Skip to main content
PMC home page
The Western Journal of Medicine logoLink to The Western Journal of Medicine
. 1989 Mar;150(3):300–302.

A seroepidemiologic survey of human T-cell lymphotropic virus type I in two Hawaiian hematologic-oncologic practices.

J T Kimata, S A Kaneshiro, D W Kwock, S Nakamura, M M Kaneshiro, J M Nakamura
PMCID: PMC1026451  PMID: 2735036

Abstract

A seroepidemiologic survey for antibodies to the human T-cell lymphotropic virus type I (HTLV-I) was carried out in two Hawaiian hematologic-oncologic practices. Specimens of serum or plasma from 215 donors were assayed using the ELISA technique, followed by the Western blot technique to confirm antibody specificity to HTLV-I. Of 214 seropositive donors, 16 (7.5%) were positive. Of 172 donors of Japanese ancestry, 16 (9.3%) were seropositive; none were white, Chinese, Filipino, or Pacific Islander. One donor contracted the virus through blood transfusions. The results suggest that HTLV-I was introduced to Hawaii with the Japanese immigration.

Full text

PDF
300

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ben-Ishai Z., Haas M., Triglia D., Lee V., Nahmias J., Bar-Shany S., Jensen F. C. Human T-cell lymphotropic virus type-I antibodies in Falashas and other ethnic groups in Israel. Nature. 1985 Jun 20;315(6021):665–666. doi: 10.1038/315665a0. [DOI] [PubMed] [Google Scholar]
  2. Bhagavati S., Ehrlich G., Kula R. W., Kwok S., Sninsky J., Udani V., Poiesz B. J. Detection of human T-cell lymphoma/leukemia virus type I DNA and antigen in spinal fluid and blood of patients with chronic progressive myelopathy. N Engl J Med. 1988 May 5;318(18):1141–1147. doi: 10.1056/NEJM198805053181801. [DOI] [PubMed] [Google Scholar]
  3. Blattner W. A., Blayney D. W., Robert-Guroff M., Sarngadharan M. G., Kalyanaraman V. S., Sarin P. S., Jaffe E. S., Gallo R. C. Epidemiology of human T-cell leukemia/lymphoma virus. J Infect Dis. 1983 Mar;147(3):406–416. doi: 10.1093/infdis/147.3.406. [DOI] [PubMed] [Google Scholar]
  4. Blayney D. W., Blattner W. A., Robert-Guroff M., Jaffe E. S., Fisher R. I., Bunn P. A., Jr, Patton M. G., Rarick H. R., Gallo R. C. The human T-cell leukemia-lymphoma virus in the southeastern United States. JAMA. 1983 Aug 26;250(8):1048–1052. [PubMed] [Google Scholar]
  5. Botha M. C., Jones M., de Klerk W. A., Yamamoto N. Distribution and possible spread of human T-cell leukaemia virus type I in human communities in the northern and eastern Transvaal. S Afr Med J. 1985 Apr 27;67(17):668–671. [PubMed] [Google Scholar]
  6. Clark J., Saxinger C., Gibbs W. N., Lofters W., Lagranade L., Deceulaer K., Ensroth A., Robert-Guroff M., Gallo R. C., Blattner W. A. Seroepidemiologic studies of human T-cell leukemia/lymphoma virus type I in Jamaica. Int J Cancer. 1985 Jul 15;36(1):37–41. doi: 10.1002/ijc.2910360107. [DOI] [PubMed] [Google Scholar]
  7. Hino S., Yamaguchi K., Katamine S., Sugiyama H., Amagasaki T., Kinoshita K., Yoshida Y., Doi H., Tsuji Y., Miyamoto T. Mother-to-child transmission of human T-cell leukemia virus type-I. Jpn J Cancer Res. 1985 Jun;76(6):474–480. [PubMed] [Google Scholar]
  8. Hinuma Y., Komoda H., Chosa T., Kondo T., Kohakura M., Takenaka T., Kikuchi M., Ichimaru M., Yunoki K., Sato I. Antibodies to adult T-cell leukemia-virus-associated antigen (ATLA) in sera from patients with ATL and controls in Japan: a nation-wide sero-epidemiologic study. Int J Cancer. 1982 Jun 15;29(6):631–635. doi: 10.1002/ijc.2910290606. [DOI] [PubMed] [Google Scholar]
  9. Jacobson S., Raine C. S., Mingioli E. S., McFarlin D. E. Isolation of an HTLV-1-like retrovirus from patients with tropical spastic paraparesis. Nature. 1988 Feb 11;331(6156):540–543. doi: 10.1038/331540a0. [DOI] [PubMed] [Google Scholar]
  10. Kuo T. T., Chan H. L., Su I. J., Eimoto T., Maeda Y., Kikuchi M., Chen M. J., Kuan Y. Z., Chen W. J., Sun C. F. Serological survey of antibodies to the adult T-cell leukemia virus-associated antigen (HTLV-A) in Taiwan. Int J Cancer. 1985 Sep 15;36(3):345–348. [PubMed] [Google Scholar]
  11. Manzari V., Gradilone A., Barillari G., Zani M., Collalti E., Pandolfi F., De Rossi G., Liso V., Babbo P., Robert-Guroff M. HTLV-I is endemic in southern Italy: detection of the first infectious cluster in a white population. Int J Cancer. 1985 Nov 15;36(5):557–559. doi: 10.1002/ijc.2910360507. [DOI] [PubMed] [Google Scholar]
  12. Nakamura J., Kawahara K., Kwock D., Kimata J., Kaneshiro S., Nakamura S., Yanagihara E. HTLV-1 seroconversion in a 56-year-old Japanese woman undergoing chemotherapy for acute nonlymphocytic leukemia. Hawaii Med J. 1988 Jun;47(6):269-70, 273. [PubMed] [Google Scholar]
  13. Okochi K., Sato H., Hinuma Y. A retrospective study on transmission of adult T cell leukemia virus by blood transfusion: seroconversion in recipients. Vox Sang. 1984;46(5):245–253. doi: 10.1111/j.1423-0410.1984.tb00083.x. [DOI] [PubMed] [Google Scholar]
  14. Poiesz B. J., Ruscetti F. W., Gazdar A. F., Bunn P. A., Minna J. D., Gallo R. C. Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma. Proc Natl Acad Sci U S A. 1980 Dec;77(12):7415–7419. doi: 10.1073/pnas.77.12.7415. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Robert-Guroff M., Clark J., Lanier A. P., Beckman G., Melbye M., Ebbesen P., Blattner W. A., Gallo R. C. Prevalence of HTLV-I in Arctic regions. Int J Cancer. 1985 Dec 15;36(6):651–655. doi: 10.1002/ijc.2910360605. [DOI] [PubMed] [Google Scholar]
  16. Robert-Guroff M., Kalyanaraman V. S., Blattner W. A., Popovic M., Sarngadharan M. G., Maeda M., Blayney D., Catovsky D., Bunn P. A., Shibata A. Evidence for human T cell lymphoma-leukemia virus infection of family members of human T cell lymphoma-leukemia virus positive T cell leukemia-lymphoma patients. J Exp Med. 1983 Jan 1;157(1):248–258. doi: 10.1084/jem.157.1.248. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Tajima K., Tominaga S., Shimizu H., Suchi T. A hypothesis on the etiology of adult T-cell leukemia/lymphoma. Gan. 1981 Oct;72(5):684–691. [PubMed] [Google Scholar]
  18. Tajima K., Tominaga S., Suchi T., Fukui H., Komoda H., Hinuma Y. HTLV-I carriers among migrants from an ATL-endemic area to ATL non-endemic metropolitan areas in Japan. Int J Cancer. 1986 Mar 15;37(3):383–387. doi: 10.1002/ijc.2910370309. [DOI] [PubMed] [Google Scholar]
  19. Takatsuki K., Yamaguchi K., Kawano F., Hattori T., Nishimura H., Tsuda H., Sanada I., Nakada K., Itai Y. Clinical diversity in adult T-cell leukemia-lymphoma. Cancer Res. 1985 Sep;45(9 Suppl):4644s–4645s. [PubMed] [Google Scholar]
  20. Wong-Staal F., Gallo R. C. Human T-lymphotropic retroviruses. Nature. 1985 Oct 3;317(6036):395–403. doi: 10.1038/317395a0. [DOI] [PubMed] [Google Scholar]
  21. Yoshida M. Human leukemia virus associated with adult T-cell leukemia. Gan. 1983 Dec;74(6):777–789. [PubMed] [Google Scholar]

Articles from Western Journal of Medicine are provided here courtesy of BMJ Publishing Group

RESOURCES