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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1983 Jan;46(1):75–77. doi: 10.1136/jnnp.46.1.75

Gilles de la Tourette's syndrome in monozygotic twins

Jack Waserman *, Samarthji Lal *, Serge Gauthier
PMCID: PMC1027267  PMID: 6573436

Abstract

Concordance is reported of Gilles de la Tourette syndrome in a male twin pair in whom phenotyping revealed a >98·7% probability that they were monozygotic. The development and extent of the illness differed markedly in the two subjects. Our findings are compatible with the view that there is a genetic form of Gilles de la Tourette syndrome.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bremness A. B., Sverd J. Methylphenidate-induced Tourette syndrome: case report. Am J Psychiatry. 1979 Oct;136(10):1334–1335. doi: 10.1176/ajp.136.10.1334. [DOI] [PubMed] [Google Scholar]
  2. ELLISON R. M. GILLES DE LA TOURETTE'S SYNDROME. Med J Aust. 1964 Feb 1;1:153–155. [PubMed] [Google Scholar]
  3. Escalar G., Majeron M. A., Finavera L., Zamberletti P. Contributo alla coinoscenza della sindrome di Gilles de la Tourette. Studio su due gemelli. Minerva Med. 1972 Sep 15;63(64):3517–3522. [PubMed] [Google Scholar]
  4. Fras I., Karlavage J. The use of methylphenidate and imipramine in Gilles de la Tourette's disease in children. Am J Psychiatry. 1977 Feb;134(2):195–197. doi: 10.1176/ajp.134.2.195. [DOI] [PubMed] [Google Scholar]
  5. Friedhoff A. J. Receptor sensitivity modification (RSM)--a new paradigm for the potential treatment of some hormonal and transmitter disturbances. Compr Psychiatry. 1977 Jul-Aug;18(4):309–317. doi: 10.1016/0010-440x(77)90001-3. [DOI] [PubMed] [Google Scholar]
  6. Golden G. S. The effect of central nervous system stimulants on Tourette syndrome. Ann Neurol. 1977 Jul;2(1):69–70. doi: 10.1002/ana.410020113. [DOI] [PubMed] [Google Scholar]
  7. Pollack M. A., Cohen N. L., Friedhoff A. J. Gilles de la Tourette's syndrome. Familial occurrence and precipitation by methylphenidate therapy. Arch Neurol. 1977 Oct;34(10):630–632. doi: 10.1001/archneur.1977.00500220064011. [DOI] [PubMed] [Google Scholar]
  8. Sleator E. K. Deleterious effects of drugs used for hyperactivity on patients with Gilles de la Tourette syndrome. Clin Pediatr (Phila) 1980 Jul;19(7):453–454. doi: 10.1177/000992288001900704. [DOI] [PubMed] [Google Scholar]
  9. Wassman E. R., Eldridge R., Abuzzahab S., Sr, Nee L. Gilles de la Tourette syndrome: clinical and genetic studies in a midwestern city. Neurology. 1978 Mar;28(3):304–307. doi: 10.1212/wnl.28.3.304. [DOI] [PubMed] [Google Scholar]
  10. Wilson R. S., Garron D. C., Klawans H. L. Significance of genetic factors in Gilles de la Tourette syndrome: a review. Behav Genet. 1978 Nov;8(6):503–510. doi: 10.1007/BF01067479. [DOI] [PubMed] [Google Scholar]

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