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Gene, antibody, and stem-cell therapeutic approaches: (a) Antisense oligonucleotides, (b) Viral vectors delivering RNA interference or CRISPER/Cas9, (c) Monoclonal antibody, and (d) Stem cell transplantation. ANTX2: Ataxin-2; BM-MSC: bone-marrow-derived mesenchymal stem cells; C9orf72: Chromosome 9 open reading frame 72; FUS: Fused in sarcoma; SOD1: Superoxide dismutase 1. Created by Laura Tzeplaeff with “BioRender.com”.
