Abstract
Tetrahydrobiopterin metabolism was shown to be disturbed in 18 patients with senile dementia of Alzheimer type. This may have a bearing on the pathogenesis of the disease.
Full text
PDF



Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Adolfsson R., Gottfries C. G., Roos B. E., Winblad B. Changes in the brain catecholamines in patients with dementia of Alzheimer type. Br J Psychiatry. 1979 Sep;135:216–223. doi: 10.1192/bjp.135.3.216. [DOI] [PubMed] [Google Scholar]
- Berger B., Escourolle R., Moyne M. A. Axones catécholaminergiques du cortex cérébral humain. Observation, en histofluorescence, de biopsies cérébrales dont 2 cas de maladie d'Alzheimer. Rev Neurol (Paris) 1976 Mar;132(3):183–194. [PubMed] [Google Scholar]
- Bowen D. M., White P., Spillane J. A., Goodhardt M. J., Curzon G., Iwangoff P., Meier-Ruge W., Davison A. N. Accelerated ageing or selective neuronal loss as an important cause of dementia? Lancet. 1979 Jan 6;1(8106):11–14. doi: 10.1016/s0140-6736(79)90454-9. [DOI] [PubMed] [Google Scholar]
- Davies P., Maloney A. J. Selective loss of central cholinergic neurons in Alzheimer's disease. Lancet. 1976 Dec 25;2(8000):1403–1403. doi: 10.1016/s0140-6736(76)91936-x. [DOI] [PubMed] [Google Scholar]
- Davies P. Neurotransmitter-related enzymes in senile dementia of the Alzheimer type. Brain Res. 1979 Aug 3;171(2):319–327. doi: 10.1016/0006-8993(79)90336-6. [DOI] [PubMed] [Google Scholar]
- Leeming R. J., Blair J. A., Melikian V., O'Gorman D. J. Biopterin derivatives in human body fluids and tissues. J Clin Pathol. 1976 May;29(5):444–451. doi: 10.1136/jcp.29.5.444. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Leeming R. J., Blair J. A., Rey F. Letter: Biopterin derivatives in atypical phenylketonuria. Lancet. 1976 Jan 10;1(7950):99–100. doi: 10.1016/s0140-6736(76)90204-x. [DOI] [PubMed] [Google Scholar]
- Leeming R. J., Blair J. A. The effects of pathological and normal physiological processes on biopterin derivative levels in man. Clin Chim Acta. 1980 Nov 20;108(1):103–111. doi: 10.1016/0009-8981(80)90298-3. [DOI] [PubMed] [Google Scholar]
- Mann J. J., Stanley M., Neophytides A., de Leon M. J., Ferris S. H., Gershon S. Central amine metabolism in Alzheimer's disease: in vivo relationship to cognitive deficit. Neurobiol Aging. 1981 Spring;2(1):57–60. doi: 10.1016/0197-4580(81)90060-9. [DOI] [PubMed] [Google Scholar]
- Perry E. K., Perry R. H., Blessed G., Tomlinson B. E. Necropsy evidence of central cholinergic deficits in senile dementia. Lancet. 1977 Jan 22;1(8004):189–189. doi: 10.1016/s0140-6736(77)91780-9. [DOI] [PubMed] [Google Scholar]
- Rey F., Leeming R. J., Blair J. A., Rey J. Biopterin defect in a normal-appearing child affected by a transient phenylketonuria. Arch Dis Child. 1980 Aug;55(8):637–639. doi: 10.1136/adc.55.8.637. [DOI] [PMC free article] [PubMed] [Google Scholar]
- White P., Hiley C. R., Goodhardt M. J., Carrasco L. H., Keet J. P., Williams I. E., Bowen D. M. Neocortical cholinergic neurons in elderly people. Lancet. 1977 Mar 26;1(8013):668–671. doi: 10.1016/s0140-6736(77)92114-6. [DOI] [PubMed] [Google Scholar]
- Williams A. C., Levine R. A., Chase T. N., Lovenberg W., Calne D. B. CFS hydroxylase cofactor levels in some neurological diseases. J Neurol Neurosurg Psychiatry. 1980 Aug;43(8):735–738. doi: 10.1136/jnnp.43.8.735. [DOI] [PMC free article] [PubMed] [Google Scholar]
