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. 1993 May;69(5):391–394. doi: 10.1136/hrt.69.5.391

Anticardiolipin antibodies in ischaemic heart disease: marker or myth?

K V Phadke 1, R A Phillips 1, D T Clarke 1, M Jones 1, P Naish 1, P Carson 1
PMCID: PMC1025099  PMID: 8518060

Abstract

OBJECTIVES--To assess the incidence and significance of anticardiolipin antibodies after myocardial infarction and in unstable angina. DESIGN--A prospective study of all patients under 60 admitted to the coronary care unit over a 12 month period with a diagnosis of acute myocardial infarction who were followed up for a further 12 months. Patients admitted with unstable angina were similarly assessed but not followed up. Anticardiolipin antibody concentrations were compared with those of age matched controls. SETTING--A district general hospital. PATIENTS--307 patients with acute myocardial infarction and 160 patients with unstable angina. RESULTS--Anticardiolipin antibody concentrations in the two patient groups did not differ significantly from those in the control groups. Antibody concentrations were not related to a history of angina or myocardial infarction nor were they related to subsequent cardiovascular complications. CONCLUSION--This study shows no significant association between anticardiolipin antibody concentrations and either myocardial infarction or unstable angina.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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