Fig. 1.

Effect of protocatechuic acid on PPARγ, COX-2, NF-Κβ, and IKBKB proteins levels. The effect of treatment with protocatechuic acid (50, 100 mg/kg; p.o.) once daily for 10 consecutive days after cyclophosphamide (200 mg/kg; i.p.) single dose on a PPARγ b COX-2 c NF-Κβ d IKBKB proteins levels. The data were expressed as mean ± SD, (n = 8). Statistical analysis was carried out by one-way ANOVA followed by Tukey HSD test for multiple comparisons. ^aSignificantly different from normal control. ^bSignificantly different from cyclophosphamide control. ^cSignificantly different from cyclophosphamide + protocatechuic acid 50 mg/kg at P < 0.05