Abstract
In two prospective studies of anticonvulsant therapy there was a high incidence of drug-induced skin reactions to phenytoin (7%) and carbamazepine (16.6%). High initial serum concentrations of these drugs appeared to be a factor influencing the occurrence of such skin reactions.
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Selected References
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- Foy P. M., Copeland G. P., Shaw M. D. The incidence of postoperative seizures. Acta Neurochir (Wien) 1981;55(3-4):253–264. doi: 10.1007/BF01808441. [DOI] [PubMed] [Google Scholar]
- Gayford J. J., Redpath T. H. The side-effects of carbamazepine. Proc R Soc Med. 1969 Jun;62(6):615–616. doi: 10.1177/003591576906200638. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Schmidt D., Vogel A. Plasmakonzentrationen nach injektion and infusion von phenytoin. Klin Wochenschr. 1977 Mar 1;55(5):219–223. doi: 10.1007/BF01487714. [DOI] [PubMed] [Google Scholar]
- Turnbull D. M., Rawlins M. D., Weightman D., Chadwick D. W. A comparison of phenytoin and valproate in previously untreated adult epileptic patients. J Neurol Neurosurg Psychiatry. 1982 Jan;45(1):55–59. doi: 10.1136/jnnp.45.1.55. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wilson J. T., Höjer B., Rane A. Loading and conventional dose therapy with phenytoin in children: kinetic profile of parent drug and main metabolite in plasma. Clin Pharmacol Ther. 1976 Jul;20(1):48–58. doi: 10.1002/cpt197620148. [DOI] [PubMed] [Google Scholar]
