Abstract
Some liver diseases, such as autoimmune liver disease, affect women far more often than men. Others, such as alcohol-related disease, progress more rapidly in women than in men. An increased index of suspicion will lead to improved diagnosis and earlier treatment of women with liver disease.
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- BEARN A. G., KUNKEL H. G., SLATER R. J. The problem of chronic liver disease in young women. Am J Med. 1956 Jul;21(1):3–15. doi: 10.1016/0002-9343(56)90003-1. [DOI] [PubMed] [Google Scholar]
- Berkelman R. L., Ralston M., Herndon J., Gwinn M., Bertolucci D., Dufour M. Patterns of alcohol consumption and alcohol-related morbidity and mortality. MMWR CDC Surveill Summ. 1986 Aug;35(2):1SS–5SS. [PubMed] [Google Scholar]
- COWLING D. C., MACKAY I. R., TAFT L. I. Lupoid hepatitis. Lancet. 1956 Dec 29;271(6957):1323–1326. doi: 10.1016/s0140-6736(56)91483-0. [DOI] [PubMed] [Google Scholar]
- Esquivel C. O., Van Thiel D. H., Demetris A. J., Bernardos A., Iwatsuki S., Markus B., Gordon R. D., Marsh J. W., Makowka L., Tzakis A. G. Transplantation for primary biliary cirrhosis. Gastroenterology. 1988 May;94(5 Pt 1):1207–1216. doi: 10.1016/0016-5085(88)90014-5. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hatoff D. E., Cohen M., Schweigert B. F., Talbert W. M. Nitrofurantoin: another cause of drug-induced chronic active hepatitis? A report of a patient with HLA-B8 antigen. Am J Med. 1979 Jul;67(1):117–121. doi: 10.1016/0002-9343(79)90086-x. [DOI] [PubMed] [Google Scholar]
- Homberg J. C., Abuaf N., Bernard O., Islam S., Alvarez F., Khalil S. H., Poupon R., Darnis F., Lévy V. G., Grippon P. Chronic active hepatitis associated with antiliver/kidney microsome antibody type 1: a second type of "autoimmune" hepatitis. Hepatology. 1987 Nov-Dec;7(6):1333–1339. doi: 10.1002/hep.1840070626. [DOI] [PubMed] [Google Scholar]
- Jacobson R. The contributions of sex and drinking history to the CT brain scan changes in alcoholics. Psychol Med. 1986 Aug;16(3):547–559. doi: 10.1017/s003329170001031x. [DOI] [PubMed] [Google Scholar]
- Jones B. M., Jones M. K. Alcohol effects in women during the menstrual cycle. Ann N Y Acad Sci. 1976;273:576–587. doi: 10.1111/j.1749-6632.1976.tb52931.x. [DOI] [PubMed] [Google Scholar]
- Lee S. S., Wasiljew B. K., Lee M. J. Gallstones in women younger than thirty. J Clin Gastroenterol. 1987 Feb;9(1):65–69. doi: 10.1097/00004836-198702000-00017. [DOI] [PubMed] [Google Scholar]
- Loft S., Olesen K. L., Døssing M. Increased susceptibility to liver disease in relation to alcohol consumption in women. Scand J Gastroenterol. 1987 Dec;22(10):1251–1256. doi: 10.3109/00365528708996472. [DOI] [PubMed] [Google Scholar]
- Mackay I. R., Tait B. D. HLA associations with autoimmune-type chronic active hepatitis: identification of B8-DRw3 haplotype by family studies. Gastroenterology. 1980 Jul;79(1):95–98. [PubMed] [Google Scholar]
- Maddrey W. C., Boitnott J. K. Drug-induced chronic liver disease. Gastroenterology. 1977 Jun;72(6):1348–1353. [PubMed] [Google Scholar]
- Maddrey W. C. Subdivisions of idiopathic autoimmune chronic active hepatitis. Hepatology. 1987 Nov-Dec;7(6):1372–1375. doi: 10.1002/hep.1840070631. [DOI] [PubMed] [Google Scholar]
- Manns M., Gerken G., Kyriatsoulis A., Staritz M., Meyer zum Büschenfelde K. H. Characterisation of a new subgroup of autoimmune chronic active hepatitis by autoantibodies against a soluble liver antigen. Lancet. 1987 Feb 7;1(8528):292–294. doi: 10.1016/s0140-6736(87)92024-1. [DOI] [PubMed] [Google Scholar]
- Maringhini A., Marcenò M. P., Lanzarone F., Caltagirone M., Fusco G., Di Cuonzo G., Cittadini E., Pagliaro L. Sludge and stones in gallbladder after pregnancy. Prevalence and risk factors. J Hepatol. 1987 Oct;5(2):218–223. doi: 10.1016/s0168-8278(87)80576-7. [DOI] [PubMed] [Google Scholar]
- Marshall A. W., Kingstone D., Boss M., Morgan M. Y. Ethanol elimination in males and females: relationship to menstrual cycle and body composition. Hepatology. 1983 Sep-Oct;3(5):701–706. doi: 10.1002/hep.1840030513. [DOI] [PubMed] [Google Scholar]
- Morgan M. Y., Sherlock S. Sex-related differences among 100 patients with alcoholic liver disease. Br Med J. 1977 Apr 9;1(6066):939–941. doi: 10.1136/bmj.1.6066.939. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Olomu A. B., Vickers C. R., Waring R. H., Clements D., Babbs C., Warnes T. W., Elias E. High incidence of poor sulfoxidation in patients with primary biliary cirrhosis. N Engl J Med. 1988 Apr 28;318(17):1089–1092. doi: 10.1056/NEJM198804283181703. [DOI] [PubMed] [Google Scholar]
- Parés A., Caballería J., Bruguera M., Torres M., Rodés J. Histological course of alcoholic hepatitis. Influence of abstinence, sex and extent of hepatic damage. J Hepatol. 1986;2(1):33–42. doi: 10.1016/s0168-8278(86)80006-x. [DOI] [PubMed] [Google Scholar]
- Poupon R., Chrétien Y., Poupon R. E., Ballet F., Calmus Y., Darnis F. Is ursodeoxycholic acid an effective treatment for primary biliary cirrhosis? Lancet. 1987 Apr 11;1(8537):834–836. doi: 10.1016/s0140-6736(87)91610-2. [DOI] [PubMed] [Google Scholar]
- Saunders J. B., Davis M., Williams R. Do women develop alcoholic liver disease more readily than men? Br Med J (Clin Res Ed) 1981 Apr 4;282(6270):1140–1143. doi: 10.1136/bmj.282.6270.1140. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sherlock S. The syndrome of disappearing intrahepatic bile ducts. Lancet. 1987 Aug 29;2(8557):493–496. doi: 10.1016/s0140-6736(87)91802-2. [DOI] [PubMed] [Google Scholar]
- Yeaman S. J., Fussey S. P., Danner D. J., James O. F., Mutimer D. J., Bassendine M. F. Primary biliary cirrhosis: identification of two major M2 mitochondrial autoantigens. Lancet. 1988 May 14;1(8594):1067–1070. doi: 10.1016/s0140-6736(88)91894-6. [DOI] [PubMed] [Google Scholar]

