Skip to main content
NCBI home page
British Heart Journal logoLink to British Heart Journal
. 1992 Jan;67(1):34–38. doi: 10.1136/hrt.67.1.34

Progress in familial hypertrophic cardiomyopathy: molecular genetic analyses in the original family studied by Teare.

H Watkins 1, C E Seidman 1, C MacRae 1, J G Seidman 1, W McKenna 1
PMCID: PMC1024696  PMID: 1739523

Full text

PDF
34

Images in this article

36Image
on p.36

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Antonarakis S. E. Diagnosis of genetic disorders at the DNA level. N Engl J Med. 1989 Jan 19;320(3):153–163. doi: 10.1056/NEJM198901193200305. [DOI] [PubMed] [Google Scholar]
  2. Ciró E., Nichols P. F., 3rd, Maron B. J. Heterogeneous morphologic expression of genetically transmitted hypertrophic cardiomyopathy. Two-dimensional echocardiographic analysis. Circulation. 1983 Jun;67(6):1227–1233. doi: 10.1161/01.cir.67.6.1227. [DOI] [PubMed] [Google Scholar]
  3. Geisterfer-Lowrance A. A., Kass S., Tanigawa G., Vosberg H. P., McKenna W., Seidman C. E., Seidman J. G. A molecular basis for familial hypertrophic cardiomyopathy: a beta cardiac myosin heavy chain gene missense mutation. Cell. 1990 Sep 7;62(5):999–1006. doi: 10.1016/0092-8674(90)90274-i. [DOI] [PubMed] [Google Scholar]
  4. Greaves S. C., Roche A. H., Neutze J. M., Whitlock R. M., Veale A. M. Inheritance of hypertrophic cardiomyopathy: a cross sectional and M mode echocardiographic study of 50 families. Br Heart J. 1987 Sep;58(3):259–266. doi: 10.1136/hrt.58.3.259. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Jarcho J. A., McKenna W., Pare J. A., Solomon S. D., Holcombe R. F., Dickie S., Levi T., Donis-Keller H., Seidman J. G., Seidman C. E. Mapping a gene for familial hypertrophic cardiomyopathy to chromosome 14q1. N Engl J Med. 1989 Nov 16;321(20):1372–1378. doi: 10.1056/NEJM198911163212005. [DOI] [PubMed] [Google Scholar]
  6. Maron B. J., Bonow R. O., Cannon R. O., 3rd, Leon M. B., Epstein S. E. Hypertrophic cardiomyopathy. Interrelations of clinical manifestations, pathophysiology, and therapy (1). N Engl J Med. 1987 Mar 26;316(13):780–789. doi: 10.1056/NEJM198703263161305. [DOI] [PubMed] [Google Scholar]
  7. Maron B. J., Lipson L. C., Roberts W. C., Savage D. D., Epstein S. E. "Malignant" hypertrophic cardiomyopathy: identification of a subgroup of families with unusually frequent premature death. Am J Cardiol. 1978 Jun;41(7):1133–1140. doi: 10.1016/0002-9149(78)90870-6. [DOI] [PubMed] [Google Scholar]
  8. Maron B. J., Nichols P. F., 3rd, Pickle L. W., Wesley Y. E., Mulvihill J. J. Patterns of inheritance in hypertrophic cardiomyopathy: assessment by M-mode and two-dimensional echocardiography. Am J Cardiol. 1984 Apr 1;53(8):1087–1094. doi: 10.1016/0002-9149(84)90643-x. [DOI] [PubMed] [Google Scholar]
  9. Maron B. J., Spirito P., Wesley Y., Arce J. Development and progression of left ventricular hypertrophy in children with hypertrophic cardiomyopathy. N Engl J Med. 1986 Sep 4;315(10):610–614. doi: 10.1056/NEJM198609043151003. [DOI] [PubMed] [Google Scholar]
  10. McKenna W. J., Stewart J. T., Nihoyannopoulos P., McGinty F., Davies M. J. Hypertrophic cardiomyopathy without hypertrophy: two families with myocardial disarray in the absence of increased myocardial mass. Br Heart J. 1990 May;63(5):287–290. doi: 10.1136/hrt.63.5.287. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. McKenna W., Deanfield J., Faruqui A., England D., Oakley C., Goodwin J. Prognosis in hypertrophic cardiomyopathy: role of age and clinical, electrocardiographic and hemodynamic features. Am J Cardiol. 1981 Mar;47(3):532–538. doi: 10.1016/0002-9149(81)90535-x. [DOI] [PubMed] [Google Scholar]
  12. Rosenzweig A., Watkins H., Hwang D. S., Miri M., McKenna W., Traill T. A., Seidman J. G., Seidman C. E. Preclinical diagnosis of familial hypertrophic cardiomyopathy by genetic analysis of blood lymphocytes. N Engl J Med. 1991 Dec 19;325(25):1753–1760. doi: 10.1056/NEJM199112193252501. [DOI] [PubMed] [Google Scholar]
  13. Solomon S. D., Geisterfer-Lowrance A. A., Vosberg H. P., Hiller G., Jarcho J. A., Morton C. C., McBride W. O., Mitchell A. L., Bale A. E., McKenna W. J. A locus for familial hypertrophic cardiomyopathy is closely linked to the cardiac myosin heavy chain genes, CRI-L436, and CRI-L329 on chromosome 14 at q11-q12. Am J Hum Genet. 1990 Sep;47(3):389–394. [PMC free article] [PubMed] [Google Scholar]
  14. Solomon S. D., Jarcho J. A., McKenna W., Geisterfer-Lowrance A., Germain R., Salerni R., Seidman J. G., Seidman C. E. Familial hypertrophic cardiomyopathy is a genetically heterogeneous disease. J Clin Invest. 1990 Sep;86(3):993–999. doi: 10.1172/JCI114802. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. TEARE D. Asymmetrical hypertrophy of the heart in young adults. Br Heart J. 1958 Jan;20(1):1–8. doi: 10.1136/hrt.20.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Tanigawa G., Jarcho J. A., Kass S., Solomon S. D., Vosberg H. P., Seidman J. G., Seidman C. E. A molecular basis for familial hypertrophic cardiomyopathy: an alpha/beta cardiac myosin heavy chain hybrid gene. Cell. 1990 Sep 7;62(5):991–998. doi: 10.1016/0092-8674(90)90273-h. [DOI] [PubMed] [Google Scholar]

Articles from British Heart Journal are provided here courtesy of BMJ Publishing Group

RESOURCES