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British Heart Journal logoLink to British Heart Journal
. 1990 Jan;63(1):22–25. doi: 10.1136/hrt.63.1.22

Effects of food on the central and peripheral haemodynamic response to upright exercise in normal volunteers.

J J Yi 1, L Fullwood 1, K Stainer 1, A J Cowley 1, J R Hampton 1
PMCID: PMC1024309  PMID: 2106910

Abstract

The central and peripheral haemodynamic effects of a modest meal were investigated in healthy volunteers at rest and in response to submaximal exercise. The meal increased heart rate, cardiac output, oxygen consumption, carbon dioxide production, and minute ventilation at rest and during exercise. The effects of food were additive to those induced by the exercise. Food had no effect on limb blood flow and lowered total systemic vascular resistance suggesting that there were no compensatory changes in regional blood flow to help redirect blood to the gut. An increase in cardiac output, and therefore myocardial work, is the predominant cardiovascular response to eating and this may help explain the postprandial deterioration in symptoms of some patients with cardiovascular disorders.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Cowley A. J., Rowley J. M., Stainer K., Hampton J. R. Effects of captopril on abnormalities of the peripheral circulation and respiratory function in patients with severe heart failure. Lancet. 1984 Nov 17;2(8412):1120–1124. doi: 10.1016/s0140-6736(84)91557-5. [DOI] [PubMed] [Google Scholar]
  2. Cowley A. J., Stainer K., Murphy D. T., Murphy J., Hampton J. R. A non-invasive method for measuring cardiac output: the effect of Christmas lunch. Lancet. 1986 Dec 20;2(8521-22):1422–1424. doi: 10.1016/s0140-6736(86)92734-0. [DOI] [PubMed] [Google Scholar]
  3. Cowley A. J., Stainer K., Rowley J. M., Hampton J. R. Abnormalities of the peripheral circulation and respiratory function in patients with severe heart failure. Br Heart J. 1986 Jan;55(1):75–80. doi: 10.1136/hrt.55.1.75. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. GREENFIELD A. D., WHITNEY R. J., MOWBRAY J. F. Methods for the investigation of peripheral blood flow. Br Med Bull. 1963 May;19:101–109. doi: 10.1093/oxfordjournals.bmb.a070026. [DOI] [PubMed] [Google Scholar]
  5. JONES W. B., THOMAS H. D., REEVES T. J. CIRCULATORY AND VENTILATORY RESPONSES TO POSTPRANDIAL EXERCISE. Am Heart J. 1965 May;69:668–676. doi: 10.1016/0002-8703(65)90249-8. [DOI] [PubMed] [Google Scholar]
  6. Kelbaek H., Munck O., Christensen N. J., Godtfredsen J. Autonomic nervous control of postprandial hemodynamic changes at rest and upright exercise. J Appl Physiol (1985) 1987 Nov;63(5):1862–1865. doi: 10.1152/jappl.1987.63.5.1862. [DOI] [PubMed] [Google Scholar]
  7. Kelbaek H., Munck O., Christensen N. J., Godtfredsen J. Central haemodynamic changes after a meal. Br Heart J. 1989 Jun;61(6):506–509. doi: 10.1136/hrt.61.6.506. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Mason D. T., Zelis R., Longhurst J., Lee G. Cardiocirculatory responses to muscular exercise in congestive heart failure. Prog Cardiovasc Dis. 1977 May-Jun;19(6):475–489. doi: 10.1016/0033-0620(77)90011-1. [DOI] [PubMed] [Google Scholar]
  9. Qamar M. I., Read A. E., Skidmore R., Evans J. M., Wells P. N. Transcutaneous Doppler ultrasound measurement of superior mesenteric artery blood flow in man. Gut. 1986 Jan;27(1):100–105. doi: 10.1136/gut.27.1.100. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. de Mey C., Hansen-Schmidt S., Enterling D. Postprandial haemodynamic changes: a source of bias in cardiovascular research affected by its own methodological bias. Cardiovasc Res. 1988 Oct;22(10):703–707. doi: 10.1093/cvr/22.10.703. [DOI] [PubMed] [Google Scholar]

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