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Schematic models of different types of IGR IRES. Models of (A) a type 6a IRES (e.g., cricket paralysis virus), (B) a type 6b IRES (e.g., Taura syndrome virus), (C) a type 6c IRES (e.g., Halastavi árva virus), and (D) a type 6d IRES (e.g., nedicistrovirus), labeled to indicate domain 1 (PKII) colored blue, domain 2 (PKIII) colored red and domain 3 (PKI) colored green, stem–loops SLIII, SLIV, and SLV, and the L1.1a loop.
