐France Hivert, MD, MMSc

Pamela L Lutsey, PhD, MPH

AHA'S CONTINUED INVESTMENT IN HEALTH EQUITY AND SOCIAL JUSTICE

KEYNOTE SESSIONS

MEMORIAL LECTURES AND SPECIAL SESSIONS

David Kritchevsky Memorial Lecture

Richard D. Remington Methodology Lecture

William B. Kannel, MD Memorial Lectureship in Preventive Cardiology

AHA Scientific Updates

American Society for Preventive Cardiology Annual Debate

ORAL ABSTRACT PRESENTATIONS

Social Determinants and Health Disparities

Diabetes and Obesity

Recent Advances in Omics

Nutrition

Novel Risk Factors

Physical Activity and Sleep

Jeremiah and Rose Stamler Research Award for New Investigators Finalist Presentations

Biomarkers and Risk Prediction

Hypertension

COVID‐19 Updates

Aging and Brain Health

Preventive Cardiology

Pregnancy/Maternal and Childhood

National Heart, Lung, and Blood Institute Cardiovascular Epidemiology, Biostatistics, and Prevention Trainee Session

EARLY CAREER COMMITTEE EVENTS

Rapid Fire Oral Abstracts

Table 1.

COUNCIL NETWORKING LUNCHEONS

Table 2.

Networking Roundtables

Table 3.

Council Awards

Table 4.

Table 5.

CONCLUSIONS

Sources of Funding

Disclosures

References

ACTIONS

PERMALINK

RESOURCES

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