Skip to main content
NCBI home page
British Heart Journal logoLink to British Heart Journal
. 1992 Dec;68(6):560–566. doi: 10.1136/hrt.68.12.560

Effect of exercise training on the total ischaemic burden: an assessment by 24 hour ambulatory electrocardiographic monitoring

Iain C Todd 1, David Ballantyne 1
PMCID: PMC1025685  PMID: 1467049

Abstract

Objective—To examine the effect of prolonged high intensity exercise training on total ischaemic burden in men with chronic stable angina pectoris.

Design—A randomised controlled trial based on 24 hour ambulatory electrocardiographic monitoring of patients on two occasions a year apart.

Setting—Cardiology department of a large general hospital.

Subjects—40 men under 60 years of age with chronic stable angina pectoris and no previous myocardial infarction.

Results—After training the exercise group showed a 30% reduction in frequency of ST segment depression. There were significant reductions in painful episodes of ischaemia and those triggered by changes in heart rate. There was also a trend towards a reduction in silent ischaemia and episodes not triggered by changes in heart rate. The duration of ischaemic episodes was also reduced. No significant change in frequency or severity of dysrhythmia was shown.

Conclusions—Exercise training reduces total ischaemic burden in patients with angina pectoris by reducing the frequency and duration of all types of ischaemic episode.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Balasubramanian V., Lahiri A., Green H. L., Stott F. D., Raftery E. B. Ambulatory ST segment monitoring. Problems, pitfalls, solutions, and clinical application. Br Heart J. 1980 Oct;44(4):419–425. doi: 10.1136/hrt.44.4.419. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Calvert A., Lown B., Gorlin R. Ventricular premature beats and anatomically defined coronary heart disease. Am J Cardiol. 1977 May 4;39(5):627–634. doi: 10.1016/s0002-9149(77)80121-5. [DOI] [PubMed] [Google Scholar]
  3. Cecchi A. C., Dovellini E. V., Marchi F., Pucci P., Santoro G. M., Fazzini P. F. Silent myocardial ischemia during ambulatory electrocardiographic monitoring in patients with effort angina. J Am Coll Cardiol. 1983 Mar;1(3):934–939. doi: 10.1016/s0735-1097(83)80213-7. [DOI] [PubMed] [Google Scholar]
  4. Chierchia S., Gallino A., Smith G., Deanfield J., Morgan M., Croom M., Maseri A. Role of heart rate in pathophysiology of chronic stable angina. Lancet. 1984 Dec 15;2(8416):1353–1357. doi: 10.1016/s0140-6736(84)92055-5. [DOI] [PubMed] [Google Scholar]
  5. Deanfield J. E., Maseri A., Selwyn A. P., Ribeiro P., Chierchia S., Krikler S., Morgan M. Myocardial ischaemia during daily life in patients with stable angina: its relation to symptoms and heart rate changes. Lancet. 1983 Oct 1;2(8353):753–758. doi: 10.1016/s0140-6736(83)92295-x. [DOI] [PubMed] [Google Scholar]
  6. Hinkle L. E., Jr, Carver S. T., Stevens M. The frequency of asymptomatic disturbances of cardiac rhythm and conduction in middle-aged men. Am J Cardiol. 1969 Nov;24(5):629–650. doi: 10.1016/0002-9149(69)90451-2. [DOI] [PubMed] [Google Scholar]
  7. Knoebel S. B. President's page: On the occasion of the 25th year of the Journal of the American College of Cardiology. J Am Coll Cardiol. 1983 Jan;1(1):1–2. doi: 10.1016/s0735-1097(83)80002-3. [DOI] [PubMed] [Google Scholar]
  8. Lown B. Sudden cardiac death -- 1978. Circulation. 1979 Dec;60(7):1593–1599. doi: 10.1161/01.cir.60.7.1593. [DOI] [PubMed] [Google Scholar]
  9. Morganroth J., Michelson E. L., Horowitz L. N., Josephson M. E., Pearlman A. S., Dunkman W. B. Limitations of routine long-term electrocardiographic monitoring to assess ventricular ectopic frequency. Circulation. 1978 Sep;58(3 Pt 1):408–414. doi: 10.1161/01.cir.58.3.408. [DOI] [PubMed] [Google Scholar]
  10. Quyyumi A. A., Wright C., Mockus L., Fox K. M. Effect of partial agonist activity in beta blockers in severe angina pectoris: a double blind comparison of pindolol and atenolol. Br Med J (Clin Res Ed) 1984 Oct 13;289(6450):951–953. doi: 10.1136/bmj.289.6450.951. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Ryan M., Lown B., Horn H. Comparison of ventricular ectopic activity during 24-hour monitoring and exercise testing in patients with coronary heart disease. N Engl J Med. 1975 Jan 30;292(5):224–229. doi: 10.1056/NEJM197501302920502. [DOI] [PubMed] [Google Scholar]
  12. Schreiber T. L., Miller D. H., Silvasi D. A., Moses J. W., Borer J. S. Randomized double-blind trial of intravenous streptokinase for acute myocardial infarction. Am J Cardiol. 1986 Jul 1;58(1):47–52. doi: 10.1016/0002-9149(86)90239-0. [DOI] [PubMed] [Google Scholar]
  13. Subramanian B., Bowles M. J., Davies A. B., Raftery E. B. Combined therapy with verapamil and propranolol in chronic stable angina. Am J Cardiol. 1982 Jan;49(1):125–132. doi: 10.1016/0002-9149(82)90286-7. [DOI] [PubMed] [Google Scholar]
  14. Subramanian V. B., Bowles M. J., Khurmi N. S., Davies A. B., Raftery E. B. Randomized double-blind comparison of verapamil and nifedipine in chronic stable angina. Am J Cardiol. 1982 Oct;50(4):696–703. doi: 10.1016/0002-9149(82)91221-8. [DOI] [PubMed] [Google Scholar]
  15. Todd I. C., Ballantyne D. Antianginal efficacy of exercise training: a comparison with beta blockade. Br Heart J. 1990 Jul;64(1):14–19. doi: 10.1136/hrt.64.1.14. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from British Heart Journal are provided here courtesy of BMJ Publishing Group

RESOURCES