Skip to main content
Gut logoLink to Gut
. 1997 Feb;40(2):161–163. doi: 10.1136/gut.40.2.161

Antimicrobial peptides in the gastrointestinal tract.

Y R Mahida 1, F Rose 1, W C Chan 1
PMCID: PMC1027041  PMID: 9071924

Full text

PDF
161

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Agerberth B., Lee J. Y., Bergman T., Carlquist M., Boman H. G., Mutt V., Jörnvall H. Amino acid sequence of PR-39. Isolation from pig intestine of a new member of the family of proline-arginine-rich antibacterial peptides. Eur J Biochem. 1991 Dec 18;202(3):849–854. doi: 10.1111/j.1432-1033.1991.tb16442.x. [DOI] [PubMed] [Google Scholar]
  2. Berkowitz B. A., Bevins C. L., Zasloff M. A. Magainins: a new family of membrane-active host defense peptides. Biochem Pharmacol. 1990 Feb 15;39(4):625–629. doi: 10.1016/0006-2952(90)90138-b. [DOI] [PubMed] [Google Scholar]
  3. Boman H. G. Antibacterial peptides: key components needed in immunity. Cell. 1991 Apr 19;65(2):205–207. doi: 10.1016/0092-8674(91)90154-q. [DOI] [PubMed] [Google Scholar]
  4. Eckmann L., Kagnoff M. F., Fierer J. Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry. Infect Immun. 1993 Nov;61(11):4569–4574. doi: 10.1128/iai.61.11.4569-4574.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Eisenhauer P. B., Harwig S. S., Lehrer R. I. Cryptdins: antimicrobial defensins of the murine small intestine. Infect Immun. 1992 Sep;60(9):3556–3565. doi: 10.1128/iai.60.9.3556-3565.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Elson C. O., Sartor R. B., Tennyson G. S., Riddell R. H. Experimental models of inflammatory bowel disease. Gastroenterology. 1995 Oct;109(4):1344–1367. doi: 10.1016/0016-5085(95)90599-5. [DOI] [PubMed] [Google Scholar]
  7. Erlandsen S. L., Chase D. G. Paneth cell function: phagocytosis and intracellular digestion of intestinal microorganisms. I. Hexamita muris. J Ultrastruct Res. 1972 Nov;41(3):296–318. doi: 10.1016/s0022-5320(72)90071-8. [DOI] [PubMed] [Google Scholar]
  8. Erlandsen S. L., Parsons J. A., Taylor T. D. Ultrastructural immunocytochemical localization of lysozyme in the Paneth cells of man. J Histochem Cytochem. 1974 Jun;22(6):401–413. doi: 10.1177/22.6.401. [DOI] [PubMed] [Google Scholar]
  9. Hall J. Lymphocyte recirculation and the gut: the cellular basis of humoral immunity in the intestine. Blood Cells. 1979 Aug;5(3):479–497. [PubMed] [Google Scholar]
  10. Jones D. E., Bevins C. L. Defensin-6 mRNA in human Paneth cells: implications for antimicrobial peptides in host defense of the human bowel. FEBS Lett. 1993 Jan 4;315(2):187–192. doi: 10.1016/0014-5793(93)81160-2. [DOI] [PubMed] [Google Scholar]
  11. Jones D. E., Bevins C. L. Paneth cells of the human small intestine express an antimicrobial peptide gene. J Biol Chem. 1992 Nov 15;267(32):23216–23225. [PubMed] [Google Scholar]
  12. Keshav S., Lawson L., Chung L. P., Stein M., Perry V. H., Gordon S. Tumor necrosis factor mRNA localized to Paneth cells of normal murine intestinal epithelium by in situ hybridization. J Exp Med. 1990 Jan 1;171(1):327–332. doi: 10.1084/jem.171.1.327. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Lee J. Y., Boman A., Sun C. X., Andersson M., Jörnvall H., Mutt V., Boman H. G. Antibacterial peptides from pig intestine: isolation of a mammalian cecropin. Proc Natl Acad Sci U S A. 1989 Dec;86(23):9159–9162. doi: 10.1073/pnas.86.23.9159. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Lehrer R. I., Ganz T., Selsted M. E. Defensins: endogenous antibiotic peptides of animal cells. Cell. 1991 Jan 25;64(2):229–230. doi: 10.1016/0092-8674(91)90632-9. [DOI] [PubMed] [Google Scholar]
  15. Lehrer R. I., Lichtenstein A. K., Ganz T. Defensins: antimicrobial and cytotoxic peptides of mammalian cells. Annu Rev Immunol. 1993;11:105–128. doi: 10.1146/annurev.iy.11.040193.000541. [DOI] [PubMed] [Google Scholar]
  16. Lundberg J. M., Hemsén A., Andersson M., Hökfelt T., Mutt V., Boman H. G. Cecropin P1-like immunoreactivity in epithelial cells of duodenum and glucagon cells of the pancreas. Acta Physiol Scand. 1991 Mar;141(3):443–444. doi: 10.1111/j.1748-1716.1991.tb09104.x. [DOI] [PubMed] [Google Scholar]
  17. Mahida Y. R., Makh S., Hyde S., Gray T., Borriello S. P. Effect of Clostridium difficile toxin A on human intestinal epithelial cells: induction of interleukin 8 production and apoptosis after cell detachment. Gut. 1996 Mar;38(3):337–347. doi: 10.1136/gut.38.3.337. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. McCormick B. A., Colgan S. P., Delp-Archer C., Miller S. I., Madara J. L. Salmonella typhimurium attachment to human intestinal epithelial monolayers: transcellular signalling to subepithelial neutrophils. J Cell Biol. 1993 Nov;123(4):895–907. doi: 10.1083/jcb.123.4.895. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Moore K. S., Bevins C. L., Brasseur M. M., Tomassini N., Turner K., Eck H., Zasloff M. Antimicrobial peptides in the stomach of Xenopus laevis. J Biol Chem. 1991 Oct 15;266(29):19851–19857. [PubMed] [Google Scholar]
  20. Ouellette A. J., Greco R. M., James M., Frederick D., Naftilan J., Fallon J. T. Developmental regulation of cryptdin, a corticostatin/defensin precursor mRNA in mouse small intestinal crypt epithelium. J Cell Biol. 1989 May;108(5):1687–1695. doi: 10.1083/jcb.108.5.1687. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Ouellette A. J., Hsieh M. M., Nosek M. T., Cano-Gauci D. F., Huttner K. M., Buick R. N., Selsted M. E. Mouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms. Infect Immun. 1994 Nov;62(11):5040–5047. doi: 10.1128/iai.62.11.5040-5047.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Ouellette A. J., Miller S. I., Henschen A. H., Selsted M. E. Purification and primary structure of murine cryptdin-1, a Paneth cell defensin. FEBS Lett. 1992 Jun 15;304(2-3):146–148. doi: 10.1016/0014-5793(92)80606-h. [DOI] [PubMed] [Google Scholar]
  23. PATERSON J. C., WATSON S. H. Paneth cell metaplasia in ulcerative colitis. Am J Pathol. 1961 Feb;38:243–249. [PMC free article] [PubMed] [Google Scholar]
  24. Reilly D. S., Tomassini N., Bevins C. L., Zasloff M. A Paneth cell analogue in Xenopus small intestine expresses antimicrobial peptide genes: conservation of an intestinal host-defense system. J Histochem Cytochem. 1994 Jun;42(6):697–704. doi: 10.1177/42.6.8189032. [DOI] [PubMed] [Google Scholar]
  25. Schonwetter B. S., Stolzenberg E. D., Zasloff M. A. Epithelial antibiotics induced at sites of inflammation. Science. 1995 Mar 17;267(5204):1645–1648. doi: 10.1126/science.7886453. [DOI] [PubMed] [Google Scholar]
  26. Selsted M. E., Miller S. I., Henschen A. H., Ouellette A. J. Enteric defensins: antibiotic peptide components of intestinal host defense. J Cell Biol. 1992 Aug;118(4):929–936. doi: 10.1083/jcb.118.4.929. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. Storici P., Zanetti M. A cDNA derived from pig bone marrow cells predicts a sequence identical to the intestinal antibacterial peptide PR-39. Biochem Biophys Res Commun. 1993 Nov 15;196(3):1058–1065. doi: 10.1006/bbrc.1993.2358. [DOI] [PubMed] [Google Scholar]
  28. Wolff A., Moreira J. E., Bevins C. L., Hand A. R., Fox P. C. Magainin-like immunoreactivity in human submandibular and labial salivary glands. J Histochem Cytochem. 1990 Nov;38(11):1531–1534. doi: 10.1177/38.11.2212614. [DOI] [PubMed] [Google Scholar]
  29. Zasloff M. Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor. Proc Natl Acad Sci U S A. 1987 Aug;84(15):5449–5453. doi: 10.1073/pnas.84.15.5449. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. de Sauvage F. J., Keshav S., Kuang W. J., Gillett N., Henzel W., Goeddel D. V. Precursor structure, expression, and tissue distribution of human guanylin. Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):9089–9093. doi: 10.1073/pnas.89.19.9089. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Gut are provided here courtesy of BMJ Publishing Group

RESOURCES