Skip to main content
NCBI home page
The Western Journal of Medicine logoLink to The Western Journal of Medicine
. 1989 Jun;150(6):665–667.

The use of fine-needle aspiration biopsy in children.

M B Cohen, K Bottles, A R Ablin, T R Miller
PMCID: PMC1026703  PMID: 2665318

Abstract

Fine-needle aspiration biopsy has become increasingly popular for evaluating both palpable and nonpalpable masses. Judging from the current body of literature, this procedure is underused by American pediatricians. We report a series of 84 pediatric patients--younger than 16 years--who underwent 92 fine-needle aspiration biopsies to evaluate a large variety of masses. The results of 51 (55%) were benign, and 33 (36%) biopsies revealed malignancy. In two cases (2%) the findings were suggestive of malignancy, and in six cases (7%), insufficient material was rendered for diagnosis. Either histologic or clinical follow-up or both were available for 85 procedures. Based on these cases, the sensitivity of 97% and the specificity was 95%, indicating that fine-needle aspiration biopsy is a good method for screening and observing patients for various malignant tumors in a variety of organs.

Full text

PDF
665

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Abele J. S., Miller T. R., King E. B., Lowhagen T. Smearing techniques for the concentration of particles from fine needle aspiration biopsy. Diagn Cytopathol. 1985 Jan-Mar;1(1):59–65. doi: 10.1002/dc.2840010114. [DOI] [PubMed] [Google Scholar]
  2. Akhtar M., Ali M. A., Sabbah R. S., Bakry M., Sackey K., Nash E. J. Aspiration cytology of neuroblastoma. Light and electron microscopic correlations. Cancer. 1986 Feb 15;57(4):797–803. doi: 10.1002/1097-0142(19860215)57:4<797::aid-cncr2820570419>3.0.co;2-a. [DOI] [PubMed] [Google Scholar]
  3. Akhtar M., Ali M. A., Sabbah R. Aspiration cytology of Ewing's sarcoma. Light and electron microscopic correlations. Cancer. 1985 Oct 15;56(8):2051–2060. doi: 10.1002/1097-0142(19851015)56:8<2051::aid-cncr2820560828>3.0.co;2-6. [DOI] [PubMed] [Google Scholar]
  4. Akhtar M., Ali M. A., Sabbah R., Bakry M., Nash J. E. Fine-needle aspiration biopsy diagnosis of round cell malignant tumors of childhood. A combined light and electron microscopic approach. Cancer. 1985 Apr 15;55(8):1805–1817. doi: 10.1002/1097-0142(19850415)55:8<1805::aid-cncr2820550828>3.0.co;2-6. [DOI] [PubMed] [Google Scholar]
  5. BERG J. W., ROBBINS G. F. A late look at the safety of aspiration biopsy. Cancer. 1962 Jul-Aug;15:826–827. doi: 10.1002/1097-0142(196207/08)15:4<826::aid-cncr2820150419>3.0.co;2-p. [DOI] [PubMed] [Google Scholar]
  6. Bottles K., Cohen M. B., Sacks S. T. Clinician perception of fine needle aspiration cytology. Diagn Cytopathol. 1985 Jul-Sep;1(3):249–254. doi: 10.1002/dc.2840010316. [DOI] [PubMed] [Google Scholar]
  7. Bottles K., Miller T. R., Cohen M. B., Ljung B. M. Fine needle aspiration biopsy. Has its time come? Am J Med. 1986 Sep;81(3):525–531. doi: 10.1016/0002-9343(86)90309-8. [DOI] [PubMed] [Google Scholar]
  8. Bottles K., Miller T. R., Jeffrey R. B., Cohen M. B., Stoloff A., Hales M., Ljung B. M., Donegan E. Aspiration cytology characterization of inflammatory masses. West J Med. 1986 Jun;144(6):695–699. [PMC free article] [PubMed] [Google Scholar]
  9. Char D. H., Miller T. R. Fine needle biopsy in retinoblastoma. Am J Ophthalmol. 1984 Jun;97(6):686–690. doi: 10.1016/0002-9394(84)90498-7. [DOI] [PubMed] [Google Scholar]
  10. Fleisher G., Grosflam J., Selbst S., Ludwig S. Management of lymphadenitis in childhood: the role of percutaneous needle aspiration. Ann Emerg Med. 1984 Oct;13(10):908–911. doi: 10.1016/s0196-0644(84)80668-x. [DOI] [PubMed] [Google Scholar]
  11. Frable W. J. Thin-needle aspiration biopsy. A personal experience with 469 cases. Am J Clin Pathol. 1976 Feb;65(2):168–182. doi: 10.1093/ajcp/65.2.168. [DOI] [PubMed] [Google Scholar]
  12. Jereb B., Us-Krasovec M., Jereb M. Thin needle biopsy of solid tumors in children. Med Pediatr Oncol. 1978;4(3):213–220. doi: 10.1002/mpo.2950040304. [DOI] [PubMed] [Google Scholar]
  13. Livraghi T., Damascelli B., Lombardi C., Spagnoli I. Risk in fine-needle abdominal biopsy. J Clin Ultrasound. 1983 Feb-Mar;11(2):77–81. doi: 10.1002/jcu.1870110205. [DOI] [PubMed] [Google Scholar]
  14. Miller T. R., Bottles K., Abele J. S., Beckstead J. H. Neuroblastoma diagnosed by fine needle aspiration biopsy. Acta Cytol. 1985 May-Jun;29(3):461–468. [PubMed] [Google Scholar]
  15. Schaller R. T., Jr, Schaller J. F., Buschmann C., Kiviat N. The usefulness of percutaneous fine-needle aspiration biopsy in infants and children. J Pediatr Surg. 1983 Aug;18(4):398–405. doi: 10.1016/s0022-3468(83)80189-4. [DOI] [PubMed] [Google Scholar]
  16. Stewart F. W. The Diagnosis of Tumors by Aspiration. Am J Pathol. 1933;9(Suppl):801–812.3. [PMC free article] [PubMed] [Google Scholar]
  17. Taylor S. R., Nunez C. Fine-needle aspiration biopsy in a pediatric population. Report of 64 consecutive cases. Cancer. 1984 Oct 1;54(7):1449–1453. doi: 10.1002/1097-0142(19841001)54:7<1449::aid-cncr2820540738>3.0.co;2-#. [DOI] [PubMed] [Google Scholar]
  18. Woyke S., Gajewski P. Die Feinnadelpunktion in der Diagnostik von Tumoren im Kindesalter. Padiatr Grenzgeb. 1980;19(4):239–242. [PubMed] [Google Scholar]
  19. von Schreeb T., Arner O., Skovsted G., Wikstad N. Renal adenocarcinoma. Is there a risk of spreading tumour cells in diagnostic puncture? Scand J Urol Nephrol. 1967;1(3):270–276. doi: 10.3109/00365596709133549. [DOI] [PubMed] [Google Scholar]

Articles from Western Journal of Medicine are provided here courtesy of BMJ Publishing Group

RESOURCES