Abstract
The relationship between the levels of serum acute phase reactant proteins (alpha 1-acid glycoprotein, alpha 1-antitrypsin, haptoglobin) was investigated in patients with glioblastoma multiforme in relation to their prognosis. Alpha 1-acid glycoprotein was higher in the patients who died within one year after admission than in those with a longer survival time. It is suggested that serum alpha 1-acid glycoprotein profiles provide prognostic information in patients with glioblastoma multiforme.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Apffel C. A., Peters J. H. Tumors and serum glycoproteins. The 'symbodies'. Prog Exp Tumor Res. 1969;12:1–54. [PubMed] [Google Scholar]
- Baskies A. M., Chretien P. B., Weiss J. F., Makuch R. W., Beveridge R. A., Catalona W. J., Spiegel H. E. Serum glycoproteins in cancer patients: first report of correlations with in vitro and in vivo parameters of cellular immunity. Cancer. 1980 Jun 15;45(12):3050–3060. doi: 10.1002/1097-0142(19800615)45:12<3050::aid-cncr2820451229>3.0.co;2-8. [DOI] [PubMed] [Google Scholar]
- Brooks W. H., Caldwell H. D., Mortara R. H. Immune responses in patients with gliomas. Surg Neurol. 1974 Nov;2(6):419–423. [PubMed] [Google Scholar]
- Chiu K. M., Mortensen R. F., Osmand A. P., Gewurz H. Interactions of alpha1-acid glycoprotein with the immune system. I. Purification and effects upon lymphocyte responsiveness. Immunology. 1977 Jun;32(6):997–1005. [PMC free article] [PubMed] [Google Scholar]
- Cooper E. H., Turner R., Geekie A., Neville A. M., Goligher J. C., Graham N. G., Giles G. R., Hall R., Macadam W. A. Alpha-globulins in the surveillance of colorectal cancer. Biomedicine. 1976 Jun;24(3):171–178. [PubMed] [Google Scholar]
- Gahmberg C. G., Andersson L. C. Leukocyte surface origin of human alpha1-acid glycoprotein (orosomucoid). J Exp Med. 1978 Aug 1;148(2):507–521. doi: 10.1084/jem.148.2.507. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Harris C. C., Primack A., Cohen M. H. Elevated alpha1-Antitrypsin serum levels in lung cancer patients. Cancer. 1974 Aug;34(2):280–281. doi: 10.1002/1097-0142(197408)34:2<280::aid-cncr2820340210>3.0.co;2-4. [DOI] [PubMed] [Google Scholar]
- Larsen B., Heron I., Thorling E. B. Elevated serum Cu in Hodgkin's disease and inhibitory effects of ceruloplasmin on lymphocyte response in vitro. Eur J Cancer. 1980 Mar;16(3):415–421. doi: 10.1016/0014-2964(80)90361-8. [DOI] [PubMed] [Google Scholar]
- Latner A. L., Turner G. A., Lamin M. M. Plasma alpha-1-antitrypsin levels in early and late carcinoma of the cervix. Oncology. 1976;33(1):12–14. doi: 10.1159/000225093. [DOI] [PubMed] [Google Scholar]
- Lipsky J. J., Berninger R. W., Hyman L. R., Talamo R. C. Presence of alpha-1-antitrypsin on mitogen-stimulated human lymphocytes. J Immunol. 1979 Jan;122(1):24–26. [PubMed] [Google Scholar]
- Mortensen R. F., Gewurz H. Effects of C-reactive protein on the lymphoid system. II. Inhibition of mixed lymphocyte reactivity and generation of cytotoxic lymphocytes. J Immunol. 1976 May;116(5):1244–1250. [PubMed] [Google Scholar]
- Mueller W. K., Handschumacher R., Wade M. E. Serum haptoglobin in patients with ovarian malignancies. Obstet Gynecol. 1971 Sep;38(3):427–435. [PubMed] [Google Scholar]
- Roberts J. G., Keyser J. W., Baum M. Serum alpha-1-acid glycoprotein as an index of dissemination in breast cancer. Br J Surg. 1975 Oct;62(10):816–819. doi: 10.1002/bjs.1800621017. [DOI] [PubMed] [Google Scholar]
- Samak R., Edelstein R., Israel L. Immunosuppressive effect of acute-phase reactant proteins in vitro and its relevance to cancer. Cancer Immunol Immunother. 1982;13(1):38–43. doi: 10.1007/BF00200198. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ward A. M., Cooper E. H., Houghton A. L. Acute phase reactant proteins in prostatic cancer. Br J Urol. 1977 Oct;49(5):411–418. doi: 10.1111/j.1464-410x.1977.tb04168.x. [DOI] [PubMed] [Google Scholar]
- Weiss J. F., Morantz R. A., Bradley W. P., Chretien P. B. Serum acute-phase proteins and immunoglobulins in patients with gliomas. Cancer Res. 1979 Feb;39(2 Pt 1):542–544. [PubMed] [Google Scholar]
- Yoshimura S., Tamaoki N., Ueyama Y., Hata J. Plasma protein production by human tumors xenotransplanted in nude mice. Cancer Res. 1978 Oct;38(10):3474–3478. [PubMed] [Google Scholar]
- te Velde E. R., Berrens L., Zegers B. J., Ballieux R. E. Acute phase reactants and complement components as indicators of recurrence in human cervical cancer. Eur J Cancer. 1979 Jun;15(6):893–899. doi: 10.1016/0014-2964(79)90231-7. [DOI] [PubMed] [Google Scholar]