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. 1993 Nov;70(5):448–456. doi: 10.1136/hrt.70.5.448

Comparison of acoustic quantification and Doppler echocardiography in assessment of left ventricular diastolic variables.

A Chenzbraun 1, F J Pinto 1, S Popylisen 1, I Schnittger 1, R L Popp 1
PMCID: PMC1025358  PMID: 8260277

Abstract

OBJECTIVE--To assess the haemodynamic correlations of the waveforms of left ventricular area change obtained by automated boundary detection with newly developed acoustic quantification technology. DESIGN--The timing of events in the cardiac cycle was identified on the wave-form automated boundary detection and was correlated with the corresponding timing derived from pulsed wave Doppler flow velocity traces of the mitral valve and left ventricular outflow tract. The amounts of area change during the rapid filling phase and during atrial contraction were correlated with the time-velocity integrals of early and late diastolic ventricular filling obtained from Doppler tracings of the mitral inflow. SETTING--A university medical school echocardiography laboratory. SUBJECTS--16 healthy volunteers and 19 patients referred for echocardiographic studies. RESULTS--A significant correlation was found between the methods for measurement of the time from the R wave to mitral valve opening (r = 0.72, p < 0.01), isovolumic relaxation time (r = 0.62, p < 0.01), and ejection time (r = 0.54, p < 0.01). The change of total area that occurred during rapid filling and atrial filling phases measured from the acoustic waveform correlated with the time-velocity integrals of the early and late diastolic mitral valve inflow velocity derived from Doppler echocardiography (r = 0.60 and r = 0.80, respectively). CONCLUSION--The waveform of left ventricular area obtained by the automated boundary detection technique identifies the phases of the cardiac cycle and correlates with Doppler values of left ventricular diastolic function. Therefore, this new method of automated boundary detection has potential uses in the assessment of left ventricular diastolic function.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Appleton C. P., Hatle L. K., Popp R. L. Relation of transmitral flow velocity patterns to left ventricular diastolic function: new insights from a combined hemodynamic and Doppler echocardiographic study. J Am Coll Cardiol. 1988 Aug;12(2):426–440. doi: 10.1016/0735-1097(88)90416-0. [DOI] [PubMed] [Google Scholar]
  2. Appleton C. P., Hatle L. K., Popp R. L. Relation of transmitral flow velocity patterns to left ventricular diastolic function: new insights from a combined hemodynamic and Doppler echocardiographic study. J Am Coll Cardiol. 1988 Aug;12(2):426–440. doi: 10.1016/0735-1097(88)90416-0. [DOI] [PubMed] [Google Scholar]
  3. Bland J. M., Altman D. G. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986 Feb 8;1(8476):307–310. [PubMed] [Google Scholar]
  4. Bonow R. O. Radionuclide angiographic evaluation of left ventricular diastolic function. Circulation. 1991 Sep;84(3 Suppl):I208–I215. [PubMed] [Google Scholar]
  5. Choong C. Y., Abascal V. M., Thomas J. D., Guerrero J. L., McGlew S., Weyman A. E. Combined influence of ventricular loading and relaxation on the transmitral flow velocity profile in dogs measured by Doppler echocardiography. Circulation. 1988 Sep;78(3):672–683. doi: 10.1161/01.cir.78.3.672. [DOI] [PubMed] [Google Scholar]
  6. Geiser E. A., Conetta D. A., Limacher M. C., Stockton V. O., Oliver L. H., Jones B. A second-generation computer-based edge detection algorithm for short-axis, two-dimensional echocardiographic images: accuracy and improvement in interobserver variability. J Am Soc Echocardiogr. 1990 Mar-Apr;3(2):79–90. doi: 10.1016/s0894-7317(14)80500-2. [DOI] [PubMed] [Google Scholar]
  7. Parisi A. F., Moynihan P. F., Feldman C. L., Folland E. D. Approaches to determination of left ventricular volume and ejection fraction by real-time two-dimensional echocardiography. Clin Cardiol. 1979 Aug;2(4):257–263. doi: 10.1002/clc.4960020404. [DOI] [PubMed] [Google Scholar]
  8. Pietro D. A., Voelkel A. G., Ray B. J., Parisi A. F. Reproducibility of echocardiography. A study evaluating the variability of serial echocardiographic measurements. Chest. 1981 Jan;79(1):29–32. doi: 10.1378/chest.79.1.29. [DOI] [PubMed] [Google Scholar]
  9. Pérez J. E., Waggoner A. D., Barzilai B., Melton H. E., Jr, Miller J. G., Sobel B. E. On-line assessment of ventricular function by automatic boundary detection and ultrasonic backscatter imaging. J Am Coll Cardiol. 1992 Feb;19(2):313–320. doi: 10.1016/0735-1097(92)90484-5. [DOI] [PubMed] [Google Scholar]
  10. Sasson Z., Hatle L., Appleton C. P., Jewett M., Alderman E. L., Popp R. L. Intraventricular flow during isovolumic relaxation: description and characterization by Doppler echocardiography. J Am Coll Cardiol. 1987 Sep;10(3):539–546. doi: 10.1016/s0735-1097(87)80196-1. [DOI] [PubMed] [Google Scholar]
  11. Spirito P., Maron B. J., Bonow R. O. Noninvasive assessment of left ventricular diastolic function: comparative analysis of Doppler echocardiographic and radionuclide angiographic techniques. J Am Coll Cardiol. 1986 Mar;7(3):518–526. doi: 10.1016/s0735-1097(86)80461-2. [DOI] [PubMed] [Google Scholar]
  12. Spirito P., Maron B. J. Doppler echocardiography for assessing left ventricular diastolic function. Ann Intern Med. 1988 Jul 15;109(2):122–126. doi: 10.7326/0003-4819-109-2-122. [DOI] [PubMed] [Google Scholar]
  13. Wyatt H. L., Meerbaum S., Heng M. K., Gueret P., Corday E. Cross-sectional echocardiography. III. Analysis of mathematic models for quantifying volume of symmetric and asymmetric left ventricles. Am Heart J. 1980 Dec;100(6 Pt 1):821–828. doi: 10.1016/0002-8703(80)90062-9. [DOI] [PubMed] [Google Scholar]

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