Abstract
Conspicuous left axis deviation was found in two thirds (27 patients) of 44 children with a perimembranous ventricular septal defect, echocardiographic signs of apposition of the septal tricuspid valve leaflet, and an aneurysm of the membranous septum. In 10 patients earlier electrocardiograms did not show left axis deviation; this feature appeared when the aneurysm of the membranous septum was first seen on the echocardiogram. None of the 44 controls with perimembranous ventricular septal defect but without an aneurysm had left axis deviation. This study suggests that the appearances of conspicuous left axis deviation in a patient with ventricular septal defect indicate a spontaneous reduction in the defect by apposition of the septal tricuspid valve leaflet and by the formation of an aneurysm of the membranous septum.
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- AGUSTSSON M. H., ARCILLA R. A., BICOFF J. P., MONCADA R., GASUL B. M. Spontaneous functional closure of ventricular septal defects in fourteen children demonstrated by serial cardiac catheterizations and angiocardiography. Pediatrics. 1963 Jun;31:958–968. [PubMed] [Google Scholar]
- Anderson R. H., Lenox C. C., Zuberbuhler J. R. Mechanisms of closure of perimembranous ventricular septal defect. Am J Cardiol. 1983 Aug;52(3):341–345. doi: 10.1016/0002-9149(83)90135-2. [DOI] [PubMed] [Google Scholar]
- BARON M. G., WOLF B. S., GRISHMAN A., VANMIEROP L. H. ANEURYSM OF THE MEMBRANOUS SEPTUM. Am J Roentgenol Radium Ther Nucl Med. 1964 Jun;91:1303–1314. [PubMed] [Google Scholar]
- BLOOMFIELD D. K. THE NATURAL HISTORY OF VENTRICULAR SEPTAL DEFECT IN PATIENTS SURVIVING INFANCY. Circulation. 1964 Jun;29:914–955. doi: 10.1161/01.cir.29.6.914. [DOI] [PubMed] [Google Scholar]
- Beerman L. B., Park S. C., Fischer D. R., Fricker F. J., Mathews R. A., Neches W. H., Lenox C. C., Zuberbuhler J. R. Ventricular septal defect associated with aneurysm of the membranous septum. J Am Coll Cardiol. 1985 Jan;5(1):118–123. doi: 10.1016/s0735-1097(85)80093-0. [DOI] [PubMed] [Google Scholar]
- Bäckman H. Influence of structural and functional features of ventricular septal defect on frontal plane QRS axis of the electrocardiogram. Br Heart J. 1972 Mar;34(3):274–283. doi: 10.1136/hrt.34.3.274. [DOI] [PMC free article] [PubMed] [Google Scholar]
- CLARK R. J., WHITE P. D. Congenital aneurysmal defect of the membranous portion of the ventricular septum associated with heart block, ventricular flutter, Adams-Stokes syndrome and death. Circulation. 1952 May;5(5):725–729. doi: 10.1161/01.cir.5.5.725. [DOI] [PubMed] [Google Scholar]
- Campbell M. Natural history of ventricular septal defect. Br Heart J. 1971 Mar;33(2):246–257. doi: 10.1136/hrt.33.2.246. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Canale J. M., Sahn D. J., Valdes-Cruz L. M., Allen H. D., Goldberg S. J., Ovitt T. W. Accuracy of two-dimensional echocardiography in the detection of aneurysms of the ventricular septum. Am Heart J. 1981 Mar;101(3):255–259. doi: 10.1016/0002-8703(81)90186-1. [DOI] [PubMed] [Google Scholar]
- Chesler E., Korns M. E., Edwards J. E. Anomalies of the tricuspid valve, including pouches, resembling aneurysms of the membranous ventricular septum. Am J Cardiol. 1968 May;21(5):661–668. doi: 10.1016/0002-9149(68)90263-4. [DOI] [PubMed] [Google Scholar]
- Edelstein J., Charms B. L. Ventricular septal aneurysms. A report of two cases. Circulation. 1965 Dec;32(6):981–984. doi: 10.1161/01.cir.32.6.981. [DOI] [PubMed] [Google Scholar]
- Eshaghpour E., Kawai N., Linhart J. W. Tricuspid insufficiency associated with aneurysm of the ventricular septum. Pediatrics. 1978 Apr;61(4):586–592. [PubMed] [Google Scholar]
- Freedom R. M., White R. D., Pieroni D. R., Varghese P. J., Krovetz L. J., Rowe R. D. The natural history of the so-called aneurysm of the membranous ventricular septum in childhood. Circulation. 1974 Feb;49(2):375–384. doi: 10.1161/01.cir.49.2.375. [DOI] [PubMed] [Google Scholar]
- GUP A. M., FRANKLIN R. B., HILL J. E., Jr THE VECTORCARDIOGRAM IN CHILDREN WITH LEFT AXIS DEVIATION AND NO APPARENT HEART DISEASE. Am Heart J. 1965 May;69:619–623. doi: 10.1016/0002-8703(65)90243-7. [DOI] [PubMed] [Google Scholar]
- HEGGTVEIT H. A. CONGENITAL ANEURYSM OF THE MEMBRANOUS SEPTUM ASSOCIATED WITH BUNDLE BRANCH BLOCK. Am J Cardiol. 1964 Jul;14:112–117. doi: 10.1016/0002-9149(64)90115-8. [DOI] [PubMed] [Google Scholar]
- Hoffman J. I., Rudolph A. M. The natural history of isolated ventricular septal defect with special reference to selection of patients for surgery. Adv Pediatr. 1970;17:57–79. [PubMed] [Google Scholar]
- Hoffman J. I., Rudolph A. M. The natural history of ventricular septal defects in infancy. Am J Cardiol. 1965 Nov;16(5):634–653. doi: 10.1016/0002-9149(65)90047-0. [DOI] [PubMed] [Google Scholar]
- Jain A. C., Rosenthal R. Aneurysm of the membranous ventricular septum. Br Heart J. 1967 Jan;29(1):60–63. doi: 10.1136/hrt.29.1.60. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LARSEN K. A., NOER T. Cardiac aneurysm of the membranous portion of the interventricular septum. Acta Med Scand. 1960 Apr 20;166:401–405. doi: 10.1111/j.0954-6820.1960.tb17395.x. [DOI] [PubMed] [Google Scholar]
- McCue C. M., Mantakas M. E., Tingelstad J. B., Ruddy S. Congenital heart block in newborns of mothers with connective tissue disease. Circulation. 1977 Jul;56(1):82–90. doi: 10.1161/01.cir.56.1.82. [DOI] [PubMed] [Google Scholar]
- Pombo E., Pilapil V. R., Lehan P. H. Aneurysm of the membranous ventricular septum. Am Heart J. 1970 Feb;79(2):188–193. doi: 10.1016/0002-8703(70)90308-x. [DOI] [PubMed] [Google Scholar]
- Ramaciotti C., Keren A., Silverman N. H. Importance of (perimembranous) ventricular septal aneurysm in the natural history of isolated perimembranous ventricular septal defect. Am J Cardiol. 1986 Feb 1;57(4):268–272. doi: 10.1016/0002-9149(86)90903-3. [DOI] [PubMed] [Google Scholar]
- SHUMACKER H. B., Jr, GLOVER J. CONGENITAL ANEURYSMS OF THE VENTRICULAR SEPTUM. Am Heart J. 1963 Sep;66:405–408. doi: 10.1016/0002-8703(63)90274-6. [DOI] [PubMed] [Google Scholar]
- STEINBERG I. Diagnosis of congenital aneurysm of the ventricular septum during life. Br Heart J. 1957 Jan;19(1):8–12. doi: 10.1136/hrt.19.1.8. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Snider A. R., Silverman N. H., Schiller N. B., Ports T. A. Echocardiographic evaluation of ventricular septal aneurysms. Circulation. 1979 May;59(5):920–926. doi: 10.1161/01.cir.59.5.920. [DOI] [PubMed] [Google Scholar]
- Tandon R., Edwards J. E. Aneurysmlike formations in relation to membranous ventricular septum. Circulation. 1973 May;47(5):1089–1097. doi: 10.1161/01.cir.47.5.1089. [DOI] [PubMed] [Google Scholar]
- Varghese P. J., Izukawa T., Celermajer J., Simon A., Rowe R. D. Aneurysm of the membranous ventricular septum. A method of spontaneous closure of small ventricular septal defect. Am J Cardiol. 1969 Oct;24(4):531–536. doi: 10.1016/0002-9149(69)90496-2. [DOI] [PubMed] [Google Scholar]





