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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1984 Oct;47(10):1131–1133. doi: 10.1136/jnnp.47.10.1131

Anticonvulsant drugs alter plasma tryptophan concentrations in epileptic patients: implications for antiepileptic action and mental function.

J A Pratt, P Jenner, A L Johnson, S D Shorvon, E H Reynolds
PMCID: PMC1028047  PMID: 6438278

Abstract

In epileptic patients carbamazepine and diphenylhydantoin have opposite effects on whole and free plasma tryptophan concentrations, the former elevating and the latter depressing them. It is unlikely that these observations relate to the similar anti-epileptic properties of these two drugs but they may relate to their different effects on mental function and mood.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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