Abstract
Plasma fibrin/fibrinogen degradation product (FDP) determinations and CT scans were performed in 26 patients on the first, third, and seventh day after head injury. Plasma FDP concentrations were increased in the patients with cerebral contusion shown on CT scans, while the plasma FDP values were normal in the patients with various sized epidural haematomas. Furthermore, the plasma FDP elevation appeared to be more marked and more prolonged in the patients with severe contusion than in those with mild contusion. These findings suggest that the degree of the increase in plasma FDP is proportional to the amount of brain tissue destruction.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Drayer B. P., Poser C. M. Disseminated intravascular coagulation and head trauma. Two case studies. JAMA. 1975 Jan 13;231(2):174–175. [PubMed] [Google Scholar]
- Goodnight S. H., Kenoyer G., Rapaport S. I., Patch M. J., Lee J. A., Kurze T. Defibrination after brain-tissue destruction: A serious complication of head injury. N Engl J Med. 1974 May 9;290(19):1043–1047. doi: 10.1056/NEJM197405092901903. [DOI] [PubMed] [Google Scholar]
- Jennett B., Teasdale G., Braakman R., Minderhoud J., Heiden J., Kurze T. Prognosis of patients with severe head injury. Neurosurgery. 1979 Apr;4(4):283–289. doi: 10.1227/00006123-197904000-00001. [DOI] [PubMed] [Google Scholar]
- Keimowitz R. M., Annis B. L. Disseminated intravascular coagulation associated with massive brain injury. J Neurosurg. 1973 Aug;39(2):178–180. doi: 10.3171/jns.1973.39.2.0178. [DOI] [PubMed] [Google Scholar]
- Levati A., Farina M. L., Vecchi G., Rossanda M., Marrubini M. B. Prognosis of severe head injuries. J Neurosurg. 1982 Dec;57(6):779–783. doi: 10.3171/jns.1982.57.6.0779. [DOI] [PubMed] [Google Scholar]
- McGauley J. L., Miller C. A., Penner J. A. Diagnosis and treatment of diffuse intravascular coagulation following cerebral trauma. Case report. J Neurosurg. 1975 Sep;43(3):374–376. doi: 10.3171/jns.1975.43.3.0374. [DOI] [PubMed] [Google Scholar]
- Pondaag W. Disseminated intravascular coagulation related to outcome in head injury. Acta Neurochir Suppl (Wien) 1979;28(1):98–102. doi: 10.1007/978-3-7091-4088-8_22. [DOI] [PubMed] [Google Scholar]
- Yamaura A., Nakamura T., Ono J., Ariga N., Horie T., Shinohara Y., Isobe K., Kokubo Y., Makino H. Prognostic value of CT in head injuries. Neurol Med Chir (Tokyo) 1981 Jul;21(7):685–696. doi: 10.2176/nmc.21.685. [DOI] [PubMed] [Google Scholar]
- van der Sande J. J., Veltkamp J. J., Boekhout-Mussert R. J., Bouwhuis-Hoogerwerf M. L. Head injury and coagulation disorders. J Neurosurg. 1978 Sep;49(3):357–365. doi: 10.3171/jns.1978.49.3.0357. [DOI] [PubMed] [Google Scholar]