Abstract
An unusual combination of disconnective syndromes is reported: transcortical motor aphasia, left arm apraxia and optic ataxia. Neuropathological examination showed a left parieto-occipital and a subcortical frontal infarct and a lesion of the dorsal part of the posterior two-fifths of the callosum. The frontal lesion caused the transcortical motor aphasia and produced the left arm apraxia. Visuomotor incoordination in the right hemispace was due to the left parieto-occipital infarct, while the crossed optic ataxia in the left hemispace was attributed to the callosal lesion. It is proposed that the pathway that serves crossed visual reaching passes through the dorsal part of the posterior callosum. This case reinforces the growing evidence that fibres in the corpus callosum are arranged in ventro-dorsal functional lamination.
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- Ajax E. T., Schenkenberg T., Kosteljanetz M. Alexia without agraphia and the inferior splenium. Neurology. 1977 Jul;27(7):685–688. doi: 10.1212/wnl.27.7.685. [DOI] [PubMed] [Google Scholar]
- Benson D. F., Segarra J., Albert M. L. Visual agnosia-prosopagnosia. A clinicopathologic correlation. Arch Neurol. 1974 Apr;30(4):307–310. doi: 10.1001/archneur.1974.00490340035007. [DOI] [PubMed] [Google Scholar]
- Boller F., Cole M., Kim Y., Mack J. L., Patawaran C. Optic ataxia: clinical-radiological correlations with the EMIscan. J Neurol Neurosurg Psychiatry. 1975 Oct;38(10):954–958. doi: 10.1136/jnnp.38.10.954. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Brinkman J., Kuypers H. G. Cerebral control of contralateral and ipsilateral arm, hand and finger movements in the split-brain rhesus monkey. Brain. 1973 Dec;96(4):653–674. doi: 10.1093/brain/96.4.653. [DOI] [PubMed] [Google Scholar]
- Castaigne P., Pertuiset B., Rondot P., de Recondo J. Ataxie optique dans les deux hémichamps visuels homonymes gauches après exérèse chirurgicale d'un anévrysme artériel de la paroi du ventricule latéral. Rev Neurol (Paris) 1971 Apr;124(4):261–268. [PubMed] [Google Scholar]
- Castaigne P., Rondot P., Dumas J. L., Tempier P. Ataxie optique localisée au coté gauche dans les deux hémichamps visuels homonymes gauches. Rev Neurol (Paris) 1975 Jan;131(1):23–28. [PubMed] [Google Scholar]
- Cumming W. J., Hurwitz L. J., Perl N. T. A study of patient who had alexia without agraphia. J Neurol Neurosurg Psychiatry. 1970 Feb;33(1):34–39. doi: 10.1136/jnnp.33.1.34. [DOI] [PMC free article] [PubMed] [Google Scholar]
- DOWNER J. L. Changes in visually guided behaviour following midsagittal division of optic chiasm and corpus callosum in monkey (Macaca mulatta). Brain. 1959 Jun;82:251–259. doi: 10.1093/brain/82.2.251. [DOI] [PubMed] [Google Scholar]
- Damasio A. R., Chui H. C., Corbett J., Kassel N. Posterior callosal section in a non-epileptic patient. J Neurol Neurosurg Psychiatry. 1980 Apr;43(4):351–356. doi: 10.1136/jnnp.43.4.351. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dimond S. J., Scammell R. E., Brouwers E. Y., Weeks R. Functions of the centre section (trunk) of the corpus callosum in man. Brain. 1977 Sep;100(3):543–562. doi: 10.1093/brain/100.3.543. [DOI] [PubMed] [Google Scholar]
- Gazzaniga M. S., Bogen J. E., Sperry R. W. Observations on visual perception after disconnexion of the cerebral hemispheres in man. Brain. 1965 Jun;88(2):221–236. doi: 10.1093/brain/88.2.221. [DOI] [PubMed] [Google Scholar]
- Gazzaniga M. S., Freedman H. Observations on visual processes after posterior callosal section. Neurology. 1973 Oct;23(10):1126–1130. doi: 10.1212/wnl.23.10.1126. [DOI] [PubMed] [Google Scholar]
- Gazzaniga M. S. Visuomotor integration in split-brain monkeys with other cerebral lesions. Exp Neurol. 1966 Nov;16(3):289–298. doi: 10.1016/0014-4886(66)90065-3. [DOI] [PubMed] [Google Scholar]
- Geschwind N., Fusillo M. Color-naming defects in association with alexia. Arch Neurol. 1966 Aug;15(2):137–146. doi: 10.1001/archneur.1966.00470140027004. [DOI] [PubMed] [Google Scholar]
- Greenblatt S. H. Alexia without agraphia or hemianopsia. Anatomical analysis of an autopsied case. Brain. 1973 Jun;96(2):307–316. doi: 10.1093/brain/96.2.307. [DOI] [PubMed] [Google Scholar]
- HECAEN H., DE AJURIAGUERRA J. Balint's syndrome (psychic paralysis of visual fixation) and its minor forms. Brain. 1954;77(3):373–400. doi: 10.1093/brain/77.3.373. [DOI] [PubMed] [Google Scholar]
- HECAEN H., de AJURIAGUERRA J., ROUQUES L., DAVID M., DELL M. B. Paralysie psychique du regard de Balint au cours de l'evolution d'une leucoencéphalite type Balo. Rev Neurol (Paris) 1950 Aug;83(2):81–104. [PubMed] [Google Scholar]
- Haaxma R., Kuypers H. G. Intrahemispheric cortical connexions and visual guidance of hand and finger movements in the rhusus monkey. Brain. 1975 Jun;98(2):239–260. doi: 10.1093/brain/98.2.239. [DOI] [PubMed] [Google Scholar]
- Heilman K. M., Valenstein E. Mechanisms underlying hemispatial neglect. Ann Neurol. 1979 Feb;5(2):166–170. doi: 10.1002/ana.410050210. [DOI] [PubMed] [Google Scholar]
- Hyvärinen J., Poranen A. Function of the parietal associative area 7 as revealed from cellular discharges in alert monkeys. Brain. 1974 Dec;97(4):673–692. doi: 10.1093/brain/97.1.673. [DOI] [PubMed] [Google Scholar]
- Iwata M., Sugishita M., Toyokura Y., Yamada R., Yoshioka M. Etude sur le syndrome de disconnexion visuo-linguale après la transection du splénium du corps calleux. Troubles de la verbalisation des informations visuelles dans l'hémisphère mineur. J Neurol Sci. 1974 Nov;23(3):421–432. doi: 10.1016/0022-510x(74)90159-2. [DOI] [PubMed] [Google Scholar]
- Lund J. S., Downer J. L., Lumley J. S. Visual control of limb movement following section of optic chiasm and corpus callosum in the monkey. Cortex. 1970 Sep;6(3):323–346. doi: 10.1016/s0010-9452(70)80021-1. [DOI] [PubMed] [Google Scholar]
- Michel F., Schott B., Boucher M., Kopp N. Alexie sans agraphie chez un malade ayant un hémisphère gauche déafférenté (hémianopsie, hémianesthésie, hémianacousie). Rev Neurol (Paris) 1979 Apr-May;135(4):347–364. [PubMed] [Google Scholar]
- Moll L., Kuypers H. G. Premotor cortical ablations in monkeys: contralateral changes in visually guided reaching behavior. Science. 1977 Oct 21;198(4314):317–319. doi: 10.1126/science.410103. [DOI] [PubMed] [Google Scholar]
- Mountcastle V. B., Lynch J. C., Georgopoulos A., Sakata H., Acuna C. Posterior parietal association cortex of the monkey: command functions for operations within extrapersonal space. J Neurophysiol. 1975 Jul;38(4):871–908. doi: 10.1152/jn.1975.38.4.871. [DOI] [PubMed] [Google Scholar]
- Pandya D. N., Karol E. A., Heilbronn D. The topographical distribution of interhemispheric projections in the corpus callosum of the rhesus monkey. Brain Res. 1971 Sep 10;32(1):31–43. doi: 10.1016/0006-8993(71)90153-3. [DOI] [PubMed] [Google Scholar]
- Pandya D. N., Vignolo L. A. Intra- and interhemispheric projections of the precentral, premotor and arcuate areas in the rhesus monkey. Brain Res. 1971 Mar 5;26(2):217–233. [PubMed] [Google Scholar]
- Perenin M. T., Jeannerod M. Residual vision in cortically blind hemiphields. Neuropsychologia. 1975 Jan;13(1):1–7. doi: 10.1016/0028-3932(75)90041-x. [DOI] [PubMed] [Google Scholar]
- Ratcliff G., Davies-Jones G. A. Defective visual localization in focal brain wounds. Brain. 1972;95(1):49–60. doi: 10.1093/brain/95.1.49. [DOI] [PubMed] [Google Scholar]
- Robinson D. L., Goldberg M. E., Stanton G. B. Parietal association cortex in the primate: sensory mechanisms and behavioral modulations. J Neurophysiol. 1978 Jul;41(4):910–932. doi: 10.1152/jn.1978.41.4.910. [DOI] [PubMed] [Google Scholar]
- Rondot P., De Recondo J. Ataxie optique: trouble de la coordination visuo-motrice. Brain Res. 1974 May 17;71(2-3):367–375. doi: 10.1016/0006-8993(74)90980-9. [DOI] [PubMed] [Google Scholar]
- Rondot P., de Recondo J., Dumas J. L. Visuomotor ataxia. Brain. 1977 Jun;100(2):355–376. doi: 10.1093/brain/100.2.355. [DOI] [PubMed] [Google Scholar]
- Van Der Staak C. Intra- and interhemispheric visual-motor control of human arm movements. Neuropsychologia. 1975 Oct;13(4):439–448. doi: 10.1016/0028-3932(75)90067-6. [DOI] [PubMed] [Google Scholar]
- Volpe B. T., Sidtis J. J., Holtzman J. D., Wilson D. H., Gazzaniga M. S. Cortical mechanisms involved in praxis: observations following partial and complete section of the corpus callosum in man. Neurology. 1982 Jun;32(6):645–650. doi: 10.1212/wnl.32.6.645. [DOI] [PubMed] [Google Scholar]



