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. 2022 May 24;98(21):e2120–e2131. doi: 10.1212/WNL.0000000000200258

Figure 2. Percent Brain Volume Change From Baseline by Baseline pNfL in SPMS and PPMS Populations, in Patients Without Gd+ Lesions, and by Relapse Status at Baseline in the SPMS Population.

Figure 2

Percent brain volume change from baseline by baseline plasma neurofilament light (pNfL) (A) in secondary progressive multiple sclerosis (SPMS) and primary progressive multiple sclerosis (PPMS) populations, (B) in patients without gadolinium-enhancing (Gd+) lesions, and (C) by relapse status at baseline in the SPMS population. As per the INFORMS protocol, patients with relapses in the past 2 years prior to study start were excluded.