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. 2023 Feb 9;141(22):2698–2712. doi: 10.1182/blood.2022018924

Table 2.

Seven criteria for identifying cell type–specific functional extragenic genomic safe harbors (eGSHs)

1. Distance of >50 kb from 5′ end of any gene
2. Distance of >300 kb from any cancer-related genes
3. Distance of >300 kb from any miRNA
4. Outside a gene transcription unit
5. Outside of ultraconserved regions
6. Outside of noncoding RNAs
7. Within ATAC-seq peak in activated state and proximity to ATAC-seq peaks (<50 kb) and active genes in resting state (<200 kb)