Table 1.

Selected neuropsychiatric disorders following SARS-CoV-2 infection

	Mood disorder	Anxiety disorder	Psychotic disorder	Brain fog
HR at 6 months versus other RTI (95% CI)	1.08 (1.06–1.11)	1.13 (1.11–1.15)	1.27 (1.18–1.37)	1.36 (1.33–1.39)
Incidence at 6 months (95% CI), %	2.95 (2.91–3.00)	4.98 (4.92–5.04)	0.20 (0.19–0.21)	2.65 (2.61–2.69)
Absolute risk increase at 6 months, %	0.15	0.37	0.036	0.64
Risk horizon, days	43	58	>730	>730
Time to equal incidence, days	457	417	>730	>730

Figures refer to first recorded diagnosis (i.e. people who had no diagnosis of that condition prior to infection). Incidence, hazard ratio (HR) and absolute risk increase are shown at 6 months compared to other respiratory tract infections (RTI). Risk horizon = the time at which the HR returns to 1. Time to equal incidence = the time when the cumulative number of diagnoses in the COVID-19 cohort is the same as the cumulative number of diagnoses in the comparator cohort. Diagnoses are ICD-10 codes: psychotic disorder (F20-F29), mood disorder (F30-F39), anxiety disorder (F40-F48). ‘Brain fog’ is a composite category²⁰ of diagnostic codes for dementia (F01-F03, G30, G31.0, G31.83), mild cognitive impairment (G31.84), delirium (F05), encephalopathy (G93.40), and R codes for symptoms and signs of attentional or cognitive dysfunction (R40, R41, R48); the majority of people in the brain fog category had the R41 code, ‘other cognitive symptoms’.¹⁵ The 95% CIs are shown in parentheses. Data are from Taquet et al.^15,20